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ONTOLOGY REPORT - ANNOTATIONS

Term:mammary gland epithelium development
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Accession:GO:0061180 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms:exact_synonym: breast epithelium development

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mammary gland epithelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:5528587|PMID:23840669)		 Ensembl
RGD		 PMID:23840669 GO_REF:0000107 MGI:5528587 NCBI chr19:52,347,480...52,404,608
Ensembl chr19:52,347,580...52,404,607 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:97169 (MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:1355063 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO MGI:97168 (MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5528587|PMID:23840669)		 Ensembl
RGD		 PMID:23840669 GO_REF:0000107 MGI:5528587 NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570 		JBrowse link
G Prlr prolactin receptor acts_upstream_of_or_within ISO (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035|MGI:103036 (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057 		JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420 		JBrowse link
G Wnt3 Wnt family member 3 involved_in ISO
IEA		 (PMID:8168088)
GO_REF:0000107		 RGD
Ensembl		 PMID:8168088 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579 		JBrowse link
G Wnt7b Wnt family member 7B involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723 		JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034833.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr12:53,872...54,885 JBrowse link
G AABR07071701.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 8:126,975,833...126,976,850 JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:3054694 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2388024 (MGI:1932625|PMID:11283268)		 Ensembl
RGD		 PMID:11283268 GO_REF:0000107 MGI:1932625 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:5284750 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206 		JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (MGI:2667785|PMID:12871699), (MGI:3828920|PMID:18977342) RGD PMID:12871699 PMID:18977342 MGI:2667785 MGI:3828920 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357 		JBrowse link
G LOC102554748 nidogen-2-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:380,313...427,615
Ensembl chr 7:380,741...381,732 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3663738 (MGI:3692480|PMID:16973609)
PMID:21873635		 RGD PMID:16973609, PMID:21873635, PMID:21873635 MGI:3692480, RGD:13792537, RGD:13792537 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2156191 (MGI:3849913|PMID:19503830)
PMID:21873635		 RGD PMID:19503830, PMID:21873635, PMID:21873635 MGI:3849913, RGD:13792537, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)		 Ensembl
RGD		 PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:3839212|PMID:19261859) RGD PMID:19261859 MGI:3839212 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180693|PMID:8864124) RGD PMID:8864124 MGI:2180693 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1857247 (MGI:3589531|PMID:16007215) RGD PMID:16007215 MGI:3589531 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (MGI:3608166|PMID:16222716) RGD PMID:16222716 MGI:3608166 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526 		JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194 		JBrowse link
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1931655|PMID:11170346)		 UniProt
RGD		 PMID:11170346 GO_REF:0000024 MGI:1931655 NCBI chr 8:75,992,751...75,995,371
Ensembl chr 8:75,992,755...75,995,371 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:96432 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2386679 (MGI:2654263|PMID:12620994)		 Ensembl
RGD		 PMID:12620994 GO_REF:0000107 MGI:2654263 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2446740|PMID:12456807)		 UniProt
RGD		 PMID:12456807 GO_REF:0000024 MGI:2446740 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915 		JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:3629536|PMID:12021201)		 Ensembl
RGD		 PMID:12021201 GO_REF:0000107 MGI:3629536 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3761053|PMID:17898001)		 Ensembl
RGD		 PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)		 Ensembl
RGD		 PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3761053|PMID:17898001)		 Ensembl
RGD		 PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357 		JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within ISO MGI:2445230 (MGI:5614192|PMID:25049204) RGD PMID:25049204 MGI:5614192 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423 		JBrowse link
G Robo1 roundabout guidance receptor 1 acts_upstream_of_or_within ISO MGI:3043142 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261 		JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361 		JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 acts_upstream_of_or_within ISO MGI:5473214 (MGI:6369467|PMID:31604923) RGD PMID:31604923 MGI:6369467 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:1926565|PMID:10919287)		 Ensembl
RGD		 PMID:10919287 GO_REF:0000107 MGI:1926565 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Vdr vitamin D receptor acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2183404 (MGI:3051725|PMID:15178742)		 Ensembl
RGD		 PMID:15178742 GO_REF:0000107 MGI:3051725 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) RGD PMID:10331984 PMID:17369357 MGI:1336843 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO MGI:1931860 (MGI:1859522|PMID:11015591) RGD PMID:11015591 MGI:1859522 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within ISO MGI:3574361 (MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3761053|PMID:17898001)		 Ensembl
RGD		 PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (MGI:1203302|PMID:9477327) RGD PMID:9477327 MGI:1203302 NCBI chr 4:181,663,425...181,674,181 JBrowse link
mammary gland bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:5319554 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066 		JBrowse link
mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:2151643|PMID:11783999) RGD PMID:11783999 MGI:2151643 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:1298218 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1278315 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within ISO MGI:1857745 (MGI:3758540|PMID:12198239) RGD PMID:12198239 MGI:3758540 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Ntn1 netrin 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1315205 (MGI:3617129|PMID:16439476)		 Ensembl
RGD		 PMID:16439476 GO_REF:0000107 MGI:3617129 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:1346456 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (MGI:4359580|PMID:19041750) RGD PMID:19041750 MGI:4359580 NCBI chr 7:117,105,810...117,128,802
Ensembl chr 7:117,105,810...117,128,798 		JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:105088|MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361 		JBrowse link
mammary gland epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within ISO MGI:2149329 (MGI:1353872|PMID:10707954) RGD PMID:10707954 MGI:1353872 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 acts_upstream_of_or_within ISO MGI:97763 (MGI:3623843|PMID:16469767) RGD PMID:16469767 MGI:3623843 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3689173|PMID:16837552)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16837552 GO_REF:0000024 GO_REF:0000107 MGI:3689173 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:49188|PMID:1376141) RGD PMID:1376141 MGI:49188 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:3624927
G Irf6 interferon regulatory factor 6 acts_upstream_of_or_within ISO (PMID:18212048) RGD PMID:18212048 NCBI chr13:111,870,121...111,889,328
Ensembl chr13:111,870,121...111,889,328 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:28068668) RGD PMID:28068668 NCBI chr 1:1,784,078...1,817,310
Ensembl chr 1:1,784,078...1,817,310 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway involved_in ISO (MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:5634223 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase IEP RGD PMID:16086375 RGD:2316910 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190 		JBrowse link
G Prlr prolactin receptor acts_upstream_of_or_within ISO MGI:1335079 (MGI:3623843|PMID:16469767) RGD PMID:16469767 MGI:3623843 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:1346456 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873 		JBrowse link
G Smo smoothened, frizzled class receptor acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1934268|MGI:2445832 (MGI:3696007|PMID:17199044)		 Ensembl
RGD		 PMID:17199044 GO_REF:0000107 MGI:3696007 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521) RGD PMID:21337521 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028 		JBrowse link
mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:3054694 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837 		JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO MGI:99484 (MGI:3045614|PMID:11747812) RGD PMID:11747812 MGI:3045614 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within ISO MGI:2149329 (MGI:1353782|PMID:10683373) RGD PMID:10683373 MGI:1353782 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex acts_upstream_of_or_within ISO MGI:3045616|MGI:88313 (MGI:3045614|PMID:11747812) RGD PMID:11747812 MGI:3045614 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:5284750 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2446740|PMID:12456807)		 UniProt
RGD		 PMID:12456807 GO_REF:0000024 MGI:2446740 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276|MGI:4443002 (MGI:3578445|PMID:15843544), (MGI:4442276|PMID:20351249) RGD PMID:15843544 PMID:20351249 MGI:3578445 MGI:4442276 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:1888385 (MGI:5424261|PMID:22588720) RGD PMID:22588720 MGI:5424261 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within ISO MGI:1859962 (MGI:1889907|PMID:11051546) RGD PMID:11051546 MGI:1889907 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in IEA
ISO		 GO_REF:0000107
(PMID:15930293)		 Ensembl
RGD		 PMID:15930293 GO_REF:0000107 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of_or_within ISO MGI:1926877 (MGI:3047035|PMID:15105443) RGD PMID:15105443 MGI:3047035 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (MGI:3828920|PMID:18977342) RGD PMID:18977342 MGI:3828920 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19483726) RGD PMID:19483726 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within ISO MGI:3574361 (MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317 		JBrowse link
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within ISO MGI:4439325|MGI:88313 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422 		JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO MGI:3580016 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr 2:187,447,477...187,489,630
Ensembl chr 2:187,447,501...187,489,630 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357 		JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2445230 (MGI:5614192|PMID:25049204)
PMID:21873635		 RGD PMID:25049204, PMID:21873635, PMID:21873635 MGI:5614192, RGD:13792537, RGD:13792537 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423 		JBrowse link
G Rreb1 ras responsive element binding protein 1 involved_in ISO (PMID:18394891) RGD PMID:18394891 NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266 		JBrowse link
G Rtn4 reticulon 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27353365)		 Ensembl
RGD		 PMID:27353365 GO_REF:0000107 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)		 RGD PMID:21317240 PMID:21337521 MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028 		JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180558 (MGI:3830397|PMID:19164602) RGD PMID:19164602 MGI:3830397 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917 		JBrowse link
G Etv5 ETS variant transcription factor 5 acts_upstream_of_or_within ISO (MGI:2667785|PMID:12871699) RGD PMID:12871699 MGI:2667785 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within ISO MGI:3574361 (MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:98958 (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:96079|MGI:98725 (MGI:3761053|PMID:17898001)		 Ensembl
RGD		 PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1857429 (MGI:1337911|PMID:10363969)		 Ensembl
RGD		 PMID:10363969 GO_REF:0000107 MGI:1337911 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Deaf1 DEAF1 transcription factor involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3822223|PMID:18826651)
(PMID:18826651)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18826651 GO_REF:0000024 GO_REF:0000107 MGI:3822223 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA		 (PMID:16945136)
GO_REF:0000107		 RGD
Ensembl		 PMID:16945136 GO_REF:0000107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:3624927
G Pygo2 pygopus family PHD finger 2 acts_upstream_of_or_within ISO MGI:3711738 (MGI:4821247|PMID:19487454) RGD PMID:19487454 MGI:4821247 NCBI chr 2:188,757,167...188,762,285
Ensembl chr 2:188,757,489...188,762,282 		JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)		 Ensembl
RGD		 PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Pgr progesterone receptor acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1857933 (MGI:1354852|PMID:10733525)		 Ensembl
RGD		 PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1857453 (MGI:1354852|PMID:10733525)		 Ensembl
RGD		 PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        tissue development 2079
          epithelium development 1275
            mammary gland epithelium development 84
              mammary gland duct morphogenesis + 44
              mammary gland epithelial cell differentiation + 17
              mammary gland epithelial cell proliferation + 32
Path 2
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              gland development 665
                mammary gland development 208
                  mammary gland epithelium development 84
                    mammary gland duct morphogenesis + 44
                    mammary gland epithelial cell differentiation + 17
                    mammary gland epithelial cell proliferation + 32
paths to the root