Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:determination of heart left/right asymmetry
go back to main search page
Accession:GO:0061371 term browser browse the term
Definition:Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
Synonyms:exact_synonym: determination of cardiac left/right asymmetry



show annotations for term's descendants           Sort by:
 
determination of heart left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2176158 (MGI:3574743|PMID:15750185) RGD PMID:15750185 MGI:3574743 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA
ISO
PMID:21873635
(MGI:3055649|PMID:15466485)
RGD PMID:15466485 PMID:21873635 MGI:3055649, RGD:13792537 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO (MGI:1927045|PMID:11076684) RGD PMID:11076684 MGI:1927045 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_or_within ISO MGI:1857639 (MGI:1203269|PMID:9576835) RGD PMID:9576835 MGI:1203269 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:3722325 (MGI:3839019|PMID:18043505)
GO_REF:0000024
(PMID:23063620)
Ensembl
RGD
UniProt
PMID:18043505 PMID:23063620 GO_REF:0000024 GO_REF:0000107 MGI:3839019 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613
JBrowse link
G Mmp21 matrix metallopeptidase 21 involved_in ISO (MGI:5700258|PMID:26437028) RGD PMID:26437028 MGI:5700258 NCBI chr 1:188,480,186...188,485,855
Ensembl chr 1:188,480,186...188,485,855
JBrowse link
G Odad3 outer dynein arm docking complex subunit 3 acts_upstream_of_or_within ISO MGI:5445347 (MGI:5607335|PMID:25192045) RGD PMID:25192045 MGI:5607335 NCBI chr 8:20,520,898...20,534,499
Ensembl chr 8:20,520,898...20,534,499
JBrowse link
G Tbxt T-box transcription factor T acts_upstream_of_or_within ISO MGI:1856184 (MGI:1328649|PMID:10349618) RGD PMID:10349618 MGI:1328649 NCBI chr 1:52,298,099...52,309,813
Ensembl chr 1:52,298,099...52,305,864
JBrowse link
heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ahi1 Abelson helper integration site 1 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:F8W3V6 (MGI:5306539|PMID:21959375)
UniProt
RGD
PMID:21959375 GO_REF:0000024 MGI:5306539 NCBI chr 1:15,768,047...15,886,744
Ensembl chr 1:15,762,462...15,891,041
JBrowse link
G Aplnr apelin receptor involved_in ISO (MGI:5584055|PMID:23603510) RGD PMID:23603510 MGI:5584055 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Arl13b ADP-ribosylation factor like GTPase 13B acts_upstream_of_or_within ISO MGI:3578151 (MGI:5430243|PMID:22554696) RGD PMID:22554696 MGI:5430243 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISO (MGI:6717247|PMID:32179481) RGD PMID:32179481 MGI:6717247 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520
JBrowse link
G Ccdc103 coiled-coil domain containing 103 involved_in ISO (PMID:22581229) RGD PMID:22581229 NCBI chr10:87,846,327...87,849,959
Ensembl chr10:87,846,357...87,849,757
JBrowse link
G Ccdc39 coiled-coil domain containing 39 involved_in ISO (PMID:22693285) RGD PMID:22693285 NCBI chr 2:116,665,261...116,703,364
Ensembl chr 2:116,665,261...116,703,350
JBrowse link
G Ccdc40 coiled-coil domain containing 40 involved_in IBA
ISO
PMID:21873635
(PMID:22693285)
RGD PMID:22693285 PMID:21873635 RGD:13792537 NCBI chr10:104,486,748...104,527,284
Ensembl chr10:104,486,748...104,527,243
JBrowse link
G Cfc1 cripto, FRL-1, cryptic family 1 acts_upstream_of_or_within ISO MGI:2179530 (MGI:1346729|PMID:10521397) RGD PMID:10521397 MGI:1346729 NCBI chr 9:36,742,106...36,751,931
Ensembl chr 9:36,739,071...36,751,930
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2176158 (MGI:3574743|PMID:15750185) RGD PMID:15750185 MGI:3574743 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cluap1 clusterin associated protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:5523142 (MGI:5509110|PMID:23742838)
GO_REF:0000107
RGD
Ensembl
PMID:23742838 GO_REF:0000107 MGI:5509110 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO
IEA
(MGI:2661305|PMID:12730124)
GO_REF:0000107
RGD
Ensembl
PMID:12730124 GO_REF:0000107 MGI:2661305 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 involved_in ISO
IEA
(PMID:19944400), (PMID:19944405)
GO_REF:0000107
RGD
Ensembl
PMID:19944400 PMID:19944405 GO_REF:0000107 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313
JBrowse link
G Eng endoglin involved_in ISO (MGI:1337912|PMID:10348742), (MGI:4368063|PMID:19703439) RGD PMID:10348742 PMID:19703439 MGI:1337912 MGI:4368063 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:1857843 (MGI:1340887|PMID:10411502) RGD PMID:10411502 MGI:1340887 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:3055632 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:3052615|PMID:15310850) RGD PMID:15310850 MGI:3052615 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (MGI:1201220|PMID:9486664) RGD PMID:9486664 MGI:1201220 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO MGI:2153823 (MGI:1197800|PMID:9500551) RGD PMID:9500551 MGI:1197800 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857639 (MGI:892134|PMID:9171826)
Ensembl
RGD
PMID:9171826 GO_REF:0000107 MGI:892134 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2179429 (MGI:3607736|PMID:14659802)
Ensembl
RGD
PMID:14659802 GO_REF:0000107 MGI:3607736 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3829198 (MGI:3828200|PMID:18930042)
GO_REF:0000107
RGD
Ensembl
PMID:18930042 GO_REF:0000107 MGI:3828200 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (MGI:3579954|PMID:15930098) RGD PMID:15930098 MGI:3579954 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980
JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO MGI:3707373 (MGI:3703110|PMID:17027958) RGD PMID:17027958 MGI:3703110 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:5142377|PMID:11517919) RGD PMID:11517919 MGI:5142377 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Kdm2a lysine demethylase 2A acts_upstream_of_or_within ISO (MGI:5615026|PMID:25463925) RGD PMID:25463925 MGI:5615026 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787
JBrowse link
G Kif3a kinesin family member 3a acts_upstream_of_or_within ISO MGI:2181727 (MGI:1337724|PMID:10330409) RGD PMID:10330409 MGI:1337724 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191
JBrowse link
G Lbx1 ladybird homeobox 1 acts_upstream_of_or_within ISO MGI:2386948 (MGI:3628723|PMID:12522123) RGD PMID:12522123 MGI:3628723 NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(MGI:3830899|PMID:16680724)
UniProt
RGD
PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:1339460|PMID:10393122) RGD PMID:10393122 MGI:1339460 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:3603514 (MGI:3603078|PMID:16000382) RGD PMID:16000382 MGI:3603078 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:166,345,853...166,471,715
NCBI chr 1:166,491,721...166,530,575
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1927227 (MGI:3773736|PMID:16510504), (MGI:74918|PMID:7628699), (MGI:892786|PMID:9192865)
Ensembl
RGD
PMID:7628699 PMID:9192865 PMID:16510504 GO_REF:0000107 MGI:3773736 MGI:74918 MGI:892786 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:106676 (MGI:3624254|PMID:16496285) RGD PMID:16496285 MGI:3624254 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Notch1 notch receptor 1 involved_in ISO UniProtKB:O35516 (MGI:2661305|PMID:12730124) RGD PMID:12730124 MGI:2661305 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q01705 (MGI:2661305|PMID:12730124)
Ensembl
RGD
PMID:12730124 GO_REF:0000107 MGI:2661305 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Noto notochord homeobox acts_upstream_of_or_within ISO MGI:3053092 (MGI:5646191|PMID:17884984) RGD PMID:17884984 MGI:5646191 NCBI chr 4:117,961,163...117,965,402
Ensembl chr 4:117,961,163...117,965,402
JBrowse link
G Nphp3 nephrocystin 3 involved_in ISO (PMID:18371931), (PMID:20007846) RGD PMID:18371931 PMID:20007846 NCBI chr 8:104,621,908...104,662,383
Ensembl chr 8:104,621,864...104,662,383
JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO MGI:3777011 (MGI:3776202|PMID:17573777) RGD PMID:17573777 MGI:3776202 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:21719175) RGD PMID:21719175 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:1347695|PMID:10557208) RGD PMID:10557208 MGI:1347695 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5142377|PMID:11517919)
MGI:1857796 (MGI:1340887|PMID:10411502), (MGI:1346236|PMID:10500184)
Ensembl
RGD
PMID:10411502 PMID:10500184 PMID:11517919 GO_REF:0000107 MGI:1340887 MGI:1346236 MGI:5142377 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO MGI:108051 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smo smoothened, frizzled class receptor involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5142377|PMID:11517919)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11517919 GO_REF:0000024 GO_REF:0000107 MGI:5142377 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within
ISO (MGI:3716378|PMID:17655922)
MGI:2179440 (MGI:3716256|PMID:17610846)
RGD PMID:17610846 PMID:17655922 MGI:3716256 MGI:3716378 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2385465|MGI:2386742 (MGI:3603734|PMID:15929941) RGD PMID:15929941 MGI:3603734 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO MGI:2152962 (MGI:1339521|PMID:10385121) RGD PMID:10385121 MGI:1339521 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:3512046 (MGI:3604917|PMID:16155214) RGD PMID:16155214 MGI:3604917 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3604925|PMID:15843409)
MGI:3579849|MGI:3580099 (MGI:3578601|PMID:15843407), (MGI:3579960|PMID:15901664)
RGD PMID:15843407 PMID:15843409 PMID:15901664 PMID:21873635 MGI:3578601 MGI:3579960 MGI:3604925, RGD:13792537 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2655214|MGI:3769504 (MGI:3769096|PMID:17460765), (MGI:4412356|PMID:18723448)
RGD PMID:17460765 PMID:18723448 PMID:21873635 MGI:3769096 MGI:4412356, RGD:13792537 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx6 T-box transcription factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4343479|MGI:4456438 (MGI:4453264|PMID:20178780) RGD PMID:20178780 MGI:4453264 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO (MGI:2157686|PMID:11440971) RGD PMID:11440971 MGI:2157686 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:1857489 (MGI:3611726|PMID:16291790) RGD PMID:16291790 MGI:3611726 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1298218 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Zic3 Zic family member 3 involved_in
acts_upstream_of_or_within
ISO (PMID:9354794)
MGI:2180720|MGI:3043027|MGI:97359 (MGI:3056222|PMID:15384171), (MGI:3624254|PMID:16496285)
RGD PMID:9354794 PMID:15384171 PMID:16496285 MGI:3056222 MGI:3624254 NCBI chr  X:136,123,662...136,134,295
Ensembl chr  X:136,124,026...136,134,746
JBrowse link
negative regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3039059|PMID:15042700) RGD PMID:15042700 MGI:3039059 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      anatomical structure development 6368
        animal organ development 4163
          heart development 716
            determination of heart left/right asymmetry 68
              heart jogging + 0
              heart looping + 62
Path 2
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      anatomical structure development 6368
        multicellular organism development 5437
          pattern specification process 501
            specification of symmetry 144
              determination of bilateral symmetry 143
                determination of left/right symmetry 135
                  determination of heart left/right asymmetry 68
                    heart jogging + 0
                    heart looping + 62
paths to the root