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ONTOLOGY REPORT - ANNOTATIONS


Term:spontaneous neurotransmitter secretion
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Accession:GO:0061669 term browser browse the term
Definition:Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.
Synonyms:exact_synonym: stimulus-independent neurotransmitter secretion


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spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOC2A double C2 domain alpha IEA Ensembl GO_REF:0000107 NCBI chr 6:18,041,551...18,046,779
Ensembl chr 6:18,041,296...18,046,265
JBrowse link
G DOC2B double C2 domain beta IEA Ensembl GO_REF:0000107 NCBI chr 9:45,450,270...45,488,638
Ensembl chr 9:45,450,302...45,485,247
JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 ISO (MGI:MGI:4887275|PMID:21262469) ParkinsonsUK-UCL PMID:21262469 MGI:MGI:4887275 NCBI chr12:34,473,974...34,661,893
Ensembl chr12:34,474,033...34,659,410
JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 ISO (MGI:MGI:4887275|PMID:21262469) ParkinsonsUK-UCL PMID:21262469 MGI:MGI:4887275 NCBI chr13:4,928,518...5,499,258
Ensembl chr13:4,927,121...5,496,629
JBrowse link
G RPH3A rabphilin 3A IEA Ensembl GO_REF:0000107 NCBI chr26:10,147,910...10,379,742
Ensembl chr26:10,280,850...10,378,061
JBrowse link
G STX1B syntaxin 1B IEA Ensembl GO_REF:0000107 NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363
JBrowse link
G SYT1 synaptotagmin 1 IEA Ensembl GO_REF:0000107 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732
JBrowse link
G UNC13B unc-13 homolog B ISO PMID:21262469 ParkinsonsUK-UCL PMID:21262469 RGD:10047275 NCBI chr11:51,707,968...51,941,148 JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:16899074 RGD:10002752 NCBI chr14:20,251,791...20,563,315
Ensembl chr14:20,251,738...20,557,208
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STX1B syntaxin 1B IEA Ensembl GO_REF:0000107 NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    biological regulation 11555
      regulation of biological quality 4008
        regulation of neurotransmitter levels 258
          neurotransmitter secretion 193
            spontaneous neurotransmitter secretion 10
              negative regulation of spontaneous neurotransmitter secretion 2
              positive regulation of spontaneous neurotransmitter secretion 1
              regulation of spontaneous neurotransmitter secretion + 3
Path 2
Term Annotations click to browse term
  biological_process 16187
    cellular process 15465
      cell communication 6075
        cell-cell signaling 1615
          synaptic signaling 864
            trans-synaptic signaling 839
              anterograde trans-synaptic signaling 830
                chemical synaptic transmission 830
                  spontaneous synaptic transmission 16
                    spontaneous neurotransmitter secretion 10
                      negative regulation of spontaneous neurotransmitter secretion 2
                      positive regulation of spontaneous neurotransmitter secretion 1
                      regulation of spontaneous neurotransmitter secretion + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.