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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in outflow tract morphogenesis
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Accession:GO:0061347 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.



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planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857617 (MGI:4830282|PMID:19056682)
Ensembl
RGD
PMID:19056682 GO_REF:0000107 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure morphogenesis 2925
        outflow tract morphogenesis 86
          planar cell polarity pathway involved in outflow tract morphogenesis 2
            negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 1
            regulation of planar cell polarity pathway involved in outflow tract morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        tissue development 2148
          epithelium development 1332
            morphogenesis of an epithelium 604
              morphogenesis of a polarized epithelium 88
                establishment of planar polarity 61
                  regulation of establishment of planar polarity 43
                    Wnt signaling pathway, planar cell polarity pathway 37
                      planar cell polarity pathway involved in heart morphogenesis 3
                        planar cell polarity pathway involved in outflow tract morphogenesis 2
                          negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 1
                          regulation of planar cell polarity pathway involved in outflow tract morphogenesis + 1
paths to the root