Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:testosterone biosynthetic process
go back to main search page
Accession:GO:0061370 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.


show annotations for term's descendants           Sort by:
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:16983398) RGD PMID:16983398 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:19883722 RGD:4145609 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154536 (PMID:9618522)		 Ensembl
RGD		 PMID:9618522 GO_REF:0000107 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 involved_in IDA
ISO		 (MGI:1267145|PMID:9658408) RGD PMID:9658408 PMID:8612487 MGI:1267145, RGD:728619 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:16467141 RGD:4889544 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO (PMID:32274496) RGD PMID:32274496 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 involved_in ISO
ISS		 (PMID:10898110)
GO_REF:0000024		 RGD
UniProt		 PMID:10898110 GO_REF:0000024 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:19883722 RGD:4145609 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (MGI:3839065|PMID:18818293)
(PMID:18818293)		 RGD PMID:18818293 MGI:3839065 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:12949260)
(MGI:2675528|PMID:12949260)		 RGD PMID:12949260 MGI:2675528 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19336506) RGD PMID:19336506 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in ISO
ISS		 (MGI:4947864|PMID:21333348), (PMID:21333348)
GO_REF:0000024
(PMID:21333348)		 RGD
UniProt		 PMID:21333348 GO_REF:0000024 MGI:4947864 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISO (PMID:21333348) RGD PMID:21333348 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A involved_in ISO
ISS		 (MGI:4947864|PMID:21333348), (PMID:21333348)
(PMID:21333348)
GO_REF:0000024		 RGD
UniProt		 PMID:21333348 GO_REF:0000024 MGI:4947864 NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:22429315 RGD:7775068 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        biosynthetic process 8436
          olefinic compound biosynthetic process 35
            testosterone biosynthetic process 15
              negative regulation of testosterone biosynthetic process 2
              regulation of testosterone biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        primary metabolic process 10935
          lipid metabolic process 1457
            steroid metabolic process 370
              steroid biosynthetic process 198
                testosterone biosynthetic process 15
                  negative regulation of testosterone biosynthetic process 2
                  regulation of testosterone biosynthetic process + 7
paths to the root