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ONTOLOGY REPORT - ANNOTATIONS


Term:testosterone biosynthetic process
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Accession:GO:0061370 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.


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testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) involved_in ISO (PMID:16983398) UniProt PMID:16983398 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:19883722 RGD:4145609 NCBI chr30:37,474,997...37,487,028
Ensembl chr30:37,473,901...37,487,507
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 acts_upstream_of_or_within ISO (MGI:1261712|PMID:9618522) MGI PMID:9618522 MGI:1261712 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353
JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in IEA
ISO
Ensembl
RGD
PMID:8612487 GO_REF:0000107 RGD:728619 NCBI chr 9:20,402,124...20,407,143
Ensembl chr 9:20,405,019...20,406,792
JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:70,551,013...70,586,364
Ensembl chr 1:70,487,334...70,586,368
JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:25,017,113...25,056,156
Ensembl chr17:25,017,113...25,056,544
JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:19883722 RGD:4145609 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,109,787...107,113,932
Ensembl chr 1:107,109,791...107,113,811
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:12949260)
(MGI:2675528|PMID:12949260)
UniProt PMID:12949260 MGI:2675528 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) involved_in ISO (PMID:19336506) UniProt PMID:19336506 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13872
    metabolic process 8970
      biosynthetic process 4582
        olefinic compound biosynthetic process 26
          testosterone biosynthetic process 10
            negative regulation of testosterone biosynthetic process 2
            regulation of testosterone biosynthetic process + 4
Path 2
Term Annotations click to browse term
  biological_process 13872
    metabolic process 8970
      primary metabolic process 7906
        lipid metabolic process 1092
          steroid metabolic process 254
            steroid biosynthetic process 133
              testosterone biosynthetic process 10
                negative regulation of testosterone biosynthetic process 2
                regulation of testosterone biosynthetic process + 4
paths to the root