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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA destabilization
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Accession:GO:0061157 term browser browse the term
Definition:Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.


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mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Celf1 CUGBP, Elav-like family member 1 involved_in IDA PMID:30508596 ARUK-UCL PMID:30508596 RGD:38501076 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like acts_upstream_of_or_within ISO (MGI:3828348|PMID:17452450) RGD PMID:17452450 MGI:3828348 NCBI chr14:13,410,501...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase involved_in ISO
IEA
ISS
(PMID:28002401), (PMID:30197295)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28002401 PMID:30197295 GO_REF:0000024 GO_REF:0000107 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:27157137) RGD PMID:27157137 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R IMP RGD PMID:15798208 RGD:9854643 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867
JBrowse link
G Mettl14 methyltransferase like 14 involved_in ISO (MGI:5559905|PMID:24394384), (MGI:5927282|PMID:28965759) RGD PMID:24394384 PMID:28965759 MGI:5559905 MGI:5927282 NCBI chr 2:211,530,598...211,546,858
Ensembl chr 2:211,530,602...211,546,821
JBrowse link
G Mettl16 methyltransferase like 16 involved_in ISO (MGI:6114846|PMID:29262316) RGD PMID:29262316 MGI:6114846 NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061
JBrowse link
G Mettl3 methyltransferase-like 3 involved_in ISO (MGI:5559905|PMID:24394384), (MGI:5621227|PMID:25569111), (MGI:5621254|PMID:25456834), (MGI:5927282|PMID:28965759), (MGI:6094929|PMID:28792938), (MGI:6095345|PMID:28637692) RGD PMID:24394384 PMID:25456834 PMID:25569111 PMID:28637692 PMID:28792938 More... MGI:5559905 MGI:5621227 MGI:5621254 MGI:5927282 MGI:6094929 MGI:6095345 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041
JBrowse link
G Pum1 pumilio RNA-binding family member 1 involved_in ISO (MGI:5640888|PMID:25768905) RGD PMID:25768905 MGI:5640888 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in ISO (PMID:29104163) RGD PMID:29104163 NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102
JBrowse link
G Rida reactive intermediate imine deaminase A homolog involved_in ISO
ISS
(PMID:30930054)
GO_REF:0000024
RGD
UniProt
PMID:30930054 GO_REF:0000024 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:6271078|PMID:29353861)
Ensembl
RGD
PMID:29353861 GO_REF:0000107 MGI:6271078 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) RGD PMID:29353861 MGI:6271078 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Ythdf1 YTH N(6)-methyladenosine RNA binding protein 1 involved_in ISO
IBA
(PMID:32492408)
PMID:21873635
(MGI:6490006|PMID:32943573)
RGD PMID:32492408 PMID:32943573 PMID:21873635 MGI:6490006, RGD:13792537 NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 involved_in ISO
IBA
(PMID:27558897), (PMID:28106072), (PMID:30559377), (PMID:30930054), (PMID:32169943), (PMID:32492408)
PMID:21873635
(MGI:6316439|PMID:29855337), (MGI:6316688|PMID:30065315), (MGI:6317061|PMID:30150673), (MGI:6490006|PMID:32943573), (MGI:6508516|PMID:31959747)
RGD PMID:27558897 PMID:28106072 PMID:29855337 PMID:30065315 PMID:30150673 More... MGI:6316439 MGI:6316688 MGI:6317061 MGI:6490006 MGI:6508516, RGD:13792537 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144
JBrowse link
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 involved_in ISO
IBA
(PMID:28106072), (PMID:32492408)
PMID:21873635
(MGI:6490006|PMID:32943573)
RGD PMID:28106072 PMID:32492408 PMID:32943573 PMID:21873635 MGI:6490006, RGD:13792537 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606
JBrowse link
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) RGD PMID:21336257 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO
ISS
(PMID:26489465)
GO_REF:0000024
RGD
UniProt
PMID:26489465 GO_REF:0000024 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in ISO (PMID:28297718) RGD PMID:28297718 NCBI chr18:28,378,692...28,381,316
Ensembl chr18:28,378,692...28,381,316
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IMP RGD PMID:20805360 RGD:10042974 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO
ISS
(PMID:16126846), (PMID:28275056)
GO_REF:0000024
RGD
UniProt
PMID:16126846 PMID:28275056 GO_REF:0000024 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase involved_in ISO (PMID:24726324) RGD PMID:24726324 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
JBrowse link
G Plekhn1 pleckstrin homology domain containing N1 involved_in IBA
ISO
PMID:21873635
(MGI:6105829|PMID:27616329)
(PMID:29180010)
RGD PMID:27616329 PMID:29180010 PMID:21873635 MGI:6105829, RGD:13792537 NCBI chr 5:166,805,309...166,813,339
Ensembl chr 5:166,804,837...166,813,155
JBrowse link
G Qk quaking acts_upstream_of_or_within ISO (MGI:5316962|PMID:20631256) RGD PMID:20631256 MGI:5316962 NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in ISO (PMID:24375645) RGD PMID:24375645 NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5706859|PMID:26000482), (MGI:5751631|PMID:26255671) RGD PMID:26000482 PMID:26255671 MGI:5706859 MGI:5751631 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Tardbp TAR DNA binding protein involved_in ISO (PMID:28335005) RGD PMID:28335005 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Trim71 tripartite motif containing 71 involved_in ISO (PMID:23125361) RGD PMID:23125361 NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807
JBrowse link
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:24726324), (PMID:26255671) RGD PMID:24726324 PMID:26255671 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3842851|PMID:19322177), (MGI:5706859|PMID:26000482), (MGI:5706909|PMID:23185455), (MGI:5707103|PMID:26134560), (MGI:5751631|PMID:26255671)
PMID:21873635
(PMID:19909337)
UniProt
RGD
PMID:19322177 PMID:19909337 PMID:23185455 PMID:26000482 PMID:26134560 More... GO_REF:0000024 MGI:3842851 MGI:5706859 MGI:5706909 MGI:5707103 MGI:5751631, RGD:13792537 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D involved_in ISO (MGI:5707103|PMID:26134560) RGD PMID:26134560 MGI:5707103 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5784976|PMID:22701344), (MGI:5788345|PMID:27193233), (MGI:5795824|PMID:17288565)
(PMID:11719186), (PMID:14679154), (PMID:15187101), (PMID:15634918), (PMID:15687258), (PMID:15766526), (PMID:20221403), (PMID:27193233), (PMID:9703499)
UniProt
Ensembl
RGD
PMID:9703499 PMID:11719186 PMID:14679154 PMID:15187101 PMID:15634918 More... GO_REF:0000024 GO_REF:0000107 MGI:5784976 MGI:5788345 MGI:5795824 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4818820|PMID:20622884), (MGI:5779430|PMID:27102483), (MGI:5784967|PMID:24733888), (MGI:5784968|PMID:24700863), (MGI:5784976|PMID:22701344)
(PMID:12198173), (PMID:15467755), (PMID:15538381), (PMID:15687258), (PMID:18326031), (PMID:19179481), (PMID:24700863), (PMID:25014217), (PMID:25106868), (PMID:26542173)
UniProt
RGD
PMID:12198173 PMID:15467755 PMID:15538381 PMID:15687258 PMID:18326031 More... GO_REF:0000024 MGI:4818820 MGI:5779430 MGI:5784967 MGI:5784968 MGI:5784976 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (PMID:25106868)
(MGI:4818820|PMID:20622884), (MGI:5784976|PMID:22701344)
RGD PMID:20622884 PMID:22701344 PMID:25106868 MGI:4818820 MGI:5784976 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07066144.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Cnot7 CCR4-NOT transcription complex, subunit 7 acts_upstream_of_or_within ISO MGI:109382 (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Dcp1a decapping mRNA 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:5,656,788...5,702,151
Ensembl chr16:5,656,773...5,702,140
JBrowse link
G Dcp1b decapping mRNA 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145
JBrowse link
G Dcp2 decapping mRNA 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Dcps decapping enzyme, scavenger involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:33,468,669...33,524,407 JBrowse link
G LOC103690064 m7GpppN-mRNA hydrolase-like involved_in IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537
G Lsm1 LSM1 homolog, mRNA degradation associated involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:66,277,345...66,288,852
Ensembl chr16:66,277,345...66,288,852
JBrowse link
G Noct nocturnin acts_upstream_of_or_within ISO MGI:1298230 (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Pan3 poly(A) specific ribonuclease subunit PAN3 acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr12:7,476,707...7,595,380
Ensembl chr12:7,476,697...7,599,204
JBrowse link
G Patl1 PAT1 homolog 1, processing body mRNA decay factor involved_in ISO
IBA
ISS
(PMID:20584987), (PMID:20852261)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20584987 PMID:20852261 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:208,831,115...208,862,904
Ensembl chr 1:208,831,115...208,862,857
JBrowse link
G Patl2 PAT1 homolog 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:109,072,958...109,087,425
Ensembl chr 3:109,075,290...109,083,253
JBrowse link
exonucleolytic catabolism of deadenylated mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot6 CCR4-NOT transcription complex, subunit 6 involved_in ISO
IEA
ISS
(PMID:20065043)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20065043 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO
IBA
(PMID:20065043), (PMID:21336257)
PMID:21873635
RGD PMID:20065043 PMID:21336257 PMID:21873635 RGD:13792537 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Cnot8 CCR4-NOT transcription complex, subunit 8 involved_in ISO
IBA
(PMID:20065043)
PMID:21873635
RGD PMID:20065043 PMID:21873635 RGD:13792537 NCBI chr10:42,281,614...42,294,740
Ensembl chr10:42,281,722...42,294,730
JBrowse link
G Exosc2 exosome component 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
JBrowse link
G Exosc3 exosome component 3 involved_in ISO
IBA
(PMID:11782436)
PMID:21873635
RGD PMID:11782436 PMID:21873635 RGD:13792537 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc5 exosome component 5 involved_in ISO (PMID:11782436) RGD PMID:11782436 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Exosc7 exosome component 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Exosc8 exosome component 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exosc9 exosome component 9 involved_in ISO
IBA
(PMID:11782436)
PMID:21873635
RGD PMID:11782436 PMID:21873635 RGD:13792537 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:32354837) RGD PMID:32354837 NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793
JBrowse link
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent4a terminal nucleotidyltransferase 4A involved_in ISO (PMID:30026317) RGD PMID:30026317 NCBI chr 1:33,766,121...33,799,433
Ensembl chr 1:33,765,672...33,799,433
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) RGD PMID:30026317 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in ISO
IEA
ISS
(PMID:18377426)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18377426 GO_REF:0000024 GO_REF:0000107 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
nuclear polyadenylation-dependent mRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc7 exosome component 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Exosc8 exosome component 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exosc9 exosome component 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:16934922) RGD PMID:16934922 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696
JBrowse link
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot1 CCR4-NOT transcription complex, subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like acts_upstream_of_or_within ISO (MGI:3828348|PMID:17452450) RGD PMID:17452450 MGI:3828348 NCBI chr14:13,410,501...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Pde12 phosphodiesterase 12 involved_in ISO
IEA
IBA
(PMID:21245038)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:21245038 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr16:1,915,386...1,925,427
Ensembl chr16:1,915,386...1,925,887
JBrowse link
G Polr2d RNA polymerase II subunit D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:23,418,097...23,425,228
Ensembl chr18:23,418,097...23,425,228
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5706859|PMID:26000482), (MGI:5751631|PMID:26255671) RGD PMID:26000482 PMID:26255671 MGI:5706859 MGI:5751631 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
G Zfp36 zinc finger protein 36 involved_in
acts_upstream_of_or_within
ISO (PMID:23644599)
(MGI:3589099|PMID:15814898)
RGD PMID:15814898 PMID:23644599 MGI:3589099 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 acts_upstream_of_or_within ISO (MGI:3589099|PMID:15814898) RGD PMID:15814898 MGI:3589099 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 acts_upstream_of_or_within ISO (MGI:3589099|PMID:15814898) RGD PMID:15814898 MGI:3589099 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot2 CCR4-NOT transcription complex, subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:52,130,444...52,222,338
Ensembl chr 7:52,130,441...52,223,575
JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167
JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 involved_in IBA
IEA
ISS
ISO
PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:20595389)
Ensembl
UniProt
RGD
PMID:20595389 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:13,410,501...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857946 (MGI:1934053|PMID:11337385)
Ensembl
RGD
PMID:11337385 GO_REF:0000107 MGI:1934053 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Pan2 poly(A) specific ribonuclease subunit PAN2 involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 7:729,146...747,744
Ensembl chr 7:729,562...747,744
JBrowse link
G Pan3 poly(A) specific ribonuclease subunit PAN3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:7,476,707...7,595,380
Ensembl chr12:7,476,697...7,599,204
JBrowse link
G Parn poly(A)-specific ribonuclease involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3785219|PMID:18337750)
RGD PMID:18337750 PMID:21873635 MGI:3785219, RGD:13792537 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560
JBrowse link
G Pnldc1 PARN like ribonuclease domain containing exonuclease 1 involved_in IBA
ISO
PMID:21873635
(MGI:5825409|PMID:27515512)
(PMID:27515512)
RGD PMID:27515512 PMID:21873635 MGI:5825409, RGD:13792537 NCBI chr 1:47,843,224...47,861,675
Ensembl chr 1:47,843,224...47,861,674
JBrowse link
G Samd4a sterile alpha motif domain containing 4A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
JBrowse link
G Samd4b sterile alpha motif domain containing 4B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,689,413...83,728,652
Ensembl chr 1:83,689,413...83,713,853
JBrowse link
G Zfp36 zinc finger protein 36 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3589099|PMID:15814898)
(PMID:23644599)
Ensembl
RGD
PMID:15814898 PMID:23644599 GO_REF:0000107 MGI:3589099 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
polyuridylation-dependent mRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
JBrowse link
G Tut4 terminal uridylyl transferase 4 involved_in ISO (MGI:6162305|PMID:28792939) RGD PMID:28792939 MGI:6162305 NCBI chr 5:123,201,723...123,306,582
Ensembl chr 5:123,203,003...123,306,465
JBrowse link
G Tut7 terminal uridylyl transferase 7 involved_in ISO (MGI:6162305|PMID:28792939) RGD PMID:28792939 MGI:6162305 NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169
JBrowse link
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5486537|PMID:19716330)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19716330 GO_REF:0000024 GO_REF:0000107 MGI:5486537 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 involved_in ISO (PMID:21278420) RGD PMID:21278420 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:21278420)
(MGI:5486537|PMID:19716330)
RGD PMID:19716330 PMID:21278420 MGI:5486537 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) RGD PMID:21336257 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:14731398) RGD PMID:14731398 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 involved_in ISO (PMID:24736845) RGD PMID:24736845 NCBI chr 1:259,897,659...259,901,501
Ensembl chr 1:259,897,939...259,898,730
JBrowse link
G Nanos2 nanos C2HC-type zinc finger 2 involved_in ISO (PMID:24736845) RGD PMID:24736845 NCBI chr 1:78,635,668...78,637,128
Ensembl chr 1:78,635,668...78,637,128
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 involved_in ISO (PMID:24736845) RGD PMID:24736845 NCBI chr19:23,978,465...23,988,933
Ensembl chr19:23,985,504...23,988,932
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5486537|PMID:19716330)
UniProt
RGD
PMID:19716330 GO_REF:0000024 MGI:5486537 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B involved_in ISO (PMID:19716330) RGD PMID:19716330 NCBI chr 7:112,252,351...112,469,829
Ensembl chr 7:112,252,359...112,461,790
JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C involved_in ISO (PMID:21984185) RGD PMID:21984185 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21336257)
UniProt
Ensembl
RGD
PMID:21336257 GO_REF:0000024 GO_REF:0000107 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5487524|PMID:21278420)
(PMID:12748283)
UniProt
Ensembl
RGD
PMID:12748283 PMID:21278420 GO_REF:0000024 GO_REF:0000107 MGI:5487524 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in IDA PMID:12748283 UniProt PMID:12748283 RGD:11344945 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (MGI:5320815|PMID:22367205) RGD PMID:22367205 MGI:5320815 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5486537|PMID:19716330)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19716330 GO_REF:0000024 GO_REF:0000107 MGI:5486537 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Btg2 BTG anti-proliferation factor 2 acts_upstream_of_or_within ISO (PMID:18337750) RGD PMID:18337750 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 involved_in ISO (PMID:21278420), (PMID:23644599) RGD PMID:21278420 PMID:23644599 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:21278420)
(MGI:5486537|PMID:19716330)
RGD PMID:19716330 PMID:21278420 MGI:5486537 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) RGD PMID:21336257 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:32354837) RGD PMID:32354837 NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5486537|PMID:19716330)
UniProt
RGD
PMID:19716330 GO_REF:0000024 MGI:5486537 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744
JBrowse link
G Polr2g RNA polymerase II subunit G involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686
JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B involved_in ISO
IBA
(PMID:19716330)
PMID:21873635
RGD PMID:19716330 PMID:21873635 RGD:13792537 NCBI chr 7:112,252,351...112,469,829
Ensembl chr 7:112,252,359...112,461,790
JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C involved_in ISO
IBA
(PMID:21984185)
PMID:21873635
RGD PMID:21984185 PMID:21873635 RGD:13792537 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in ISO
IEA
ISS
(PMID:21336257)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21336257 GO_REF:0000024 GO_REF:0000107 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5487524|PMID:21278420), (MGI:5795819|PMID:20595389)
(PMID:10330172)
UniProt
Ensembl
RGD
PMID:10330172 PMID:20595389 PMID:21278420 GO_REF:0000024 GO_REF:0000107 MGI:5487524 MGI:5795819 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:31636267) RGD PMID:31636267 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological quality 4181
        regulation of RNA stability 168
          regulation of mRNA stability 155
            mRNA destabilization 83
              3'-UTR-mediated mRNA destabilization 18
              deadenylation involved in gene silencing by miRNA 0
              nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 53
              polyadenylation-dependent mRNA catabolic process + 4
              polyuridylation-dependent mRNA catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10721
        cellular aromatic compound metabolic process 5598
          nucleobase-containing compound metabolic process 5380
            nucleic acid metabolic process 4890
              RNA metabolic process 4360
                regulation of RNA metabolic process 3527
                  positive regulation of RNA metabolic process 1783
                    positive regulation of mRNA metabolic process 124
                      positive regulation of mRNA catabolic process 86
                        mRNA destabilization 83
                          3'-UTR-mediated mRNA destabilization 18
                          deadenylation involved in gene silencing by miRNA 0
                          nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 53
                          polyadenylation-dependent mRNA catabolic process + 4
                          polyuridylation-dependent mRNA catabolic process + 3
paths to the root