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ONTOLOGY REPORT - ANNOTATIONS


Term:selective autophagy
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Accession:GO:0061912 term browser browse the term
Definition:The macroautophagy process in which specific structures are targeted by the autophagy process.


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selective autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SQSTM1 sequestosome 1 involved_in ISO (PMID:22622177) UniProt PMID:22622177 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACBD5 acyl-CoA binding domain containing 5 NOT|involved_in ISO (PMID:24535825) UniProt PMID:24535825 NCBI chr 2:6,873,207...6,923,152
Ensembl chr 2:6,874,831...6,922,082
JBrowse link
G ATG5 autophagy related 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485
JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:33,364,569...33,369,080
Ensembl chr 7:33,365,045...33,368,969
JBrowse link
G SQSTM1 sequestosome 1 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051
JBrowse link
G WDFY3 WD repeat and FYVE domain containing 3 involved_in ISO (PMID:20168092), (PMID:20417604) UniProt PMID:20168092 PMID:20417604 NCBI chr32:8,430,856...8,662,988
Ensembl chr32:8,433,080...8,695,859
JBrowse link
G WDR81 WD repeat domain 81 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chr 9:45,860,200...45,875,439
Ensembl chr 9:45,859,455...45,875,439
JBrowse link
glycophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1CC1 RB1 inducible coiled-coil 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:4,445,668...4,544,223
Ensembl chr29:4,375,785...4,517,168
JBrowse link
G STBD1 starch binding domain 1 involved_in ISO (PMID:20810658) GO_Central PMID:20810658 NCBI chr32:932,245...953,070
Ensembl chr32:951,698...952,897
JBrowse link
lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor involved_in ISO (PMID:29902443) UniProt PMID:29902443 NCBI chr17:48,613,648...48,617,091
Ensembl chr17:48,613,725...48,616,728
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISS GO_Central GO_REF:0000024 NCBI chr20:2,704,716...2,776,518
Ensembl chr20:2,704,752...2,826,636
JBrowse link
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:21753002)
(PMID:25215947)
ParkinsonsUK-UCL PMID:21753002 PMID:25215947 NCBI chr18:42,903,815...43,073,918
Ensembl chr18:42,932,513...43,072,827
JBrowse link
G ATG13 autophagy related 13 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chr18:42,834,538...42,886,873
Ensembl chr18:42,836,755...42,886,855
JBrowse link
G ATG14 autophagy related 14 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chr 8:31,199,097...31,234,200
Ensembl chr 8:31,201,709...31,234,217
JBrowse link
G BECN1 beclin 1 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G GBA glucosylceramidase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5501380|PMID:23707074) MGI
Ensembl
PMID:23707074 GO_REF:0000107 MGI:5501380 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta involved_in ISO (PMID:28017329) UniProt PMID:28017329 NCBI chr 5:65,669,553...65,683,445 JBrowse link
G PHB2 prohibitin 2 involved_in ISO (PMID:28017329)
(MGI:6436385|PMID:28017329)
UniProt PMID:28017329 MGI:6436385 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in
ISO (MGI:5603233|PMID:24949970)
(PMID:28017329)
MGI
UniProt
PMID:24949970 PMID:28017329 MGI:5603233 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G RETREG1 reticulophagy regulator 1 acts_upstream_of_or_within ISO (MGI:6370289|PMID:31446166) MGI PMID:31446166 MGI:6370289 NCBI chr 4:86,817,391...86,921,119 JBrowse link
G SQSTM1 sequestosome 1 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:33096711)
(MGI:6450300|PMID:25919711)
UniProt PMID:25919711 PMID:33096711 MGI:6450300 NCBI chr  X:122,111,608...122,125,714
Ensembl chr  X:122,111,434...122,125,506
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chr26:968,714...982,244
Ensembl chr26:970,138...982,229
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr 6:31,560,940...31,757,100
Ensembl chr 6:31,562,834...31,757,678
JBrowse link
G RNF41 ring finger protein 41 acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr10:512,650...521,293
Ensembl chr10:514,635...542,395
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332
JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chr26:17,918,852...17,981,947
Ensembl chr26:17,919,512...17,981,846
JBrowse link
negative regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VPS13C vacuolar protein sorting 13 homolog C involved_in ISO (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chr30:26,600,181...26,776,347
Ensembl chr30:26,601,513...26,776,763
JBrowse link
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G MFN2 mitofusin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225
JBrowse link
G OPTN optineurin involved_in ISO (PMID:25294927) ParkinsonsUK-UCL PMID:25294927 NCBI chr 2:23,356,471...23,390,569
Ensembl chr 2:23,357,237...23,392,511
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:19029340) ParkinsonsUK-UCL PMID:19029340 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5298125|PMID:22020285) ParkinsonsUK-UCL PMID:22020285 MGI:5298125 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922
JBrowse link
pexophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PJVK pejvakin involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:22,080,574...22,087,537
Ensembl chr36:22,040,303...22,092,249
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr28:29,792,612...29,815,466
Ensembl chr28:29,792,777...29,815,138
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr26:15,337,718...15,349,993
Ensembl chr26:15,336,864...15,355,757
JBrowse link
G HTT huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in ISS GO_Central GO_REF:0000024 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G HTT huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G SESN2 sestrin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5444071|PMID:22958918) Ensembl
MGI
PMID:22958918 GO_REF:0000107 MGI:5444071 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492
JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25332431) MGI
Ensembl
PMID:25332431 GO_REF:0000107 NCBI chr 1:94,997,240...95,062,424
Ensembl chr 1:94,997,290...95,064,468
JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25332431) MGI
Ensembl
PMID:25332431 GO_REF:0000107 NCBI chr 8:50,291,797...50,401,202
Ensembl chr 8:50,271,010...50,401,313
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS1 ceramide synthase 1 involved_in ISO (PMID:22922758) UniProt PMID:22922758 NCBI chr20:44,216,568...44,231,820 JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:28608965 RGD:13432560 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr16:45,454,660...45,458,606
Ensembl chr16:45,411,810...45,542,162
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:91,523,649...91,526,447
Ensembl chr  X:91,523,643...91,526,479
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chr 2:83,898,620...84,132,453
Ensembl chr 2:83,901,018...84,132,529
JBrowse link
positive regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,727,702...50,738,197
Ensembl chr20:50,727,749...50,736,269
JBrowse link
G HDAC6 histone deacetylase 6 involved_in ISO (MGI:5616310|PMID:20457763) ParkinsonsUK-UCL PMID:20457763 MGI:5616310 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) CACAO PMID:30217973 NCBI chr  X:45,234,666...45,409,641
Ensembl chr  X:45,234,322...45,410,043
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:20457763)
(PMID:20871098), (PMID:23212910)
ParkinsonsUK-UCL PMID:20457763 PMID:20871098 PMID:23212910 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr14:36,523,707...36,532,180
Ensembl chr14:36,523,707...36,532,291
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:23245322) GO_Central PMID:23245322 NCBI chr 9:55,855,576...55,894,915
Ensembl chr 9:55,856,091...55,894,488
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5299952|PMID:22033934) Ensembl
MGI
PMID:22033934 GO_REF:0000107 MGI:5299952 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G OPTN optineurin involved_in ISO (PMID:21617041) ParkinsonsUK-UCL PMID:21617041 NCBI chr 2:23,356,471...23,390,569
Ensembl chr 2:23,357,237...23,392,511
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333
JBrowse link
G TBK1 TANK binding kinase 1 involved_in ISO (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
reticulophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG2B autophagy related 2B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:65,039,960...65,110,811
Ensembl chr 8:65,044,194...65,110,796
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157
JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:6323456|PMID:31006538)
GO_Central
MGI
PMID:21873635 PMID:31006538 MGI:6323456 NCBI chr29:4,445,668...4,544,223
Ensembl chr29:4,375,785...4,517,168
JBrowse link
G RETREG1 reticulophagy regulator 1 involved_in ISO (PMID:26040720)
(MGI:5646045|PMID:26040720)
GO_Central PMID:26040720 MGI:5646045 NCBI chr 4:86,817,391...86,921,119 JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072
JBrowse link
G TEX264 testis expressed 264, ER-phagy receptor acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:31006538)
(PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:31006538 NCBI chr20:37,928,952...37,959,382
Ensembl chr20:37,928,953...37,955,993
JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:29,645,755...29,658,587
Ensembl chr23:29,645,966...29,659,019
JBrowse link
G UFC1 ubiquitin-fold modifier conjugating enzyme 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,319,039...21,339,524
Ensembl chr38:21,319,054...21,340,211
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr12:54,988,200...55,023,414
Ensembl chr12:54,988,264...55,021,626
JBrowse link
G UFM1 ubiquitin fold modifier 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr25:2,427,521...2,547,449
Ensembl chr25:2,386,609...2,547,311
JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:40,355,070...40,437,758
Ensembl chr 5:40,354,263...40,435,747
JBrowse link
xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG16L1 autophagy related 16 like 1 acts_upstream_of_or_within ISO (MGI:5605433|PMID:24954904) MGI PMID:24954904 MGI:5605433 NCBI chr25:44,761,034...44,800,033
Ensembl chr25:44,761,185...44,798,672
JBrowse link
G CALCOCO2 calcium binding and coiled-coil domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:25,050,603...25,078,147
Ensembl chr 9:25,050,690...25,077,557
JBrowse link
G LGALS8 galectin 8 involved_in ISO (PMID:22246324), (PMID:28077878) GO_Central PMID:22246324 PMID:28077878 NCBI chr 4:3,548,066...3,581,382
Ensembl chr 4:3,533,200...3,567,311
JBrowse link
G WIPI2 WD repeat domain, phosphoinositide interacting 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5605433|PMID:24954904) Ensembl
MGI
PMID:24954904 GO_REF:0000107 MGI:5605433 NCBI chr 6:12,656,469...12,698,623
Ensembl chr 6:12,658,239...12,698,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13872
    cellular process 13110
      process utilizing autophagic mechanism 403
        autophagy 403
          macroautophagy 225
            selective autophagy 70
              aggrephagy + 10
              glycophagy 2
              lipophagy + 7
              lysophagy 0
              mitophagy + 32
              pexophagy 1
              reticulophagy + 11
              ribophagy 0
              xenophagy + 12
Path 2
Term Annotations click to browse term
  biological_process 13872
    metabolic process 8970
      catabolic process 2005
        cellular catabolic process 1747
          autophagy 403
            macroautophagy 225
              selective autophagy 70
                aggrephagy + 10
                glycophagy 2
                lipophagy + 7
                lysophagy 0
                mitophagy + 32
                pexophagy 1
                reticulophagy + 11
                ribophagy 0
                xenophagy + 12
paths to the root