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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cartilage development
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Accession:GO:0061037 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

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negative regulation of cartilage development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsk cathepsin K involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19834056) Ensembl
MGI		 PMID:19834056 GO_REF:0000107 NCBI chrNW_004936580:1,022,762...1,038,020
Ensembl chrNW_004936580:1,022,762...1,034,984 		JBrowse link
G Frzb frizzled related protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18991062) Ensembl
MGI		 PMID:18991062 GO_REF:0000107 NCBI chrNW_004936509:11,440,414...11,471,042
Ensembl chrNW_004936509:11,440,148...11,470,967 		JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chrNW_004936477:22,200,471...22,215,473
Ensembl chrNW_004936477:22,200,474...22,215,077 		JBrowse link
G Lep leptin ISO RGD PMID:19876764 RGD:5128612 NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334 		JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936490:6,262,651...6,264,069
Ensembl chrNW_004936490:6,262,785...6,263,483 		JBrowse link
G Rara retinoic acid receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936490:15,376,217...15,420,638
Ensembl chrNW_004936490:15,376,205...15,421,611 		JBrowse link
G Rarb retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885 		JBrowse link
G Rarg retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936512:10,502,954...10,524,796
Ensembl chrNW_004936512:10,500,622...10,524,824 		JBrowse link
G Tgfb2 transforming growth factor beta 2 acts_upstream_of_or_within ISO (PMID:21780244) MGI PMID:21780244 NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO (PMID:19047045) MGI PMID:19047045 NCBI chrNW_004936864:216,381...245,885
Ensembl chrNW_004936864:239,651...244,312 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101974850 refilin-B-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936564:1,495,792...1,496,447 JBrowse link
G Pthlh parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:90087) MGI
Ensembl		 PMID:90087 GO_REF:0000107 NCBI chrNW_004936760:197,525...209,212
Ensembl chrNW_004936760:197,525...209,518 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) TreeGrafter
MGI		 PMID:24436304 GO_REF:0000118 NCBI chrNW_004936538:7,226,570...7,233,203
Ensembl chrNW_004936538:7,226,570...7,233,185 		JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:7,180,262...7,483,416
Ensembl chrNW_004936518:7,180,428...7,480,802 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:36,978,555...37,025,733
Ensembl chrNW_004936471:36,978,667...37,025,773 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17481601) Ensembl
MGI		 PMID:17481601 GO_REF:0000107 NCBI chrNW_004936697:1,054,237...1,061,468
Ensembl chrNW_004936697:1,056,636...1,061,468 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:16,110,492...16,134,065
Ensembl chrNW_004936470:16,110,497...16,134,065 		JBrowse link
G Chadl chondroadherin like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:633,443...643,550
Ensembl chrNW_004936492:633,477...646,002 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16818445)
(PMID:15866163)		 Ensembl
MGI		 PMID:15866163 PMID:16818445 GO_REF:0000107 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:2,159,654...2,214,480
Ensembl chrNW_004936491:2,159,096...2,214,677 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:5,343,038...5,347,721
Ensembl chrNW_004936561:5,343,038...5,347,721 		JBrowse link
G Gli2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17328886) Ensembl
MGI		 PMID:17328886 GO_REF:0000107 NCBI chrNW_004936469:49,616,552...49,788,760
Ensembl chrNW_004936469:49,617,095...49,673,213 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16284117) Ensembl
MGI		 PMID:16284117 GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630
Ensembl chrNW_004936478:17,126,911...17,403,011 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936673:1,394,743...1,399,726
Ensembl chrNW_004936673:1,395,757...1,396,311 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16284117) Ensembl
MGI		 PMID:16284117 GO_REF:0000107 NCBI chrNW_004936569:1,474,693...1,480,562
Ensembl chrNW_004936569:1,474,665...1,480,568 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chrNW_004936599:3,902,903...3,918,471
Ensembl chrNW_004936599:3,902,897...3,918,471 		JBrowse link
G Mkx mohawk homeobox ISO RGD PMID:27370800 RGD:40924660 NCBI chrNW_004936613:2,019,815...2,083,724
Ensembl chrNW_004936613:2,019,783...2,084,267 		JBrowse link
G Nkx3-2 NK3 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:13,999,045...14,001,659
Ensembl chrNW_004936477:13,999,045...14,001,659 		JBrowse link
G Pth parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chrNW_004936528:5,081,569...5,084,030
Ensembl chrNW_004936528:5,083,596...5,084,030 		JBrowse link
G Pthlh parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:90087)
(PMID:17328886)
(PMID:8895385)		 MGI
Ensembl		 PMID:90087 PMID:8895385 PMID:17328886 GO_REF:0000107 NCBI chrNW_004936760:197,525...209,212
Ensembl chrNW_004936760:197,525...209,518 		JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936668:2,602,261...2,687,903
Ensembl chrNW_004936668:2,628,706...2,682,448 		JBrowse link
G Rarb retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885 		JBrowse link
G Rarg retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684250) Ensembl
MGI		 PMID:10684250 GO_REF:0000107 NCBI chrNW_004936512:10,502,954...10,524,796
Ensembl chrNW_004936512:10,500,622...10,524,824 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705 		JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:7,656,523...7,680,043
Ensembl chrNW_004936524:7,655,847...7,681,097 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO (PMID:16818445) MGI PMID:16818445 NCBI chrNW_004936864:216,381...245,885
Ensembl chrNW_004936864:239,651...244,312 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    negative regulation of biological process 5159
      negative regulation of multicellular organismal process 1172
        negative regulation of cartilage development 33
          negative regulation of chondrocyte differentiation + 26
Path 2
Term Annotations click to browse term
  biological_process 15969
    developmental process 6329
      anatomical structure development 5961
        multicellular organism development 4836
          system development 4211
            skeletal system development 547
              cartilage development 225
                regulation of cartilage development 72
                  negative regulation of cartilage development 33
                    negative regulation of chondrocyte differentiation + 26
paths to the root