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ONTOLOGY REPORT - ANNOTATIONS

Term:endothelial tube morphogenesis
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Accession:GO:0061154 term browser browse the term
Definition:The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


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endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691 		JBrowse link
G BSG basigin (Ok blood group) involved_in ISO (PMID:19837976) UniProt PMID:19837976 Ensembl chr19:539,815...551,456 JBrowse link
G CCM2 CCM2 scaffold protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19151727) MGI
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr 7:45,714,413...45,791,016
Ensembl chr 7:45,808,145...45,858,828 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in ISO (PMID:19592636) BHF-UCL PMID:19592636 NCBI chr 6:31,327,250...31,331,250 JBrowse link
G CTNNB1 catenin beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO RGD PMID:24955809 RGD:11352686 NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647 		JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:25942475 RGD:126925211 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109 		JBrowse link
G RHOB ras homolog family member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:20,433,576...20,435,986
Ensembl chr2A:20,549,254...20,549,844 		JBrowse link
blood vessel lumenization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL4 delta like canonical Notch ligand 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3056004|PMID:15466160) BHF-UCL PMID:15466160 MGI:3056004 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
endothelial tube lumen extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOA ras homolog family member A acts_upstream_of_or_within ISO (PMID:20208559) MGI PMID:20208559 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G STARD13 StAR related lipid transfer domain containing 13 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20208559) MGI
Ensembl		 PMID:20208559 GO_REF:0000107 NCBI chr13:14,359,252...14,607,742
Ensembl chr13:32,789,587...33,038,606 		JBrowse link
positive regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:10733500 RGD:2313864 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G ITGAD integrin subunit alpha D involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,539,562...23,572,705
Ensembl chr16:31,724,113...31,797,249 		JBrowse link
G ITGAX integrin subunit alpha X involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,574,807...23,612,638
Ensembl chr16:31,724,113...31,797,249 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798 		JBrowse link
regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,442,053...76,818,726
Ensembl chr 5:81,827,560...82,199,840 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001 		JBrowse link
G FOXP1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    developmental process 6563
      anatomical structure morphogenesis 2851
        tube morphogenesis 937
          epithelial tube morphogenesis 402
            endothelial tube morphogenesis 20
              blood vessel lumenization + 2
              endothelial tube formation 0
              endothelial tube lumen extension + 2
              negative regulation of endothelial tube morphogenesis 0
              positive regulation of endothelial tube morphogenesis 4
              pulmonary artery endothelial tube morphogenesis 0
              regulation of endothelial tube morphogenesis + 8
Path 2
Term Annotations click to browse term
  biological_process 16440
    developmental process 6563
      anatomical structure development 6172
        anatomical structure morphogenesis 2851
          tissue morphogenesis 701
            morphogenesis of an epithelium 590
              epithelial tube morphogenesis 402
                endothelial tube morphogenesis 20
                  blood vessel lumenization + 2
                  endothelial tube formation 0
                  endothelial tube lumen extension + 2
                  negative regulation of endothelial tube morphogenesis 0
                  positive regulation of endothelial tube morphogenesis 4
                  pulmonary artery endothelial tube morphogenesis 0
                  regulation of endothelial tube morphogenesis + 8
paths to the root