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ONTOLOGY REPORT - ANNOTATIONS

Term:mammary gland epithelium development
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Accession:GO:0061180 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms:exact_synonym: breast epithelium development


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mammary gland epithelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5528587|PMID:23840669)		 Ensembl
RGD		 PMID:23840669 GO_REF:0000107 MGI:5528587 NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:97169 (MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:1355063 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO MGI:97168 (MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:1355063 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 acts_upstream_of_or_within ISO (MGI:5528587|PMID:23840669) RGD PMID:23840669 MGI:5528587 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405 		JBrowse link
G Prlr prolactin receptor acts_upstream_of_or_within ISO (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035|MGI:103036 (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402 		JBrowse link
G Wnt3 Wnt family member 3 involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt7b Wnt family member 7B involved_in ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 7:116,634,817...116,679,089
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:3054694 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2388024 (MGI:1932625|PMID:11283268)		 Ensembl
RGD		 PMID:11283268 GO_REF:0000107 MGI:1932625 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:5284750 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (MGI:2667785|PMID:12871699), (MGI:3828920|PMID:18977342) RGD PMID:12871699 PMID:18977342 MGI:2667785 MGI:3828920 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3663738 (MGI:3692480|PMID:16973609)		 RGD PMID:16973609 PMID:21873635 MGI:3692480, RGD:13792537 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)		 Ensembl
RGD		 PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:3839212|PMID:19261859) RGD PMID:19261859 MGI:3839212 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180693|PMID:8864124) RGD PMID:8864124 MGI:2180693 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1857247 (MGI:3589531|PMID:16007215) RGD PMID:16007215 MGI:3589531 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (MGI:3608166|PMID:16222716) RGD PMID:16222716 MGI:3608166 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995 		JBrowse link
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISO (MGI:1931655|PMID:11170346) RGD PMID:11170346 MGI:1931655 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:96432 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr19:49,153,729...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386679 (MGI:2654263|PMID:12620994)		 Ensembl
RGD		 PMID:12620994 GO_REF:0000107 MGI:2654263 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2446740|PMID:12456807)		 UniProt
RGD		 PMID:12456807 GO_REF:0000024 MGI:2446740 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Esr1 estrogen receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:3629536|PMID:12021201)		 Ensembl
RGD		 PMID:12021201 GO_REF:0000107 MGI:3629536 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)		 Ensembl
RGD		 PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within ISO MGI:2445230 (MGI:5614192|PMID:25049204) RGD PMID:25049204 MGI:5614192 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Robo1 roundabout guidance receptor 1 acts_upstream_of_or_within ISO MGI:3043142 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 acts_upstream_of_or_within ISO MGI:5473214 (MGI:6369467|PMID:31604923) RGD PMID:31604923 MGI:6369467 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Esr1 estrogen receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:1926565|PMID:10919287)		 Ensembl
RGD		 PMID:10919287 GO_REF:0000107 MGI:1926565 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Vdr vitamin D receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2183404 (MGI:3051725|PMID:15178742)		 Ensembl
RGD		 PMID:15178742 GO_REF:0000107 MGI:3051725 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) RGD PMID:10331984 PMID:17369357 MGI:1336843 MGI:3703920 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO MGI:1931860 (MGI:1859522|PMID:11015591) RGD PMID:11015591 MGI:1859522 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3574361 (MGI:3695669|PMID:17065319)
GO_REF:0000107		 RGD
Ensembl		 PMID:17065319 GO_REF:0000107 MGI:3695669 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (MGI:1203302|PMID:9477327) RGD PMID:9477327 MGI:1203302 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
mammary gland bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:5319554 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:2151643|PMID:11783999) RGD PMID:11783999 MGI:2151643 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:1298218 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1278315 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857745 (MGI:3758540|PMID:12198239)
GO_REF:0000107		 RGD
Ensembl		 PMID:12198239 GO_REF:0000107 MGI:3758540 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntn1 netrin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1315205 (MGI:3617129|PMID:16439476)		 Ensembl
RGD		 PMID:16439476 GO_REF:0000107 MGI:3617129 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:1346456 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (MGI:4359580|PMID:19041750) RGD PMID:19041750 MGI:4359580 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:105088|MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
mammary gland epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within ISO MGI:2149329 (MGI:1353872|PMID:10707954) RGD PMID:10707954 MGI:1353872 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 acts_upstream_of_or_within ISO MGI:97763 (MGI:3623843|PMID:16469767) RGD PMID:16469767 MGI:3623843 NCBI chr 3:89,808,836...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3689173|PMID:16837552)		 UniProt
RGD		 PMID:16837552 GO_REF:0000024 MGI:3689173 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:49188|PMID:1376141) RGD PMID:1376141 MGI:49188 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:3624927 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Irf6 interferon regulatory factor 6 acts_upstream_of_or_within ISO (PMID:18212048) RGD PMID:18212048 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:28068668) RGD PMID:28068668 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway involved_in ISO (MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:5634223 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase IEP RGD PMID:16086375 RGD:2316910 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Prlr prolactin receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1335079 (MGI:3623843|PMID:16469767)
GO_REF:0000107		 RGD
Ensembl		 PMID:16469767 GO_REF:0000107 MGI:3623843 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:1346456 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934268|MGI:2445832 (MGI:3696007|PMID:17199044)		 Ensembl
RGD		 PMID:17199044 GO_REF:0000107 MGI:3696007 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521) RGD PMID:21337521 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of ISO MGI:4439325|MGI:88313 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:3054694 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO MGI:99484 (MGI:3045614|PMID:11747812)
MGI:3580016 (MGI:4438668|PMID:20075866)		 RGD PMID:11747812 PMID:20075866 MGI:3045614 MGI:4438668 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of ISO MGI:1926877 (MGI:3047035|PMID:15105443) RGD PMID:15105443 MGI:3047035 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within ISO MGI:2149329 (MGI:1353782|PMID:10683373) RGD PMID:10683373 MGI:1353782 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex acts_upstream_of_or_within ISO MGI:3045616|MGI:88313 (MGI:3045614|PMID:11747812) RGD PMID:11747812 MGI:3045614 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:5284750 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2446740|PMID:12456807)		 UniProt
RGD		 PMID:12456807 GO_REF:0000024 MGI:2446740 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 acts_upstream_of ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276|MGI:4443002 (MGI:3578445|PMID:15843544), (MGI:4442276|PMID:20351249) RGD PMID:15843544 PMID:20351249 MGI:3578445 MGI:4442276 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:3574361 (MGI:3695669|PMID:17065319)
GO_REF:0000107		 RGD
Ensembl		 PMID:17065319 GO_REF:0000107 MGI:3695669 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:1888385 (MGI:5424261|PMID:22588720) RGD PMID:22588720 MGI:5424261 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1859962 (MGI:1889907|PMID:11051546)
GO_REF:0000107		 RGD
Ensembl		 PMID:11051546 GO_REF:0000107 MGI:1889907 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in ISO
IEA		 (PMID:15930293)
GO_REF:0000107		 RGD
Ensembl		 PMID:15930293 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of_or_within ISO MGI:1926877 (MGI:3047035|PMID:15105443) RGD PMID:15105443 MGI:3047035 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (MGI:3828920|PMID:18977342) RGD PMID:18977342 MGI:3828920 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19483726) RGD PMID:19483726 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3574361 (MGI:3695669|PMID:17065319)
GO_REF:0000107		 RGD
Ensembl		 PMID:17065319 GO_REF:0000107 MGI:3695669 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:18829537) RGD PMID:18829537 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within ISO MGI:4439325|MGI:88313 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO MGI:3580016 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within ISO MGI:2445230 (MGI:5614192|PMID:25049204) RGD PMID:25049204 MGI:5614192 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Rreb1 ras responsive element binding protein 1 involved_in ISO (PMID:18394891) RGD PMID:18394891 NCBI chr17:26,876,686...27,002,615
Ensembl chr17:26,876,697...27,002,615 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO
IEA		 (PMID:27353365)
GO_REF:0000107		 RGD
Ensembl		 PMID:27353365 GO_REF:0000107 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)		 RGD PMID:21317240 PMID:21337521 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180558 (MGI:3830397|PMID:19164602) RGD PMID:19164602 MGI:3830397 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Etv5 ETS variant transcription factor 5 acts_upstream_of_or_within ISO (MGI:2667785|PMID:12871699) RGD PMID:12871699 MGI:2667785 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3574361 (MGI:3695669|PMID:17065319)
GO_REF:0000107		 RGD
Ensembl		 PMID:17065319 GO_REF:0000107 MGI:3695669 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:98958 (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:96079|MGI:98725 (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:1337911|PMID:10363969) RGD PMID:10363969 MGI:1337911 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Deaf1 DEAF1 transcription factor involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3822223|PMID:18826651)
GO_REF:0000107
(PMID:18826651)		 UniProt
RGD
Ensembl		 PMID:18826651 GO_REF:0000024 GO_REF:0000107 MGI:3822223 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16945136)		 Ensembl
RGD		 PMID:16945136 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:3624927 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Pygo2 pygopus family PHD finger 2 acts_upstream_of_or_within ISO MGI:3711738 (MGI:4821247|PMID:19487454) RGD PMID:19487454 MGI:4821247 NCBI chr 2:174,849,670...174,854,758
Ensembl chr 2:174,849,936...174,854,758 		JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)		 Ensembl
RGD		 PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Pgr progesterone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857933 (MGI:1354852|PMID:10733525)		 Ensembl
RGD		 PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857453 (MGI:1354852|PMID:10733525)		 Ensembl
RGD		 PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        tissue development 2203
          epithelium development 1372
            mammary gland epithelium development 81
              mammary gland duct morphogenesis + 41
              mammary gland epithelial cell differentiation + 17
              mammary gland epithelial cell proliferation + 32
Path 2
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        animal organ development 3697
          gland development 669
            mammary gland development 205
              mammary gland epithelium development 81
                mammary gland duct morphogenesis + 41
                mammary gland epithelial cell differentiation + 17
                mammary gland epithelial cell proliferation + 32
paths to the root