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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac conduction
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Accession:GO:0061337 term browser browse the term
Definition:Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.


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cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3639795|PMID:10969038), (MGI:86953|PMID:9109444) MGI
Ensembl
PMID:9109444 PMID:10969038 GO_REF:0000107 MGI:3639795 MGI:86953 NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070), (MGI:3639795|PMID:10969038), (MGI:3696497|PMID:10515563)
(MGI:1197847|PMID:9501069), (MGI:4412358|PMID:18599871)
MGI PMID:9501069 PMID:9501070 PMID:10515563 PMID:10969038 PMID:18599871 MGI:1197846 MGI:1197847 MGI:3639795 MGI:3696497 MGI:4412358
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863
JBrowse link
G MEF2A myocyte enhancer factor 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:18,150,315...18,312,975
Ensembl chr29:18,150,854...18,309,247
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr19:18,507,184...18,801,535 JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 acts_upstream_of_or_within ISO (MGI:4848026|PMID:20062061) MGI PMID:20062061 MGI:4848026 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 acts_upstream_of_or_within_positive_effect
involved_in
ISO
IEA
(MGI:6256920|PMID:27932425) MGI
Ensembl
PMID:27932425 GO_REF:0000107 MGI:6256920 NCBI chr 1:109,538,694...109,552,745
Ensembl chr 1:109,538,652...109,552,740
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5294649|PMID:19351516) MGI
Ensembl
PMID:19351516 GO_REF:0000107 MGI:5294649 NCBI chr 1:115,031,634...115,057,829
Ensembl chr 1:115,034,508...115,057,787
JBrowse link
G SLC4A3 solute carrier family 4 member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:29167417) ARUK-UCL
Ensembl
PMID:29167417 GO_REF:0000107 NCBI chr10:105,528,845...105,543,657
Ensembl chr10:105,529,093...105,543,405
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4837024|PMID:20877009) MGI
Ensembl
PMID:20877009 GO_REF:0000107 MGI:4837024 NCBI chr 6:34,926,413...35,036,611
Ensembl chr 6:34,930,519...35,035,719
JBrowse link
G TMEM65 transmembrane protein 65 involved_in ISO (MGI:7366463|PMID:36257954) UniProt PMID:36257954 MGI:7366463 NCBI chr 8:118,883,409...118,944,834 JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5824440|PMID:27799555) MGI
Ensembl
PMID:27799555 GO_REF:0000107 MGI:5824440 NCBI chr20:92,605,495...92,648,110
Ensembl chr20:92,605,309...92,648,114
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) BHF-UCL PMID:18313602 NCBI chr  X:97,477,667...97,485,376
Ensembl chr  X:97,478,562...97,478,987
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863
JBrowse link
G NUP155 nucleoporin 155 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3839697|PMID:19070573) MGI
Ensembl
PMID:19070573 GO_REF:0000107 MGI:3839697 NCBI chr 4:36,167,078...36,243,040 JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:115,031,634...115,057,829
Ensembl chr 1:115,034,508...115,057,787
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
atrial cardiac muscle cell to AV node cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (MGI:2449848|PMID:12571597) BHF-UCL PMID:12571597 MGI:2449848 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
atrial cardiac muscle cell to AV node cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,507,121...109,528,512
Ensembl chr 1:109,509,979...109,528,721
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
AV node cell to bundle of His cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISO (MGI:3814765|PMID:18636119) UniProt PMID:18636119 MGI:3814765 NCBI chr 2:75,027,499...75,078,206
Ensembl chr 2:75,001,562...75,078,033
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3696497|PMID:10515563) MGI PMID:10515563 MGI:3696497
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
AV node cell to bundle of His cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G GJC1 gap junction protein gamma 1 involved_in ISO (MGI:5544102|PMID:22982984) BHF-UCL PMID:22982984 MGI:5544102 NCBI chr16:61,575,851...61,596,488
Ensembl chr16:61,594,885...61,596,075
JBrowse link
G GJD3 gap junction protein delta 3 NOT|involved_in ISO
IEA
(PMID:19168070) BHF-UCL
Ensembl
PMID:19168070 GO_REF:0000107 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
JBrowse link
AV node cell to bundle of His cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
AV node cell-bundle of His cell adhesion involved in cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISO (MGI:3814765|PMID:18636119) BHF-UCL PMID:18636119 MGI:3814765 NCBI chr 2:75,027,499...75,078,206
Ensembl chr 2:75,001,562...75,078,033
JBrowse link
bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
bundle of His cell to Purkinje myocyte communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103224612 fucose-1-phosphate guanylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:58,618,409...58,941,264
Ensembl chr20:58,945,638...58,953,526
Ensembl chr20:58,945,638...58,953,526
JBrowse link
bundle of His cell to Purkinje myocyte communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G TBX5 T-box transcription factor 5 acts_upstream_of_positive_effect ISO (MGI:5449667|PMID:22728936) BHF-UCL PMID:22728936 MGI:5449667 NCBI chr11:109,638,694...109,696,619
Ensembl chr11:109,638,715...109,689,177
JBrowse link
bundle of His cell-Purkinje myocyte adhesion involved in cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNA3 catenin alpha 3 involved_in ISO (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr 9:63,669,561...65,406,737 JBrowse link
G DSC2 desmocollin 2 involved_in ISO (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:49,596,870...49,637,587
Ensembl chr18:49,599,940...49,639,526
JBrowse link
G DSG2 desmoglein 2 involved_in ISO (PMID:16505173) BHF-UCL PMID:16505173 NCBI chr18:49,174,539...49,227,519
Ensembl chr18:49,174,409...49,227,347
JBrowse link
G DSP desmoplakin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,611,243...64,656,297
Ensembl chr17:64,611,103...64,656,366
JBrowse link
G JUP junction plakoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322
JBrowse link
G PKP2 plakophilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:32,225,743...32,333,951
Ensembl chr11:32,225,600...32,333,615
JBrowse link
cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3664488|PMID:11046183) MGI
Ensembl
PMID:11046183 GO_REF:0000107 MGI:3664488
G SLC8A1 solute carrier family 8 member A1 involved_in ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr14:66,813,523...67,210,261 JBrowse link
cell communication involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:2445988|PMID:10747000) MGI PMID:10747000 MGI:2445988
G GJD3 gap junction protein delta 3 NOT|involved_in ISO (PMID:19168070) BHF-UCL PMID:19168070 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
cell-cell signaling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKP2 plakophilin 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr11:32,225,743...32,333,951
Ensembl chr11:32,225,600...32,333,615
JBrowse link
G TBX5 T-box transcription factor 5 acts_upstream_of_positive_effect ISO (MGI:5449667|PMID:22728936) BHF-UCL PMID:22728936 MGI:5449667 NCBI chr11:109,638,694...109,696,619
Ensembl chr11:109,638,715...109,689,177
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146
JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:66,449,154...66,937,643
Ensembl chr21:66,770,578...66,934,898
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146
JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146
JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3583874|PMID:12700358) Ensembl
MGI
PMID:12700358 GO_REF:0000107 MGI:3583874 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:5292192 NCBI chr23:17,595,661...17,735,675
Ensembl chr23:17,598,177...17,735,669
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
negative regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJD3 gap junction protein delta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
JBrowse link
negative regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJD3 gap junction protein delta 3 NOT|involved_in ISO
IEA
(PMID:19168070) BHF-UCL
Ensembl
PMID:19168070 GO_REF:0000107 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146
JBrowse link
positive regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TBX5 T-box transcription factor 5 acts_upstream_of ISO (MGI:5449667|PMID:22728936) BHF-UCL PMID:22728936 MGI:5449667 NCBI chr11:109,638,694...109,696,619
Ensembl chr11:109,638,715...109,689,177
JBrowse link
positive regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRDN triadin involved_in ISO (PMID:15731460) BHF-UCL PMID:15731460 NCBI chr13:50,145,787...50,580,397 JBrowse link
Purkinje myocyte to ventricular cardiac muscle cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
regulation of AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (MGI:2449848|PMID:12571597) BHF-UCL PMID:12571597 MGI:2449848 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISO (MGI:3814765|PMID:18636119) BHF-UCL PMID:18636119 MGI:3814765 NCBI chr 2:75,027,499...75,078,206
Ensembl chr 2:75,001,562...75,078,033
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
regulation of bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G RANGRF RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chr16:7,654,235...7,655,851
Ensembl chr16:7,654,439...7,655,703
JBrowse link
regulation of cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in ISO (PMID:12967627) BHF-UCL PMID:12967627 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785
JBrowse link
G AGT angiotensinogen involved_in ISO (PMID:17416596) BHF-UCL PMID:17416596 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324
JBrowse link
G EHD3 EH domain containing 3 involved_in ISO (MGI:5770033|PMID:25825486) UniProt PMID:25825486 MGI:5770033 NCBI chr14:76,237,345...76,271,557
Ensembl chr14:76,236,246...76,271,546
JBrowse link
G LOC103224612 fucose-1-phosphate guanylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:58,618,409...58,941,264
Ensembl chr20:58,945,638...58,953,526
Ensembl chr20:58,945,638...58,953,526
JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:75,391,833...75,399,003
Ensembl chr23:75,391,847...75,395,205
JBrowse link
G TMEM65 transmembrane protein 65 involved_in ISO (MGI:5699931|PMID:26403541) UniProt PMID:26403541 MGI:5699931 NCBI chr 8:118,883,409...118,944,834 JBrowse link
regulation of cell communication by electrical coupling involved in cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627
JBrowse link
G HRC histidine rich calcium binding protein involved_in ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chr 6:42,372,758...42,378,273
Ensembl chr 6:42,372,861...42,377,267
JBrowse link
G IRX3 iroquois homeobox 3 acts_upstream_of ISO (MGI:5288100|PMID:21825130) BHF-UCL PMID:21825130 MGI:5288100 NCBI chr 5:40,064,471...40,069,630
Ensembl chr 5:40,066,008...40,068,505
JBrowse link
G LOC103221883 uncharacterized LOC103221883 involved_in ISO (PMID:16213210)
(MGI:3690823|PMID:16213210)
BHF-UCL PMID:16213210 MGI:3690823 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027
JBrowse link
G LOC119618105 cAMP-specific 3',5'-cyclic phosphodiesterase 4D involved_in IEA Ensembl GO_REF:0000107
G SRI sorcin involved_in ISO (PMID:17130302) BHF-UCL PMID:17130302 NCBI chr21:60,730,164...60,751,054
Ensembl chr21:60,730,051...60,749,678
JBrowse link
regulation of heart rate by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:57,700,977...57,806,815 JBrowse link
G AKAP9 A-kinase anchoring protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:56,889,669...57,061,526
Ensembl chr21:56,890,183...57,061,232
JBrowse link
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:3,112,605...3,173,522
Ensembl chr10:3,113,868...3,173,620
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3583874|PMID:12700358) MGI
Ensembl
PMID:12700358 GO_REF:0000107 MGI:3583874 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:66,449,154...66,937,643
Ensembl chr21:66,770,578...66,934,898
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617
JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627
JBrowse link
G CTNNA3 catenin alpha 3 involved_in ISO (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr 9:63,669,561...65,406,737 JBrowse link
G DSC2 desmocollin 2 involved_in ISO (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:49,596,870...49,637,587
Ensembl chr18:49,599,940...49,639,526
JBrowse link
G DSG2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chr18:49,174,539...49,227,519
Ensembl chr18:49,174,409...49,227,347
JBrowse link
G DSP desmoplakin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,611,243...64,656,297
Ensembl chr17:64,611,103...64,656,366
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3664488|PMID:11046183) MGI PMID:11046183 MGI:3664488
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292
JBrowse link
G ISL1 ISL LIM homeobox 1 acts_upstream_of ISO (MGI:5688210|PMID:26193633) BHF-UCL PMID:26193633 MGI:5688210 NCBI chr 4:47,665,861...47,678,631
Ensembl chr 4:47,666,536...47,677,552
JBrowse link
G JUP junction plakoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6402838|PMID:32109384) MGI
Ensembl
PMID:32109384 GO_REF:0000107 MGI:6402838 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3615054|PMID:14561835) MGI
TreeGrafter
PMID:14561835 GO_REF:0000118 MGI:3615054 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:65,699,558...65,710,305
Ensembl chr 1:65,700,156...65,700,467
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr10:108,971,949...108,972,461 JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:97,477,667...97,485,376
Ensembl chr  X:97,478,562...97,478,987
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860395|PMID:10843886)
(PMID:7889573)
MGI
TreeGrafter
Ensembl
PMID:7889573 PMID:10843886 GO_REF:0000107 GO_REF:0000118 MGI:1860395 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794
JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:57,733,032...57,759,292
Ensembl chr16:57,735,861...57,758,421
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863
JBrowse link
G PKP2 plakophilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:32,225,743...32,333,951
Ensembl chr11:32,225,600...32,333,615
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr19:18,507,184...18,801,535 JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,538,694...109,552,745
Ensembl chr 1:109,538,652...109,552,740
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:115,031,634...115,057,829
Ensembl chr 1:115,034,508...115,057,787
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,507,121...109,528,512
Ensembl chr 1:109,509,979...109,528,721
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6402838|PMID:32109384)
(MGI:2179151|PMID:11972032), (MGI:3629469|PMID:15809371), (MGI:3695100|PMID:16172272), (MGI:4354492|PMID:15932895)
MGI
Ensembl
PMID:11972032 PMID:15809371 PMID:15932895 PMID:16172272 PMID:32109384 GO_REF:0000107 MGI:2179151 MGI:3629469 MGI:3695100 MGI:4354492 MGI:6402838 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146
JBrowse link
regulation of Purkinje myocyte action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
regulation of SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
G TBX18 T-box transcription factor 18 acts_upstream_of ISO (PMID:23242162) BHF-UCL PMID:23242162 NCBI chr13:9,407,384...9,441,157
Ensembl chr13:9,411,004...9,439,642
JBrowse link
regulation of the force of heart contraction by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLN phospholamban acts_upstream_of_or_within ISO (MGI:1352349|PMID:10644605) MGI PMID:10644605 MGI:1352349 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:105,613,289...105,670,868
Ensembl chr20:105,613,338...105,674,208
JBrowse link
SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (MGI:5430886|PMID:18832177) BHF-UCL PMID:18832177 MGI:5430886 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3664488|PMID:11046183) MGI PMID:11046183 MGI:3664488
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:115,031,634...115,057,829
Ensembl chr 1:115,034,508...115,057,787
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
SA node cell to atrial cardiac muscle cell communication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,487,776...61,174,351
Ensembl chr 7:60,938,523...61,175,519
JBrowse link
SA node cell to atrial cardiac muscle cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16771
    multicellular organismal process 7272
      system process 2173
        regulation of system process 652
          regulation of blood circulation 281
            regulation of heart contraction 209
              cardiac conduction 70
                cell communication involved in cardiac conduction + 43
                negative regulation of cardiac conduction 1
                positive regulation of cardiac conduction 1
                regulation of cardiac conduction + 12
                regulation of heart rate by cardiac conduction 39
                regulation of the force of heart contraction by cardiac conduction 2
Path 2
Term Annotations click to browse term
  biological_process 16771
    multicellular organismal process 7272
      system process 2173
        circulatory system process 570
          blood circulation 543
            heart contraction 249
              regulation of heart contraction 209
                cardiac conduction 70
                  cell communication involved in cardiac conduction + 43
                  negative regulation of cardiac conduction 1
                  positive regulation of cardiac conduction 1
                  regulation of cardiac conduction + 12
                  regulation of heart rate by cardiac conduction 39
                  regulation of the force of heart contraction by cardiac conduction 2
paths to the root