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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteasomal protein catabolic process
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Accession:GO:0061136 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.


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regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:28111074)		 Ensembl
RGD		 PMID:28111074 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (MGI:3835892|PMID:19103752) RGD PMID:19103752 MGI:3835892 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Dlgap1 DLG associated protein 1 involved_in IMP PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817 		JBrowse link
G Dnaaf4 dynein axonemal assembly factor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19423554)		 UniProt
RGD		 PMID:19423554 GO_REF:0000024 NCBI chr 8:73,696,394...73,711,315
Ensembl chr 8:73,698,103...73,711,292 		JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO MGI:2182627 (MGI:5793002|PMID:27107699) RGD PMID:27107699 MGI:5793002 NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12751788)		 Ensembl
RGD		 PMID:12751788 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO MGI:3828165|MGI:6101514 (MGI:5913760|PMID:27920251), (MGI:6198859|PMID:29400713) RGD PMID:27920251 PMID:29400713 MGI:5913760 MGI:6198859 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:19419956) RGD PMID:19419956 NCBI chr15:48,707,776...48,747,363
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Pithd1 PITH domain containing 1 acts_upstream_of_or_within ISO MGI:6416147 (MGI:6392185|PMID:31915251) RGD PMID:31915251 MGI:6392185 NCBI chr 5:148,205,995...148,216,511
Ensembl chr 5:148,205,998...148,217,080 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within ISO MGI:1857562 (MGI:5461108|PMID:23001567)
(PMID:23001567)		 RGD PMID:23001567 MGI:5461108 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:17565987) RGD PMID:17565987 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 involved_in ISO (PMID:18162577) RGD PMID:18162577 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076 		JBrowse link
G Psme1 proteasome activator subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890 		JBrowse link
G Psme1-ps1 proteasome activator subunit 1, pseudogene 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:50,174,233...50,175,012
Ensembl chr17:50,174,186...50,175,160 		JBrowse link
G Psme2 proteasome activator subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946 		JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO
IBA		 (PMID:18309296)
PMID:21873635		 RGD PMID:18309296 PMID:21873635 RGD:13792537 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 involved_in ISO
ISS		 (PMID:21439629)
GO_REF:0000024		 RGD
UniProt		 PMID:21439629 GO_REF:0000024 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763 		JBrowse link
G Tmf1 TATA element modulatory factor 1 involved_in ISO (MGI:5488886|PMID:16792503) RGD PMID:16792503 MGI:5488886 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:18162577) RGD PMID:18162577 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO
IBA		 (PMID:18162577)
PMID:21873635		 RGD PMID:18162577 PMID:21873635 RGD:13792537 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO
ISS		 (PMID:23129660)
GO_REF:0000024		 RGD
UniProt		 PMID:23129660 GO_REF:0000024 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Svip small VCP interacting protein involved_in IBA
ISO
IC		 PMID:21873635
(PMID:17872946)
PMID:17000876		 RGD PMID:17872946 PMID:21873635 PMID:17000876 RGD:13792537, RGD:10047192 NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) RGD PMID:19135427 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3813160|PMID:18606867)		 UniProt
RGD		 PMID:18606867 GO_REF:0000024 MGI:3813160 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO (PMID:22590560) RGD PMID:22590560 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in ISO (PMID:8175643) RGD PMID:8175643 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G F8a1 coagulation factor VIII-associated 1 involved_in ISO
ISS		 (PMID:27815841)
GO_REF:0000024		 RGD
UniProt		 PMID:27815841 GO_REF:0000024 NCBI chr  X:150,957,357...150,958,871
Ensembl chr  X:150,916,679...150,960,168 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in IMP
ISO		 PMID:17517623
(MGI:6148636|PMID:17517623)		 RGD PMID:17517623 PMID:17517623 MGI:6148636, RGD:13514081 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 involved_in ISO (PMID:25681212) RGD PMID:25681212 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29295817)		 UniProt
RGD		 PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO
IBA		 (MGI:5303043|PMID:21874017)
PMID:21873635		 RGD PMID:21874017 PMID:21873635 MGI:5303043, RGD:13792537 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISS
ISO		 GO_REF:0000024
(MGI:5467682|PMID:23185022)		 UniProt
RGD		 PMID:23185022 GO_REF:0000024 MGI:5467682 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Psme3ip1 proteasome activator subunit 3 interacting protein 1 involved_in ISO (PMID:29934401) RGD PMID:29934401 NCBI chr19:10,401,400...10,430,059
Ensembl chr19:10,401,532...10,429,987 		JBrowse link
G Psmf1 proteasome inhibitor subunit 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10764772)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10764772 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO MGI:2176228|MGI:5758867 (MGI:5643882|PMID:25683716) RGD PMID:25683716 MGI:5643882 NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237 		JBrowse link
G Usp19 ubiquitin specific peptidase 19 involved_in ISO (MGI:5614537|PMID:25088257) RGD PMID:25088257 MGI:5614537 NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3808636|PMID:18678708)		 UniProt
Ensembl
RGD		 PMID:18678708 GO_REF:0000024 GO_REF:0000107 MGI:3808636 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Camlg calcium modulating ligand involved_in ISO UniProtKB:Q9H9V4 (PMID:20553626) RGD PMID:20553626 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23398316) RGD PMID:23398316 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28263186) RGD PMID:28263186 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H involved_in ISO (PMID:32269044) RGD PMID:32269044 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISO
ISS
IBA		 (PMID:15313915)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:15313915 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO (MGI:3807767|PMID:11546783) RGD PMID:11546783 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24613385)		 UniProt
RGD		 PMID:24613385 GO_REF:0000024 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5586592|PMID:24960163)		 RGD PMID:24960163 PMID:21873635 MGI:5586592, RGD:13792537 NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Map1a microtubule-associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) RGD PMID:26609151 MGI:5703671 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (MGI:5510937|PMID:23695157) RGD PMID:23695157 MGI:5510937 NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860 		JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in IBA
ISO		 PMID:21873635
(MGI:3829128|PMID:17592138)		 RGD PMID:17592138 PMID:21873635 MGI:3829128, RGD:13792537 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) RGD PMID:22522597 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:26678539)		 Ensembl
RGD		 PMID:26678539 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:17015834) RGD PMID:17015834 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (MGI:5293269|PMID:21715333) RGD PMID:21715333 MGI:5293269 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24492612)		 UniProt
RGD		 PMID:24492612 GO_REF:0000024 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897550|PMID:21804542)		 UniProt
RGD		 PMID:21804542 GO_REF:0000024 MGI:5897550 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rybp RING1 and YY1 binding protein involved_in ISO (PMID:27060496) RGD PMID:27060496 NCBI chr 4:132,876,361...132,927,580
NCBI chr 4:132,876,260...132,929,075
Ensembl chr 4:132,876,361...132,928,316 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO
ISS		 (PMID:25893292)
GO_REF:0000024		 RGD
UniProt		 PMID:25893292 GO_REF:0000024 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO MGI:3818522 (MGI:3818351|PMID:17981124) RGD PMID:17981124 MGI:3818351 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3624046|PMID:16611981)		 Ensembl
RGD		 PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 acts_upstream_of_or_within ISO (MGI:5310666|PMID:22285184) RGD PMID:22285184 MGI:5310666 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO
IEA		 (PMID:11278372)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278372 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tlk2 tousled-like kinase 2 involved_in ISO (PMID:20016786) RGD PMID:20016786 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in IBA
IEA
ISS
ISO		 PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:23213251)		 Ensembl
UniProt
RGD		 PMID:23213251 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (MGI:6362140|PMID:31537781) RGD PMID:31537781 MGI:6362140 NCBI chr 8:45,112,737...45,116,345 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:20351172)		 UniProt
RGD		 PMID:20351172 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23770237) RGD PMID:23770237 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISO (PMID:26678539) RGD PMID:26678539 NCBI chr10:6,880,684...6,925,033
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:33378666) RGD PMID:33378666 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pabpn1l PABPN1 like acts_upstream_of_or_within ISO (MGI:6509513|PMID:32558204) RGD PMID:32558204 MGI:6509513 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in IBA
ISO		 PMID:21873635
(PMID:28007894)		 RGD PMID:28007894 PMID:21873635 RGD:13792537 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:24089527) RGD PMID:24089527 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:18307982), (PMID:22045699) RGD PMID:18307982 PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO (PMID:23246001) RGD PMID:23246001 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18307982)		 Ensembl
UniProt
RGD		 PMID:18307982 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISO (PMID:17000876) RGD PMID:17000876 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISO
IEA		 (PMID:24424410)
GO_REF:0000107		 RGD
Ensembl		 PMID:24424410 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
ISS		 (PMID:27485036)
GO_REF:0000024		 RGD
UniProt		 PMID:27485036 GO_REF:0000024 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO
IBA		 (PMID:27485036)
PMID:21873635		 RGD PMID:27485036 PMID:21873635 RGD:13792537 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778 		JBrowse link
G Rnft2 ring finger protein, transmembrane 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:38,329,217...38,387,303
Ensembl chr12:38,329,269...38,387,290 		JBrowse link
G Tmem259 transmembrane protein 259 involved_in IBA
ISO		 PMID:21873635
(MGI:5648655|PMID:25977983)		 RGD PMID:25977983 PMID:21873635 MGI:5648655, RGD:13792537 NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932 		JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:4999711|PMID:19911006) RGD PMID:19911006 MGI:4999711 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
ISS		 (PMID:20080667)
GO_REF:0000024		 RGD
UniProt		 PMID:20080667 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:19416853)		 RGD PMID:19416853 PMID:21873635 RGD:13792537 NCBI chr18:27,309,711...27,319,106
Ensembl chr18:27,309,718...27,319,032 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5770038|PMID:24709664)		 UniProt
RGD		 PMID:24709664 GO_REF:0000024 MGI:5770038 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:22180649) RGD PMID:22180649 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO		 GO_REF:0000024
(PMID:16300740)		 UniProt
RGD		 PMID:16300740 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Osbpl7 oxysterol binding protein-like 7 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Rnf40 ring finger protein 40 IDA RGD PMID:12121982 RGD:633892 NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in ISO (PMID:21603654) RGD PMID:21603654 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6150565|PMID:29518356) RGD PMID:29518356 MGI:6150565 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) RGD PMID:21317886 MGI:4946566 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO (MGI:3589701|PMID:15937334)
(PMID:23512198)		 RGD PMID:15937334 PMID:23512198 MGI:3589701 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2446434|MGI:3587769|MGI:3691571 (MGI:5465208|PMID:23152632) RGD PMID:23152632 MGI:5465208 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Aurka aurora kinase A acts_upstream_of_or_within ISO (MGI:3697244|PMID:17060449) RGD PMID:17060449 MGI:3697244 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3628833|PMID:16601693)
PMID:21873635		 RGD PMID:16601693 PMID:21873635 MGI:3628833, RGD:13792537 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bag2 BAG cochaperone 2 NOT|involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO UniProtKB:Q99496 (PMID:22302990) RGD PMID:22302990 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:25974097) RGD PMID:25974097 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (MGI:5310666|PMID:22285184) RGD PMID:22285184 MGI:5310666 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Clu clusterin involved_in ISO
IBA
IEA
ISS		 (PMID:20068069)
PMID:21873635
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20068069 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cop1 COP1, E3 ubiquitin ligase involved_in ISO (PMID:19805145) RGD PMID:19805145 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISO (PMID:11955436), (PMID:19364825) RGD PMID:11955436 PMID:19364825 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:3849793|PMID:19414593)		 UniProt
RGD		 PMID:19414593 PMID:21873635 GO_REF:0000024 MGI:3849793, RGD:13792537 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO
IBA		 (MGI:3849793|PMID:19414593)
PMID:21873635		 RGD PMID:19414593 PMID:21873635 MGI:3849793, RGD:13792537 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12805222)		 Ensembl
RGD		 PMID:12805222 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dda1 DET1 and DDB1 associated 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IBA
ISO		 PMID:21873635
UniProtKB:Q8NHY2 (PMID:14739464)		 RGD PMID:14739464 PMID:21873635 RGD:13792537 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IBA
ISO		 PMID:21873635
(PMID:15936278)		 RGD PMID:15936278 PMID:21873635 RGD:13792537 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Fbxo22 F-box protein 22 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3840749|PMID:19319192)
PMID:21873635		 RGD PMID:19319192 PMID:21873635 MGI:3840749, RGD:13792537 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:25684205)		 UniProt
RGD		 PMID:25684205 GO_REF:0000024 NCBI chr10:54,714,834...54,717,769
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Gba glucosylceramidase beta involved_in ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2387010 (MGI:3695876|PMID:17189825) RGD PMID:17189825 MGI:3695876 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:25897075) RGD PMID:25897075 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1924375|MGI:3039600 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:22660580), (PMID:25897075)
GO_REF:0000107		 RGD
Ensembl		 PMID:19364825 PMID:22660580 PMID:25897075 GO_REF:0000107 MGI:5437589 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 involved_in ISO (PMID:16831871) RGD PMID:16831871 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861437|MGI:3039600 (MGI:5437589|PMID:22660580)		 Ensembl
RGD		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) RGD PMID:25940086 MGI:5700633 NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (MGI:4454597|PMID:20457918) RGD PMID:20457918 MGI:4454597 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 RGD PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 involved_in ISO (PMID:16707496) RGD PMID:16707496 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO
ISS		 (PMID:27588481)
GO_REF:0000024		 RGD
UniProt		 PMID:27588481 GO_REF:0000024 NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 involved_in ISO (MGI:5487503|PMID:22406621) RGD PMID:22406621 MGI:5487503 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO
ISS
IEA		 (PMID:19473992)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19473992 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:17030191)
GO_REF:0000107		 RGD
Ensembl		 PMID:17030191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IBA
ISO		 PMID:21873635
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 PMID:21873635 MGI:5543313, RGD:13792537 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
ISS		 (PMID:16023600)
GO_REF:0000024		 RGD
UniProt		 PMID:16023600 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19785988)		 UniProt
RGD		 PMID:19785988 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:26296656) RGD PMID:26296656 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO UniProtKB:Q7L5Y6 (PMID:14739464) RGD PMID:14739464 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Rnf14 ring finger protein 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685 		JBrowse link
G Rnf144a ring finger protein 144A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Rnf144b ring finger protein 144B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)		 RGD PMID:18363970 PMID:23926250 PMID:21873635 MGI:3819024 MGI:5505713, RGD:13792537 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222 		JBrowse link
G Rnf19b ring finger protein 19B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,406,085...141,431,380
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf217 ring finger protein 217 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:26,016,668...26,108,736
Ensembl chr 1:26,015,728...26,108,736 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP
IBA
ISO		 PMID:22128169
PMID:21873635
(PMID:22128169)		 RGD PMID:22128169 PMID:22128169 PMID:21873635 RGD:13673844, RGD:13792537 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5574427|PMID:24681946)		 UniProt
RGD		 PMID:24681946 GO_REF:0000024 MGI:5574427 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA		 (PMID:11278251)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278251 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:11146632) RGD PMID:11146632 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) RGD PMID:15053879 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in IBA
ISO		 PMID:21873635
(MGI:4457446|PMID:20410507)		 RGD PMID:20410507 PMID:21873635 MGI:4457446, RGD:13792537 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib2 tribbles pseudokinase 2 involved_in ISO (MGI:4457446|PMID:20410507) RGD PMID:20410507 MGI:4457446 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:19098288) RGD PMID:19098288 NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:9452483) RGD PMID:9452483 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Zer1 zyg-11 related, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 3:13,369,688...13,397,524
Ensembl chr 3:13,369,688...13,397,420 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO MGI:3664591 (MGI:3663213|PMID:16973439) RGD PMID:16973439 MGI:3663213 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677 		JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20889502)		 UniProt
RGD		 PMID:20889502 GO_REF:0000024 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
ISS		 (PMID:24681946)
GO_REF:0000024		 RGD
UniProt		 PMID:24681946 GO_REF:0000024 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw8 F-box and WD repeat domain containing 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr12:38,426,443...38,518,712
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27457971) RGD PMID:27457971 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IBA		 (MGI:5613477|PMID:15147274)
PMID:21873635		 RGD PMID:15147274 PMID:21873635 MGI:5613477, RGD:13792537 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Usp19 ubiquitin specific peptidase 19 involved_in ISO
IEA		 (PMID:25088257)
GO_REF:0000107		 RGD
Ensembl		 PMID:25088257 GO_REF:0000107 NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase involved_in ISO
ISS		 (PMID:22609986)
GO_REF:0000024		 RGD
UniProt		 PMID:22609986 GO_REF:0000024 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073 		JBrowse link
G Commd1 copper metabolism domain containing 1 involved_in ISO
IBA		 (PMID:17183367)
PMID:21873635		 RGD PMID:17183367 PMID:21873635 RGD:13792537 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501 		JBrowse link
G Desi1 desumoylating isopeptidase 1 involved_in ISO (PMID:29666234) RGD PMID:29666234 NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845 		JBrowse link
G Foxf2 forkhead box F2 involved_in ISO (PMID:29374064) RGD PMID:29374064 NCBI chr17:32,835,730...32,842,555
Ensembl chr17:32,836,777...32,842,176 		JBrowse link
G Glmn glomulin, FKBP associated protein acts_upstream_of_or_within ISO (PMID:22405651) RGD PMID:22405651 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Gna12 G protein subunit alpha 12 involved_in ISO
ISS		 (PMID:22609986)
(MGI:5448916|PMID:22609986)
GO_REF:0000024		 RGD
UniProt		 PMID:22609986 GO_REF:0000024 MGI:5448916 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:12643283) RGD PMID:12643283 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein involved_in ISO (PMID:19435460) RGD PMID:19435460 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K acts_upstream_of_or_within ISO (MGI:3806928|PMID:18710920) RGD PMID:18710920 MGI:3806928 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:15280365), (PMID:27113755) RGD PMID:15280365 PMID:27113755 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:20228063)		 RGD PMID:20228063 PMID:21873635 RGD:13792537 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO MGI:3582610 (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Xpo1 exportin 1 involved_in ISO (PMID:29666234) RGD PMID:29666234 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      catabolic process 2673
        regulation of catabolic process 1040
          regulation of protein catabolic process 371
            regulation of proteasomal protein catabolic process 196
              negative regulation of proteasomal protein catabolic process + 52
              positive regulation of proteasomal protein catabolic process + 117
              regulation of ERAD pathway + 21
              regulation of proteasomal ubiquitin-dependent protein catabolic process + 138
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      organic substance metabolic process 11557
        organonitrogen compound metabolic process 6750
          organonitrogen compound catabolic process 1374
            protein catabolic process 1043
              proteolysis involved in protein catabolic process 811
                regulation of proteolysis involved in protein catabolic process 234
                  regulation of proteasomal protein catabolic process 196
                    negative regulation of proteasomal protein catabolic process + 52
                    positive regulation of proteasomal protein catabolic process + 117
                    regulation of ERAD pathway + 21
                    regulation of proteasomal ubiquitin-dependent protein catabolic process + 138
paths to the root