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ONTOLOGY REPORT - ANNOTATIONS

Term:lung secretory cell differentiation
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Accession:GO:0061140 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.

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lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624754:17,402,788...17,445,469
Ensembl chrNW_004624754:17,404,125...17,428,736 		JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624739:13,428,049...13,440,949
Ensembl chrNW_004624739:13,428,130...13,442,070 		JBrowse link
G Cmtm6 CKLF like MARVEL transmembrane domain containing 6 acts_upstream_of_or_within ISO (PMID:38165704) MGI PMID:38165704 NCBI chrNW_004624788:10,547,530...10,575,610 JBrowse link
G Hoxa5 homeobox A5 acts_upstream_of_or_within ISO (PMID:17003488) MGI PMID:17003488 NCBI chrNW_004624739:3,461,779...3,464,543
Ensembl chrNW_004624739:3,461,800...3,464,785 		JBrowse link
G Spdef SAM pointed domain containing ETS transcription factor acts_upstream_of_or_within ISO (PMID:17347682) MGI PMID:17347682 NCBI chrNW_004624754:22,714,181...22,721,113
Ensembl chrNW_004624754:22,714,432...22,720,504 		JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:9126746) MGI PMID:9126746 NCBI chrNW_004624750:5,487,046...5,489,399
Ensembl chrNW_004624750:5,487,053...5,493,339 		JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624754:17,402,788...17,445,469
Ensembl chrNW_004624754:17,404,125...17,428,736 		JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004624754:17,402,788...17,445,469
Ensembl chrNW_004624754:17,404,125...17,428,736 		JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within ISO (PMID:12819782) MGI PMID:12819782 NCBI chrNW_004624740:31,305,629...31,315,103
Ensembl chrNW_004624740:31,303,006...31,315,101 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624759:10,904,626...10,983,509
Ensembl chrNW_004624759:10,904,989...10,983,574 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chrNW_004624730:50,111,873...50,447,035
Ensembl chrNW_004624730:50,111,346...50,450,164 		JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424 NCBI chrNW_004624770:9,772,818...9,799,837
Ensembl chrNW_004624770:9,772,818...9,798,259 		JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Nfib nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chrNW_004624736:18,372,418...18,586,390
Ensembl chrNW_004624736:18,377,624...18,586,424 		JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424 NCBI chrNW_004624838:300,902...304,944
Ensembl chrNW_004624838:300,458...305,517 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within ISO (PMID:32484881) MGI PMID:32484881 NCBI chrNW_004624741:19,214,436...19,222,511
Ensembl chrNW_004624741:19,214,536...19,222,530 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17808
    cellular process 17314
      cellular developmental process 4440
        cell differentiation 4439
          lung cell differentiation 35
            lung epithelial cell differentiation 35
              lung secretory cell differentiation 15
                lung goblet cell differentiation + 6
                lung neuroendocrine cell differentiation 1
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 17808
    developmental process 6555
      anatomical structure development 6100
        multicellular organism development 4897
          system development 4288
            respiratory system development 299
              lung development 262
                lung epithelium development 55
                  lung epithelial cell differentiation 35
                    lung secretory cell differentiation 15
                      lung goblet cell differentiation + 6
                      lung neuroendocrine cell differentiation 1
                      type II pneumocyte differentiation 8
paths to the root