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ONTOLOGY REPORT - ANNOTATIONS

Term:lung secretory cell differentiation
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Accession:GO:0061140 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.


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lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205 		JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879 		JBrowse link
G CMTM6 CKLF like MARVEL transmembrane domain containing 6 acts_upstream_of_or_within ISO (PMID:38165704) MGI PMID:38165704 NCBI chr 3:32,399,143...32,420,753
Ensembl chr 3:32,713,639...32,735,745 		JBrowse link
G HOXA5 homeobox A5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:27,786,040...27,789,339
Ensembl chr 7:27,385,175...27,388,990 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr 6:35,202,983...35,209,639 JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205 		JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205 		JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:7,418,406...7,433,020
Ensembl chr 7:6,203,329...6,221,202 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G FNDC3B fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chr 3:169,047,205...169,408,664
Ensembl chr 3:177,301,873...177,590,367 		JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424 NCBI chr18:15,411,764...15,444,402 JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G NFIB nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424
G RBBP9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:18,451,015...18,459,231
Ensembl chr20:18,422,652...18,430,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19472
    cellular process 18975
      cellular developmental process 4621
        cell differentiation 4620
          lung cell differentiation 35
            lung epithelial cell differentiation 35
              lung secretory cell differentiation 15
                lung goblet cell differentiation + 6
                lung neuroendocrine cell differentiation 1
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 19472
    developmental process 6808
      anatomical structure development 6362
        multicellular organism development 5090
          system development 4430
            respiratory system development 310
              lung development 274
                lung epithelium development 55
                  lung epithelial cell differentiation 35
                    lung secretory cell differentiation 15
                      lung goblet cell differentiation + 6
                      lung neuroendocrine cell differentiation 1
                      type II pneumocyte differentiation 8
paths to the root