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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac conduction
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Accession:GO:0061337 term browser browse the term
Definition:Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.



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cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 involved_in IMP (PMID:24439875) ARUK-UCL PMID:24439875 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:24728418) UniProt PMID:24728418 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10969038), (PMID:9109444) Ensembl
MGI
PMID:9109444 PMID:10969038 GO_REF:0000107 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:10515563), (PMID:10969038), (PMID:9501070)
(PMID:18599871), (PMID:9501069)
MGI PMID:9501069 PMID:9501070 PMID:10515563 PMID:10969038 PMID:18599871 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
G MEF2A myocyte enhancer factor 2A involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488
JBrowse link
G MIR208A microRNA 208a acts_upstream_of_or_within ISO (PMID:19726871) MGI PMID:19726871 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 acts_upstream_of_or_within ISO (PMID:20062061) MGI PMID:20062061 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in
acts_upstream_of_or_within_positive_effect
IEA
ISO
(PMID:27932425) Ensembl
MGI
PMID:27932425 GO_REF:0000107 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19351516) Ensembl
MGI
PMID:19351516 GO_REF:0000107 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SLC4A3 solute carrier family 4 member 3 acts_upstream_of_or_within IMP (PMID:29167417) ARUK-UCL PMID:29167417 NCBI chr 2:219,627,630...219,641,971
Ensembl chr 2:219,627,394...219,641,980
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:20877009) BHF-UCL
MGI
Ensembl
PMID:20877009 GO_REF:0000024 GO_REF:0000107 NCBI chr19:40,467,001...40,576,464
Ensembl chr19:40,466,241...40,576,464
JBrowse link
G TMEM65 transmembrane protein 65 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:124,306,189...124,372,701
Ensembl chr 8:124,306,189...124,372,701
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:27799555) Ensembl
MGI
PMID:27799555 GO_REF:0000107 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:17242276), (PMID:18832177), (PMID:21859974) BHF-UCL PMID:17242276 PMID:18832177 PMID:21859974 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in TAS (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJC1 gap junction protein gamma 1 involved_in TAS (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP (PMID:18313602) BHF-UCL PMID:18313602 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:12522251) BHF-UCL PMID:12522251 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
G NUP155 nucleoporin 155 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19070573) Ensembl
MGI
PMID:19070573 GO_REF:0000107 NCBI chr 5:37,288,137...37,371,106
Ensembl chr 5:37,288,137...37,371,106
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IMP (PMID:21051419) BHF-UCL PMID:21051419 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
atrial cardiac muscle cell to AV node cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
atrial cardiac muscle cell to AV node cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IMP
IEA
IBA
NAS
(PMID:16790700), (PMID:20606116), (PMID:23348765)
(PMID:15044680)
BHF-UCL
TreeGrafter
GO_Central
PMID:15044680 PMID:16790700 PMID:20606116 PMID:23348765 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IMP (PMID:24998131) BHF-UCL PMID:24998131 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IMP (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
AV node cell to bundle of His cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISS UniProt GO_REF:0000024 NCBI chr21:17,513,043...17,636,262
Ensembl chr21:17,513,043...17,593,579
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:10515563) MGI PMID:10515563 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:10471492) BHF-UCL PMID:10471492 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
AV node cell to bundle of His cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:22247482) BHF-UCL PMID:22247482 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJC1 gap junction protein gamma 1 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
G GJC3 gap junction protein gamma 3 NOT|involved_in NAS (PMID:21742272) BHF-UCL PMID:21742272 NCBI chr 7:99,923,266...99,930,747
Ensembl chr 7:99,923,266...99,929,620
JBrowse link
G GJD3 gap junction protein delta 3 NOT|involved_in IEP
IEA
(PMID:19168070) BHF-UCL
GOC
Ensembl
PMID:19168070 GO_REF:0000107 GO_REF:0000108 NCBI chr17:40,360,652...40,364,737
Ensembl chr17:40,360,652...40,364,737
JBrowse link
AV node cell to bundle of His cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
AV node cell-bundle of His cell adhesion involved in cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr21:17,513,043...17,636,262
Ensembl chr21:17,513,043...17,593,579
JBrowse link
bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IMP (PMID:24998131) BHF-UCL PMID:24998131 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
bundle of His cell to Purkinje myocyte communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGT-TNNI3K FPGT-TNNI3K readthrough involved_in IMP (PMID:23236294) BHF-UCL PMID:23236294 NCBI chr 1:74,198,242...74,544,428
Ensembl chr 1:74,198,235...74,544,393
JBrowse link
G TNNI3K TNNI3 interacting kinase involved_in IMP (PMID:23236294) BHF-UCL PMID:23236294 NCBI chr 1:74,235,387...74,544,428
Ensembl chr 1:74,235,387...74,544,428
JBrowse link
bundle of His cell to Purkinje myocyte communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IMP
ISS
(PMID:22247482) BHF-UCL PMID:22247482 GO_REF:0000024 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G TBX5 T-box transcription factor 5 involved_in
acts_upstream_of_positive_effect
IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr12:114,353,911...114,408,442
Ensembl chr12:114,353,911...114,408,442
JBrowse link
bundle of His cell-Purkinje myocyte adhesion involved in cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNA3 catenin alpha 3 involved_in IMP (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637
JBrowse link
G DSC2 desmocollin 2 involved_in IMP (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522
JBrowse link
G DSG2 desmoglein 2 involved_in IMP (PMID:16505173) BHF-UCL PMID:16505173 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G DSP desmoplakin involved_in IMP (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,338...7,586,714
JBrowse link
G JUP junction plakoglobin involved_in IMP (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
JBrowse link
cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in TAS (PMID:19683723) BHF-UCL PMID:19683723 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in TAS (PMID:19683723) BHF-UCL PMID:19683723 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 involved_in TAS (PMID:19683723) BHF-UCL PMID:19683723 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in TAS (PMID:19683723) BHF-UCL PMID:19683723 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 involved_in TAS (PMID:19683723) BHF-UCL PMID:19683723 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in TAS (PMID:11576544) BHF-UCL PMID:11576544 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in NAS (PMID:1696265) BHF-UCL PMID:1696265 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:16790700), (PMID:23348765)
(PMID:11046183)
BHF-UCL
MGI
PMID:11046183 PMID:16790700 PMID:23348765 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G PKP2 plakophilin 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in TAS (PMID:23507255) BHF-UCL PMID:23507255 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IC BHF-UCL GO_REF:0000036 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
cell communication involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO (PMID:32109384) MGI PMID:32109384 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:10747000) MGI PMID:10747000 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJD3 gap junction protein delta 3 NOT|involved_in IEP (PMID:19168070) BHF-UCL PMID:19168070 NCBI chr17:40,360,652...40,364,737
Ensembl chr17:40,360,652...40,364,737
JBrowse link
cell-cell signaling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKP2 plakophilin 2 involved_in IMP
IEA
(PMID:22889254) BHF-UCL
TreeGrafter
PMID:22889254 GO_REF:0000118 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
JBrowse link
G RNF207 ring finger protein 207 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:6,206,119...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
G TBX5 T-box transcription factor 5 involved_in
acts_upstream_of_positive_effect
IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr12:114,353,911...114,408,442
Ensembl chr12:114,353,911...114,408,442
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:26253506) BHF-UCL PMID:26253506 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IMP (PMID:21383000) BHF-UCL PMID:21383000 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IMP (PMID:18464934) BHF-UCL PMID:18464934 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:22766342) BHF-UCL PMID:22766342 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in TAS (PMID:19098452) BHF-UCL PMID:19098452 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21131953)
(PMID:12700358)
BHF-UCL
MGI
PMID:12700358 PMID:21131953 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:16407510) BHF-UCL PMID:16407510 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in ISS (PMID:19139040) BHF-UCL PMID:19139040 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:23264583) BHF-UCL PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP
TAS
(PMID:19343045)
(PMID:10820151)
BHF-UCL PMID:10820151 PMID:19343045 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
negative regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJD3 gap junction protein delta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,360,652...40,364,737
Ensembl chr17:40,360,652...40,364,737
JBrowse link
G MIR1-1 microRNA 1-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:62,554,306...62,554,376
Ensembl chr20:62,554,306...62,554,376
JBrowse link
G MIR1-2 microRNA 1-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:21,829,004...21,829,088
Ensembl chr18:21,829,004...21,829,088
JBrowse link
negative regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJD3 gap junction protein delta 3 involved_in
NOT|involved_in
IEA
IEP
(PMID:19168070) Ensembl
BHF-UCL
PMID:19168070 GO_REF:0000107 NCBI chr17:40,360,652...40,364,737
Ensembl chr17:40,360,652...40,364,737
JBrowse link
negative regulation of membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR328 microRNA 328 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr16:67,202,321...67,202,395
Ensembl chr16:67,202,321...67,202,395
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in ISO
ISS
RGD
BHF-UCL
PMID:23954346 GO_REF:0000024 RGD:10003031 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
positive regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TBX5 T-box transcription factor 5 acts_upstream_of
involved_in
ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:114,353,911...114,408,442
Ensembl chr12:114,353,911...114,408,442
JBrowse link
positive regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TBX5 T-box transcription factor 5 acts_upstream_of TAS (PMID:15289437) BHF-UCL PMID:15289437 NCBI chr12:114,353,911...114,408,442
Ensembl chr12:114,353,911...114,408,442
JBrowse link
G TRDN triadin involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 6:123,216,339...123,636,950
Ensembl chr 6:123,216,339...123,637,189
JBrowse link
Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in NAS (PMID:15044680) BHF-UCL PMID:15044680 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
Purkinje myocyte to ventricular cardiac muscle cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ2 calsequestrin 2 involved_in NAS (PMID:22198169) BHF-UCL PMID:22198169 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,884
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597) BHF-UCL PMID:12571597 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
regulation of AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (MGI:2449848|PMID:12571597) BHF-UCL PMID:12571597 MGI:2449848 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr21:17,513,043...17,636,262
Ensembl chr21:17,513,043...17,593,579
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:22247482) BHF-UCL PMID:22247482 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
regulation of bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:22247482) BHF-UCL PMID:22247482 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IMP (PMID:21621375) BHF-UCL PMID:21621375 NCBI chr17:8,288,670...8,290,087
Ensembl chr17:8,288,654...8,290,092
JBrowse link
regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IMP (PMID:12967627) BHF-UCL PMID:12967627 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G AGT angiotensinogen involved_in IGI (PMID:17416596) BHF-UCL PMID:17416596 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007
JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
JBrowse link
G CORIN corin, serine peptidase involved_in TAS Reactome Reactome:R-HSA-5578768 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106
JBrowse link
G EHD3 EH domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,234,152...31,269,451
Ensembl chr 2:31,234,152...31,269,451
JBrowse link
G FPGT-TNNI3K FPGT-TNNI3K readthrough involved_in IGI
IEA
(PMID:23236294) BHF-UCL
Ensembl
PMID:23236294 GO_REF:0000107 NCBI chr 1:74,198,242...74,544,428
Ensembl chr 1:74,198,235...74,544,393
JBrowse link
G MIR19A microRNA 19a involved_in IDA (PMID:23271053) BHF-UCL PMID:23271053 NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972
JBrowse link
G MIR208A microRNA 208a involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666
JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in ISS
IEA
(PMID:8900537) BHF-UCL
Ensembl
PMID:8900537 GO_REF:0000107 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G SLC8A2 solute carrier family 8 member A2 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr19:47,428,017...47,471,893
Ensembl chr19:47,428,017...47,471,893
JBrowse link
G SLC8A3 solute carrier family 8 member A3 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
JBrowse link
G TMEM65 transmembrane protein 65 involved_in ISS
IBA
IEA
UniProt
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:124,306,189...124,372,701
Ensembl chr 8:124,306,189...124,372,701
JBrowse link
G TNNI3K TNNI3 interacting kinase involved_in IGI
IEA
(PMID:23236294) BHF-UCL
Ensembl
PMID:23236294 GO_REF:0000107 NCBI chr 1:74,235,387...74,544,428
Ensembl chr 1:74,235,387...74,544,428
JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in TAS Reactome Reactome:R-HSA-5578775 NCBI chr 3:142,724,034...142,807,888
Ensembl chr 3:142,724,034...142,807,888
JBrowse link
regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in IC BHF-UCL GO_REF:0000036 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 involved_in IC BHF-UCL GO_REF:0000036 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921
JBrowse link
G CALM3 calmodulin 3 involved_in IC BHF-UCL GO_REF:0000036 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in IC (PMID:12676813) BHF-UCL PMID:12676813 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAV1 caveolin 1 involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G HRC histidine rich calcium binding protein involved_in IGI (PMID:24125847) BHF-UCL PMID:24125847 NCBI chr19:49,151,198...49,155,396
Ensembl chr19:49,151,198...49,155,396
JBrowse link
G IRX3 iroquois homeobox 3 acts_upstream_of
involved_in
ISS
IEA
(PMID:21825130) BHF-UCL
Ensembl
PMID:21825130 GO_REF:0000107 NCBI chr16:54,283,304...54,286,787
Ensembl chr16:54,283,304...54,286,787
JBrowse link
G PDE4D phosphodiesterase 4D involved_in IMP (PMID:16213210) BHF-UCL PMID:16213210 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G SRI sorcin involved_in IMP (PMID:17130302) BHF-UCL PMID:17130302 NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,115...88,226,993
JBrowse link
regulation of heart rate by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G AKAP9 A-kinase anchoring protein 9 involved_in IMP (PMID:18093912) BHF-UCL PMID:18093912 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673
JBrowse link
G ANK2 ankyrin 2 involved_in ISS
IMP
(PMID:12571597), (PMID:15178757), (PMID:17242276), (PMID:21859974) BHF-UCL PMID:12571597 PMID:15178757 PMID:17242276 PMID:21859974 GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G BIN1 bridging integrator 1 involved_in IEA
ISS
Ensembl
ARUK-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:15454078), (PMID:15863612), (PMID:17224476), (PMID:26253506) BHF-UCL PMID:15454078 PMID:15863612 PMID:17224476 PMID:26253506 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21131953)
(PMID:12700358)
BHF-UCL
MGI
PMID:12700358 PMID:21131953 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IMP (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in IC (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAV1 caveolin 1 involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CTNNA3 catenin alpha 3 involved_in IMP (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637
JBrowse link
G DSC2 desmocollin 2 involved_in IMP (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522
JBrowse link
G DSG2 desmoglein 2 involved_in IMP (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G DSP desmoplakin involved_in IMP (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,338...7,586,714
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:11046183) MGI PMID:11046183 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:12750403) BHF-UCL PMID:12750403 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of
IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G JUP junction plakoglobin involved_in IMP (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IMP (PMID:21349352) BHF-UCL PMID:21349352 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in
acts_upstream_of_or_within
IMP
ISO
IEA
IBA
(PMID:10400998)
(PMID:14561835)
BHF-UCL
MGI
TreeGrafter
GO_Central
Ensembl
PMID:10400998 PMID:14561835 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE1B potassium voltage-gated channel subfamily E regulatory subunit 1B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:7,816,677...7,829,632
Ensembl chr21:7,816,675...7,829,926
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP
IEA
IBA
(PMID:10219239) BHF-UCL
TreeGrafter
GO_Central
PMID:10219239 GO_REF:0000033 GO_REF:0000118 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP
IBA
IEA
(PMID:22987075) BHF-UCL
GO_Central
TreeGrafter
PMID:22987075 GO_REF:0000033 GO_REF:0000118 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP
IEA
IBA
(PMID:18313602), (PMID:21493962) BHF-UCL
TreeGrafter
GO_Central
PMID:18313602 PMID:21493962 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within
IMP
IEA
IBA
(PMID:21536673)
(PMID:7889573)
BHF-UCL
TreeGrafter
GO_Central
MGI
PMID:7889573 PMID:21536673 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr17:63,523,358...63,548,992
Ensembl chr17:63,523,334...63,548,977
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IMP (PMID:15761194) BHF-UCL PMID:15761194 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:17980246), (PMID:22889254) BHF-UCL PMID:17980246 PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IMP
IEA
IBA
(PMID:19808477) BHF-UCL
TreeGrafter
GO_Central
PMID:19808477 GO_REF:0000033 GO_REF:0000118 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IMP (PMID:19808477) BHF-UCL PMID:19808477 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IMP
IBA
(PMID:20042427), (PMID:21051419) BHF-UCL
GO_Central
PMID:20042427 PMID:21051419 GO_REF:0000033 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IMP (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21895525)
(PMID:11972032), (PMID:15809371), (PMID:15932895), (PMID:16172272)
BHF-UCL
MGI
PMID:11972032 PMID:15809371 PMID:15932895 PMID:16172272 PMID:21895525 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IC (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222
JBrowse link
regulation of membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR208A microRNA 208a involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666
JBrowse link
regulation of membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in IC BHF-UCL GO_REF:0000111 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
regulation of Purkinje myocyte action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:22247482) BHF-UCL PMID:22247482 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
regulation of SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597), (PMID:18832177) BHF-UCL PMID:12571597 PMID:18832177 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G TBX18 T-box transcription factor 18 acts_upstream_of IMP (PMID:23242162) BHF-UCL PMID:23242162 NCBI chr 6:84,732,496...84,764,598
Ensembl chr 6:84,687,351...84,764,598
JBrowse link
regulation of the force of heart contraction by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLN phospholamban involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10644605) Ensembl
MGI
PMID:10644605 GO_REF:0000107 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IMP (PMID:21359875) BHF-UCL PMID:21359875 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:11046183) MGI PMID:11046183 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:12750403) BHF-UCL PMID:12750403 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18616619) BHF-UCL PMID:18616619 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
SA node cell to atrial cardiac muscle cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597), (PMID:18832177), (PMID:21859974) BHF-UCL PMID:12571597 PMID:18832177 PMID:21859974 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
SA node cell to atrial cardiac muscle cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in NAS (PMID:15044680), (PMID:21357845) BHF-UCL PMID:15044680 PMID:21357845 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJC1 gap junction protein gamma 1 involved_in NAS (PMID:21357845) BHF-UCL PMID:21357845 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
SA node cell to atrial cardiac muscle cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    multicellular organismal process 8456
      system process 2748
        regulation of system process 737
          regulation of blood circulation 335
            regulation of heart contraction 255
              cardiac conduction 102
                cell communication involved in cardiac conduction + 60
                negative regulation of cardiac conduction 3
                positive regulation of cardiac conduction 1
                regulation of cardiac conduction + 30
                regulation of heart rate by cardiac conduction 42
                regulation of the force of heart contraction by cardiac conduction 2
Path 2
Term Annotations click to browse term
  biological_process 19669
    multicellular organismal process 8456
      system process 2748
        circulatory system process 735
          blood circulation 651
            heart contraction 302
              regulation of heart contraction 255
                cardiac conduction 102
                  cell communication involved in cardiac conduction + 60
                  negative regulation of cardiac conduction 3
                  positive regulation of cardiac conduction 1
                  regulation of cardiac conduction + 30
                  regulation of heart rate by cardiac conduction 42
                  regulation of the force of heart contraction by cardiac conduction 2
paths to the root