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ONTOLOGY REPORT - ANNOTATIONS


Term:selective autophagy
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Accession:GO:0061912 term browser browse the term
Definition:The macroautophagy process in which specific structures are targeted by the autophagy process.


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selective autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SQSTM1 sequestosome 1 involved_in ISO (PMID:22622177) UniProt PMID:22622177 NCBI chr 5:174,960,727...174,989,946
Ensembl chr 5:182,284,436...182,299,093
JBrowse link
aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACBD5 acyl-CoA binding domain containing 5 NOT|involved_in ISO (PMID:24535825) UniProt PMID:24535825 NCBI chr10:27,292,094...27,351,332
Ensembl chr10:27,666,395...27,711,423
JBrowse link
G ATG5 autophagy related 5 involved_in ISO (PMID:22982048)
(MGI:5751672|PMID:22982048)
ParkinsonsUK-UCL PMID:22982048 MGI:5751672 NCBI chr 6:103,997,824...104,140,931
Ensembl chr 6:107,871,208...108,013,807
JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chr 1:217,558,010...217,562,485
Ensembl chr 1:222,537,401...222,541,244
JBrowse link
G SQSTM1 sequestosome 1 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chr 5:174,960,727...174,989,946
Ensembl chr 5:182,284,436...182,299,093
JBrowse link
G UBQLN1 ubiquilin 1 involved_in ISO (PMID:21143716) UniProt PMID:21143716 NCBI chr 9:41,170,416...41,218,656
Ensembl chr 9:82,597,507...82,645,587
JBrowse link
G WDFY3 WD repeat and FYVE domain containing 3 involved_in ISO (PMID:20168092), (PMID:20417604) UniProt PMID:20168092 PMID:20417604 NCBI chr 4:39,215,474...39,511,870
Ensembl chr 4:45,170,700...45,361,599
JBrowse link
G WDR81 WD repeat domain 81 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chr17:1,708,119...1,722,405
Ensembl chr17:1,594,162...1,616,138
JBrowse link
glycophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STBD1 starch binding domain 1 involved_in ISO (PMID:20810658) GO_Central PMID:20810658 NCBI chr 4:47,889,830...47,894,943
Ensembl chr 4:53,729,242...53,734,492
JBrowse link
lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor involved_in ISO (PMID:29902443) UniProt PMID:29902443 NCBI chr2A:74,593,260...74,596,372
Ensembl chr2A:76,099,634...76,102,464
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISO (MGI:5689086|PMID:23708524) GO_Central PMID:23708524 MGI:5689086 NCBI chr 3:125,784,604...125,873,051 JBrowse link
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:25215947)
(PMID:21753002)
ParkinsonsUK-UCL PMID:21753002 PMID:25215947 NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205
JBrowse link
G ATG13 autophagy related 13 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chr11:46,567,728...46,623,609
Ensembl chr11:47,126,380...47,182,850
JBrowse link
G ATG14 autophagy related 14 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chr14:35,953,228...35,998,650
Ensembl chr14:54,226,720...54,272,018
JBrowse link
G BECN1 beclin 1 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta involved_in ISO (PMID:28017329) UniProt PMID:28017329 NCBI chr16:68,063,869...68,076,772 JBrowse link
G PHB2 prohibitin 2 involved_in ISO (PMID:28017329)
(MGI:6436385|PMID:28017329)
UniProt PMID:28017329 MGI:6436385 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
ISO (PMID:28017329)
(MGI:5603233|PMID:24949970)
UniProt
MGI
PMID:24949970 PMID:28017329 MGI:5603233 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G RETREG1 reticulophagy regulator 1 acts_upstream_of_or_within ISO (MGI:6370289|PMID:31446166) MGI PMID:31446166 MGI:6370289 NCBI chr 5:16,774,596...16,920,948 JBrowse link
G SQSTM1 sequestosome 1 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr 5:174,960,727...174,989,946
Ensembl chr 5:182,284,436...182,299,093
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:33096711)
(MGI:6450300|PMID:25919711)
UniProt PMID:25919711 PMID:33096711 MGI:6450300 NCBI chr  X:143,853,054...143,863,491
Ensembl chr  X:153,725,294...153,734,046
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chr12:129,549,399...129,579,087 JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512
JBrowse link
G RNF41 ring finger protein 41 acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr12:32,693,349...32,710,866
Ensembl chr12:32,944,814...32,962,584
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chr12:106,629,106...106,664,512
Ensembl chr12:110,022,959...110,058,335
JBrowse link
negative regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTRA2 HtrA serine peptidase 2 involved_in ISO (MGI:5581539|PMID:24709290) ParkinsonsUK-UCL PMID:24709290 MGI:5581539 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VPS13C vacuolar protein sorting 13 homolog C involved_in ISO (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chr15:40,819,512...41,020,644
Ensembl chr15:59,119,001...59,319,619
JBrowse link
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
G MFN2 mitofusin 2 involved_in ISO (MGI:5498413|PMID:23620051) ParkinsonsUK-UCL PMID:23620051 MGI:5498413 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077
JBrowse link
G OPTN optineurin involved_in ISO (PMID:25294927) ParkinsonsUK-UCL PMID:25294927 NCBI chr10:13,104,335...13,142,725
Ensembl chr10:13,077,345...13,115,773
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:19029340) ParkinsonsUK-UCL PMID:19029340 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5298125|PMID:22020285) ParkinsonsUK-UCL PMID:22020285 MGI:5298125 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
pexophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PJVK pejvakin involved_in ISO (MGI:6294584|PMID:30936319) UniProt PMID:30936319 MGI:6294584 NCBI chr2B:65,708,635...65,725,766
Ensembl chr2B:183,413,265...183,423,224
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr10:116,221,747...116,248,692
Ensembl chr10:119,643,963...119,665,964
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr12:116,758,785...116,774,883
Ensembl chr12:120,136,986...120,153,102
JBrowse link
G HTT huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in ISO (PMID:23708524) GO_Central PMID:23708524 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G HTT huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730
JBrowse link
G SESN2 sestrin 2 acts_upstream_of_or_within ISO (MGI:5444071|PMID:22958918) MGI PMID:22958918 MGI:5444071 NCBI chr 1:27,518,248...27,541,264
Ensembl chr 1:28,555,072...28,577,931
JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS1 ceramide synthase 1 involved_in ISO (PMID:22922758) UniProt PMID:22922758 NCBI chr19:18,308,265...18,334,892 JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:28608965 RGD:13432560 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:108,501,654...108,504,591
Ensembl chr  X:118,926,743...118,929,624
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chr 1:10,978,555...11,260,839
Ensembl chr 1:12,197,389...12,476,612
JBrowse link
positive regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chr19:9,942,644...9,955,112
Ensembl chr19:10,606,246...10,618,702
JBrowse link
G HDAC6 histone deacetylase 6 involved_in ISO (MGI:5616310|PMID:20457763) ParkinsonsUK-UCL PMID:20457763 MGI:5616310 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) CACAO PMID:30217973 NCBI chr  X:45,746,228...45,897,250
Ensembl chr  X:53,855,404...54,005,366
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:20457763)
(PMID:20871098), (PMID:23212910)
ParkinsonsUK-UCL PMID:20457763 PMID:20871098 PMID:23212910 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:23,501,438...23,511,321
Ensembl chr 7:23,112,630...23,122,195
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:23245322) GO_Central PMID:23245322 NCBI chr 9:98,571,796...98,623,581
Ensembl chr 9:127,245,508...127,297,645
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G OPTN optineurin involved_in ISO (PMID:21617041) ParkinsonsUK-UCL PMID:21617041 NCBI chr10:13,104,335...13,142,725
Ensembl chr10:13,077,345...13,115,773
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268
JBrowse link
G TBK1 TANK binding kinase 1 involved_in ISO (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chr12:24,419,271...24,469,164
Ensembl chr12:24,917,246...24,968,587
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
reticulophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDRGK1 DDRGK domain containing 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789
JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 acts_upstream_of_or_within ISO (MGI:6323456|PMID:31006538) MGI PMID:31006538 MGI:6323456 NCBI chr 8:49,046,830...49,138,795
Ensembl chr 8:46,430,131...46,521,722
JBrowse link
G RETREG1 reticulophagy regulator 1 involved_in ISO (PMID:26040720)
(MGI:5646045|PMID:26040720)
GO_Central PMID:26040720 MGI:5646045 NCBI chr 5:16,774,596...16,920,948 JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (MGI:5925643|PMID:29056340) UniProt PMID:29056340 MGI:5925643 NCBI chr 5:134,845,689...134,852,938
Ensembl chr 5:140,967,399...140,973,846
JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr 3:129,732,314...129,752,579
Ensembl chr 3:137,209,715...137,227,147
JBrowse link
G UFC1 ubiquitin-fold modifier conjugating enzyme 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr 1:136,545,095...136,571,327
Ensembl chr 1:140,479,007...140,484,143
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr 6:94,356,440...94,389,920
Ensembl chr 6:98,242,756...98,274,377
JBrowse link
G UFM1 ubiquitin fold modifier 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr13:19,571,114...19,584,259
Ensembl chr13:38,162,598...38,175,814
JBrowse link
xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG16L1 autophagy related 16 like 1 acts_upstream_of_or_within ISO (MGI:5605433|PMID:24954904) MGI PMID:24954904 MGI:5605433 NCBI chr2B:120,479,534...120,523,563
Ensembl chr2B:239,392,990...239,436,766
JBrowse link
G CALCOCO2 calcium binding and coiled-coil domain 2 involved_in ISO (PMID:25771791) GO_Central PMID:25771791 NCBI chr17:8,671,682...8,705,625
Ensembl chr17:8,858,872...8,891,276
JBrowse link
G LGALS8 galectin 8 involved_in ISO (PMID:22246324), (PMID:28077878) GO_Central PMID:22246324 PMID:28077878 NCBI chr 1:212,083,584...212,112,182 JBrowse link
G WIPI2 WD repeat domain, phosphoinositide interacting 2 acts_upstream_of_or_within ISO (MGI:5605433|PMID:24954904) MGI PMID:24954904 MGI:5605433 NCBI chr 7:5,446,621...5,488,170
Ensembl chr 7:5,467,334...5,510,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12652
    cellular process 11786
      process utilizing autophagic mechanism 373
        autophagy 373
          macroautophagy 202
            selective autophagy 66
              aggrephagy + 10
              glycophagy 1
              lipophagy + 7
              lysophagy 0
              mitophagy + 31
              pexophagy 1
              reticulophagy + 8
              ribophagy 0
              xenophagy + 12
Path 2
Term Annotations click to browse term
  biological_process 12652
    metabolic process 7925
      catabolic process 1766
        cellular catabolic process 1530
          autophagy 373
            macroautophagy 202
              selective autophagy 66
                aggrephagy + 10
                glycophagy 1
                lipophagy + 7
                lysophagy 0
                mitophagy + 31
                pexophagy 1
                reticulophagy + 8
                ribophagy 0
                xenophagy + 12
paths to the root