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ONTOLOGY REPORT - ANNOTATIONS

Term:lung secretory cell differentiation
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Accession:GO:0061140 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.


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lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:1921373 (PMID:22675208) RGD PMID:22675208 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO MGI:1914004 (PMID:22675208) RGD PMID:22675208 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879 		JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member acts_upstream_of_or_within ISO (PMID:22675208) RGD PMID:22675208 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (PMID:17003488) RGD PMID:17003488 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Spdef SAM pointed domain containing ets transcription factor acts_upstream_of_or_within ISO (PMID:17347682) RGD PMID:17347682 NCBI chr20:5,771,440...5,785,893
Ensembl chr20:5,771,441...5,785,893 		JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (PMID:9126746) RGD PMID:9126746 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:1921373 (PMID:22675208) RGD PMID:22675208 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO MGI:1914004 (PMID:22675208) RGD PMID:22675208 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879 		JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:1344405|MGI:1921373 (PMID:22675208) RGD PMID:22675208 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO MGI:1344405|MGI:1914004 (PMID:22675208) RGD PMID:22675208 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879 		JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3497919 (PMID:12819782)		 Ensembl
RGD		 PMID:12819782 GO_REF:0000107 NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (PMID:15531758) RGD PMID:15531758 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO MGI:4822558 (PMID:21704616) RGD PMID:21704616 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830 		JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108067 (PMID:17164424)		 Ensembl
RGD		 PMID:17164424 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1926485 (PMID:16691571) RGD PMID:16691571 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Nfib nuclear factor I/B involved_in ISS
ISO		 GO_REF:0000024
(MGI:5049839|PMID:21513708)		 UniProt
RGD		 PMID:21513708 GO_REF:0000024 MGI:5049839 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107516 (PMID:17164424)		 Ensembl
RGD		 PMID:17164424 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:32484881)		 Ensembl
RGD		 PMID:32484881 GO_REF:0000107 NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular developmental process 4747
        cell differentiation 4746
          lung cell differentiation 41
            lung epithelial cell differentiation 41
              lung secretory cell differentiation 14
                lung goblet cell differentiation + 5
                lung neuroendocrine cell differentiation 1
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 20292
    developmental process 7042
      anatomical structure development 6550
        multicellular organism development 5276
          system development 4559
            respiratory system development 320
              lung development 284
                lung epithelium development 61
                  lung epithelial cell differentiation 41
                    lung secretory cell differentiation 14
                      lung goblet cell differentiation + 5
                      lung neuroendocrine cell differentiation 1
                      type II pneumocyte differentiation 8
paths to the root