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ONTOLOGY REPORT - ANNOTATIONS

Term:lung secretory cell differentiation
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Accession:GO:0061140 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.

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lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849 		JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:41,311,250...41,324,806
Ensembl chr21:41,312,415...41,326,663 		JBrowse link
G CMTM6 CKLF like MARVEL transmembrane domain containing 6 acts_upstream_of_or_within ISO (PMID:38165704) MGI PMID:38165704 NCBI chr15:76,980,942...77,005,174
Ensembl chr15:76,973,475...77,005,095 		JBrowse link
G HOXA5 homeobox A5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:31,224,017...31,227,819
Ensembl chr21:31,224,977...31,227,994 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:37,555,797...37,562,522
Ensembl chr17:37,555,820...37,562,036 		JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849 		JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849 		JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr28:15,210,016...15,224,874
Ensembl chr28:15,209,983...15,226,265 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432 		JBrowse link
G FNDC3B fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chr15:17,060,117...17,428,340
Ensembl chr15:17,059,959...17,428,339 		JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:58,312,328...58,345,472
Ensembl chr18:58,311,482...58,343,746 		JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G NFIB nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485 		JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056 		JBrowse link
G RBBP9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:47,549,090...47,559,459
Ensembl chr 2:47,552,024...47,559,365 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19940
    cellular process 19399
      cellular developmental process 4746
        cell differentiation 4745
          lung cell differentiation 37
            lung epithelial cell differentiation 37
              lung secretory cell differentiation 15
                lung goblet cell differentiation + 6
                lung neuroendocrine cell differentiation 1
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 19940
    developmental process 7014
      anatomical structure development 6563
        multicellular organism development 5257
          system development 4566
            respiratory system development 320
              lung development 279
                lung epithelium development 57
                  lung epithelial cell differentiation 37
                    lung secretory cell differentiation 15
                      lung goblet cell differentiation + 6
                      lung neuroendocrine cell differentiation 1
                      type II pneumocyte differentiation 8
paths to the root