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ONTOLOGY REPORT - ANNOTATIONS


Term:autophagosome-lysosome fusion
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Accession:GO:0061909 term browser browse the term
Definition:The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.
Synonyms:exact_synonym: autophagosome fusion;   autophagosome-vacuole fusion


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autophagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISO
ISS
(PMID:28325809)
GO_REF:0000024
RGD
UniProt
PMID:28325809 GO_REF:0000024 NCBI chr 4:140,837,745...140,881,866
Ensembl chr 4:140,837,745...140,881,865
JBrowse link
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO (PMID:30538141)
(MGI:6273736|PMID:30538141)
RGD PMID:30538141 MGI:6273736 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO
ISS
(MGI:6159303|PMID:29727621)
GO_REF:0000024
RGD
UniProt
PMID:29727621 GO_REF:0000024 MGI:6159303 NCBI chr17:85,533,056...85,748,843 JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO
ISS
(MGI:6159303|PMID:29727621)
GO_REF:0000024
RGD
UniProt
PMID:29727621 GO_REF:0000024 MGI:6159303 NCBI chr10:85,655,223...85,684,138
Ensembl chr10:85,658,324...85,684,138
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISO
ISS
(PMID:28325809)
GO_REF:0000024
RGD
UniProt
PMID:28325809 GO_REF:0000024 NCBI chr10:91,451,890...91,500,675
Ensembl chr10:91,451,865...91,500,661
JBrowse link
G Rubcnl rubicon like autophagy enhancer involved_in ISO
IBA
(PMID:28306502)
PMID:21873635
RGD PMID:28306502, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr15:57,065,512...57,109,197
Ensembl chr15:57,065,428...57,102,599
JBrowse link
G Vps39 VPS39 subunit of HOPS complex involved_in ISO
IEA
(PMID:33422265)
GO_REF:0000107
RGD
Ensembl
PMID:33422265 GO_REF:0000107 NCBI chr 3:112,087,213...112,125,307
Ensembl chr 3:112,087,677...112,125,318
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      vesicle-mediated transport 1686
        vesicle fusion 110
          autophagosome-lysosome fusion 8
Path 2
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      cellular component organization or biogenesis 6829
        cellular component organization 6576
          membrane organization 885
            membrane fusion 168
              organelle membrane fusion 115
                vesicle fusion 110
                  autophagosome-lysosome fusion 8
paths to the root