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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:lung secretory cell differentiation
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Accession:GO:0061140 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.


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lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5429471|PMID:22675208) MGI
Ensembl
PMID:22675208 GO_REF:0000107 MGI:5429471 NCBI chrNW_004936546:3,316,622...3,328,317
Ensembl chrNW_004936546:3,315,543...3,328,369
JBrowse link
G Hoxa5 homeobox A5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3665532|PMID:17003488) MGI
Ensembl
PMID:17003488 GO_REF:0000107 MGI:3665532 NCBI chrNW_004936478:3,768,757...3,771,850
Ensembl chrNW_004936478:3,769,258...3,771,840
JBrowse link
G Spdef SAM pointed domain containing ETS transcription factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709719|PMID:17347682) MGI
Ensembl
PMID:17347682 GO_REF:0000107 MGI:3709719 NCBI chrNW_004936476:24,563,591...24,571,739
Ensembl chrNW_004936476:24,563,591...24,570,692
JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3664178|PMID:9126746) MGI
Ensembl
PMID:9126746 GO_REF:0000107 MGI:3664178 NCBI chrNW_004936492:11,315,929...11,317,166
Ensembl chrNW_004936492:11,316,417...11,317,166
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (MGI:5429471|PMID:22675208) MGI PMID:22675208 MGI:5429471 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within ISO (MGI:2665161|PMID:12819782) MGI PMID:12819782 MGI:2665161 NCBI chrNW_004936750:430,780...439,247 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3577664|PMID:15531758) MGI
Ensembl
PMID:15531758 GO_REF:0000107 MGI:3577664 NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898
JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (MGI:5298325|PMID:21704616) MGI PMID:21704616 MGI:5298325 NCBI chrNW_004936593:311,245...638,625
Ensembl chrNW_004936593:311,245...566,800
JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695537|PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 MGI:3695537 NCBI chrNW_004936550:1,814,336...1,844,399
Ensembl chrNW_004936550:1,814,336...1,844,399
JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:3640953|PMID:16691571) MGI PMID:16691571 MGI:3640953 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
JBrowse link
G Nfib nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695537|PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 MGI:3695537 NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566
JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6501918|PMID:32484881) MGI
Ensembl
PMID:32484881 GO_REF:0000107 MGI:6501918 NCBI chrNW_004936485:1,787,048...1,796,233
Ensembl chrNW_004936485:1,787,028...1,798,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15101
    cellular process 14142
      cellular developmental process 3989
        cell differentiation 3988
          lung cell differentiation 40
            lung epithelial cell differentiation 40
              lung secretory cell differentiation 14
                lung goblet cell differentiation + 5
                lung neuroendocrine cell differentiation 1
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 15101
    developmental process 6018
      anatomical structure development 5681
        multicellular organism development 4643
          system development 4015
            respiratory system development 298
              lung development 262
                lung epithelium development 60
                  lung epithelial cell differentiation 40
                    lung secretory cell differentiation 14
                      lung goblet cell differentiation + 5
                      lung neuroendocrine cell differentiation 1
                      type II pneumocyte differentiation 8
paths to the root