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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in heart morphogenesis
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Accession:GO:0061346 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.



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planar cell polarity pathway involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:5558098 (MGI:5544506|PMID:24302887) RGD PMID:24302887 MGI:5544506 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378
JBrowse link
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
planar cell polarity pathway involved in cardiac right atrium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure morphogenesis 2987
        animal organ morphogenesis 1182
          heart morphogenesis 288
            planar cell polarity pathway involved in heart morphogenesis 3
              negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
              planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 2
              planar cell polarity pathway involved in cardiac right atrium morphogenesis + 2
              planar cell polarity pathway involved in outflow tract morphogenesis + 2
              planar cell polarity pathway involved in pericardium morphogenesis + 2
              planar cell polarity pathway involved in ventricular septum morphogenesis + 2
              regulation of planar cell polarity pathway involved in heart morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        anatomical structure morphogenesis 2987
          tissue morphogenesis 722
            morphogenesis of an epithelium 601
              morphogenesis of a polarized epithelium 87
                establishment of planar polarity 60
                  regulation of establishment of planar polarity 42
                    Wnt signaling pathway, planar cell polarity pathway 37
                      planar cell polarity pathway involved in heart morphogenesis 3
                        negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
                        planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 2
                        planar cell polarity pathway involved in cardiac right atrium morphogenesis + 2
                        planar cell polarity pathway involved in outflow tract morphogenesis + 2
                        planar cell polarity pathway involved in pericardium morphogenesis + 2
                        planar cell polarity pathway involved in ventricular septum morphogenesis + 2
                        regulation of planar cell polarity pathway involved in heart morphogenesis + 1
paths to the root