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ONTOLOGY REPORT - ANNOTATIONS


Term:spontaneous neurotransmitter secretion
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Accession:GO:0061669 term browser browse the term
Definition:Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.
Synonyms:exact_synonym: stimulus-independent neurotransmitter secretion


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spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOC2A double C2 domain alpha IEA Ensembl GO_REF:0000107 NCBI chr16:30,005,514...30,023,280
Ensembl chr16:30,005,514...30,023,270
JBrowse link
G DOC2B double C2 domain beta IEA Ensembl GO_REF:0000107 NCBI chr17:142,789...181,650
Ensembl chr17:142,789...181,650
JBrowse link
G DOC2GP double C2 domain gamma, pseudogene ISO (MGI:MGI:5141208|PMID:21521611) MGI PMID:21521611 MGI:MGI:5141208 NCBI chr11:67,613,524...67,615,664
Ensembl chr11:67,612,651...67,616,257
JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 ISO (MGI:MGI:4887275|PMID:21262469) ParkinsonsUK-UCL PMID:21262469 MGI:MGI:4887275 NCBI chr 6:71,886,703...72,403,145
Ensembl chr 6:71,886,703...72,403,143
JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 ISS ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 8:103,499,934...104,256,094
Ensembl chr 8:103,500,696...104,256,094
JBrowse link
G RPH3A rabphilin 3A IEA Ensembl GO_REF:0000107 NCBI chr12:112,575,236...112,898,881
Ensembl chr12:112,570,380...112,898,881
JBrowse link
G STX1B syntaxin 1B IEA Ensembl GO_REF:0000107 NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
JBrowse link
G SYT1 synaptotagmin 1 IEA Ensembl GO_REF:0000107 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
JBrowse link
G UNC13B unc-13 homolog B ISO PMID:21262469 ParkinsonsUK-UCL PMID:21262469 RGD:10047275 NCBI chr 9:35,162,009...35,405,338
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R9A protein phosphatase 1 regulatory subunit 9A IEA Ensembl GO_REF:0000107 NCBI chr 7:94,907,202...95,296,415
Ensembl chr 7:94,907,202...95,296,415
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IMP (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STX1B syntaxin 1B IEA Ensembl GO_REF:0000107 NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    biological regulation 13309
      regulation of biological quality 4612
        regulation of neurotransmitter levels 285
          neurotransmitter secretion 218
            spontaneous neurotransmitter secretion 11
              negative regulation of spontaneous neurotransmitter secretion 2
              positive regulation of spontaneous neurotransmitter secretion 1
              regulation of spontaneous neurotransmitter secretion + 3
Path 2
Term Annotations click to browse term
  biological_process 18670
    cellular process 17687
      cell communication 7246
        cell-cell signaling 2063
          synaptic signaling 995
            trans-synaptic signaling 967
              anterograde trans-synaptic signaling 958
                chemical synaptic transmission 958
                  spontaneous synaptic transmission 17
                    spontaneous neurotransmitter secretion 11
                      negative regulation of spontaneous neurotransmitter secretion 2
                      positive regulation of spontaneous neurotransmitter secretion 1
                      regulation of spontaneous neurotransmitter secretion + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.