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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial acetyl-CoA biosynthetic process from pyruvate
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Accession:GO:0061732 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.
Synonyms:xref: Reactome:R-HSA-372342.1;   Reactome:R-HSA-71397.1


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mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpc1 mitochondrial pyruvate carrier 1 ISO (MGI:MGI:5428352|PMID:22628558) MGI PMID:22628558 MGI:MGI:5428352 NCBI chrNW_004955439:15,515,966...15,531,618
Ensembl chrNW_004955439:15,516,090...15,531,116
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 ISO (MGI:MGI:5428352|PMID:22628558)
(MGI:MGI:5576400|PMID:24910426)
MGI PMID:22628558, PMID:24910426 MGI:MGI:5428352, MGI:MGI:5576400 NCBI chrNW_004955462:9,177,484...9,193,646 JBrowse link
G Pdha1 pyruvate dehydrogenase E1 alpha 1 subunit ISO (MGI:MGI:3817854|PMID:18586888) MGI PMID:18586888 MGI:MGI:3817854 NCBI chrNW_004955586:98,492...114,927
Ensembl chrNW_004955586:97,172...114,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7610
      organic substance metabolic process 7321
        thioester metabolic process 61
          acyl-CoA metabolic process 61
            acetyl-CoA metabolic process 30
              acetyl-CoA biosynthetic process 16
                acetyl-CoA biosynthetic process from pyruvate 11
                  mitochondrial acetyl-CoA biosynthetic process from pyruvate 3
Path 2
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7610
      cellular metabolic process 7025
        cellular aromatic compound metabolic process 3735
          nucleobase-containing compound metabolic process 3563
            nucleobase-containing small molecule metabolic process 356
              nucleoside phosphate metabolic process 311
                nucleotide metabolic process 301
                  ribonucleotide metabolic process 243
                    purine ribonucleotide metabolic process 236
                      purine ribonucleotide biosynthetic process 105
                        acyl-CoA biosynthetic process 23
                          acetyl-CoA biosynthetic process 16
                            acetyl-CoA biosynthetic process from pyruvate 11
                              mitochondrial acetyl-CoA biosynthetic process from pyruvate 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.