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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of cartilage development
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Accession:GO:0061036 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

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positive regulation of cartilage development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp1 bone morphogenetic protein 1 involved_in ISO (PMID:3201241) RGD PMID:3201241 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5621263|PMID:19956691)		 Ensembl
RGD		 PMID:19956691 GO_REF:0000107 MGI:5621263 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:3201241)
GO_REF:0000107
(MGI:1353721|PMID:10684250)		 RGD
Ensembl		 PMID:3201241 PMID:10684250 GO_REF:0000107 MGI:1353721 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA		 (PMID:3201241)
GO_REF:0000107		 RGD
Ensembl		 PMID:3201241 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1195020|PMID:9441684)		 Ensembl
RGD		 PMID:9441684 GO_REF:0000107 MGI:1195020 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312 		JBrowse link
G Gdf2 growth differentiation factor 2 ISO (MGI:5621263|PMID:19956691) RGD PMID:19956691 MGI:5621263 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239 		JBrowse link
G Mdk midkine involved_in ISS
ISO		 GO_REF:0000024
(MGI:5693192|PMID:25551381)		 UniProt
RGD		 PMID:25551381 GO_REF:0000024 MGI:5693192 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Scx scleraxis bHLH transcription factor ISO (MGI:1343990|PMID:10477299) RGD PMID:10477299 MGI:1343990 NCBI chr 7:117,519,075...117,521,093
Ensembl chr 7:117,519,075...117,521,093 		JBrowse link
G Smad1 SMAD family member 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3849246|PMID:19251704)		 Ensembl
RGD		 PMID:19251704 GO_REF:0000107 MGI:3849246 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684 		JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 4:178,062,267...179,031,991
Ensembl chr 4:178,066,165...178,441,547 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21401405), (PMID:29503843)
(MGI:3839710|PMID:19047045)		 UniProt
RGD		 PMID:19047045 PMID:21401405 PMID:29503843 GO_REF:0000024 MGI:3839710 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(MGI:3823145|PMID:18991062)		 Ensembl
RGD		 PMID:18991062 GO_REF:0000107 MGI:3823145 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS		 (PMID:21547890)
GO_REF:0000024		 RGD
UniProt		 PMID:21547890 GO_REF:0000024 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 IDA RGD PMID:23077084 RGD:7242190 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in IEA
ISO		 GO_REF:0000107
MGI:95524 (MGI:3584218|PMID:15781473)		 Ensembl
RGD		 PMID:15781473 GO_REF:0000107 MGI:3584218 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273), (PMID:24098149)
MGI:1927616 (MGI:1329266|PMID:9885252), (MGI:3819026|PMID:18363966)		 RGD PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 MGI:1329266 MGI:3819026 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693 		JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
ISS		 (PMID:26643732)
GO_REF:0000024		 RGD
UniProt		 PMID:26643732 GO_REF:0000024 NCBI chr 5:23,056,345...23,072,666
Ensembl chr 5:23,056,347...23,074,599 		JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:1856276 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036 		JBrowse link
G Hoxa11 homeobox A11 ISO MGI:96203 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 4:82,296,888...82,301,419
Ensembl chr 4:82,298,152...82,300,503
Ensembl chr 4:82,298,152...82,300,503 		JBrowse link
G Hoxd11 homeobox D11 ISO MGI:96172 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 3:61,604,256...61,606,874
Ensembl chr 3:61,604,672...61,606,400 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5320274|PMID:21071451)		 Ensembl
UniProt
RGD		 PMID:21071451 GO_REF:0000024 GO_REF:0000107 MGI:5320274 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,962,737...6,964,987
Ensembl chr16:6,962,722...6,964,989 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) RGD PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr 6:6,427,657...6,436,974
Ensembl chr 6:6,427,657...6,436,974 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:17884819 RGD:2298851 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in ISO
IEA		 MGI:2176465 (MGI:1332911|PMID:10072783)
GO_REF:0000107		 RGD
Ensembl		 PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092 		JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:5285145|PMID:21035443) RGD PMID:21035443 MGI:5285145 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO
IBA		 (PMID:21401405)
PMID:21873635
(MGI:5285147|PMID:20940257)		 RGD PMID:20940257 PMID:21401405, PMID:21873635, PMID:21873635 MGI:5285147, RGD:13792537, RGD:13792537 NCBI chr 4:178,062,267...179,031,991
Ensembl chr 4:178,066,165...178,441,547 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IBA		 (PMID:21401405)
PMID:21873635
(MGI:5285147|PMID:20940257)		 RGD PMID:20940257 PMID:21401405, PMID:21873635, PMID:21873635 MGI:5285147, RGD:13792537, RGD:13792537 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:20676705), (PMID:21401405)
(MGI:4950303|PMID:21367821), (MGI:5285147|PMID:20940257)		 UniProt
RGD		 PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:4950303 MGI:5285147, RGD:13792537, RGD:13792537 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Thrb thyroid hormone receptor beta IDA RGD PMID:15647824 RGD:1601663 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS		 (PMID:21547890)
GO_REF:0000024		 RGD
UniProt		 PMID:21547890 GO_REF:0000024 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953 		JBrowse link
G Zfp219 zinc finger protein 219 ISO (MGI:5285147|PMID:20940257) RGD PMID:20940257 MGI:5285147 NCBI chr15:28,402,412...28,417,379
Ensembl chr15:28,402,415...28,406,046 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    positive regulation of biological process 6624
      positive regulation of multicellular organismal process 1654
        positive regulation of cartilage development 32
          positive regulation of chondrocyte differentiation + 21
Path 2
Term Annotations click to browse term
  biological_process 20078
    developmental process 6848
      anatomical structure development 6308
        multicellular organism development 5783
          system development 5311
            skeletal system development 555
              cartilage development 214
                regulation of cartilage development 71
                  positive regulation of cartilage development 32
                    positive regulation of chondrocyte differentiation + 21
paths to the root