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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cartilage development
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Accession:GO:0061036 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.



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positive regulation of cartilage development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp1 bone morphogenetic protein 1 acts_upstream_of_or_within ISO (PMID:3201241) RGD PMID:3201241 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO
GO_REF:0000107
(MGI:5621263|PMID:19956691)
Ensembl
RGD
PMID:19956691 GO_REF:0000107 MGI:5621263 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:3201241)
(MGI:1353721|PMID:10684250)
Ensembl
RGD
PMID:3201241 PMID:10684250 GO_REF:0000107 MGI:1353721 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:3201241)
GO_REF:0000107
RGD
Ensembl
PMID:3201241 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Ccn1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1195020|PMID:9441684)
Ensembl
RGD
PMID:9441684 GO_REF:0000107 MGI:1195020 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (MGI:5621263|PMID:19956691) RGD PMID:19956691 MGI:5621263 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Mdk midkine involved_in ISS
ISO
GO_REF:0000024
(MGI:5693192|PMID:25551381)
UniProt
RGD
PMID:25551381 GO_REF:0000024 MGI:5693192 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:1343990|PMID:10477299) RGD PMID:10477299 MGI:1343990 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626
JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3849246|PMID:19251704)
Ensembl
RGD
PMID:19251704 GO_REF:0000107 MGI:3849246 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852
JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:21401405), (PMID:29503843)
(MGI:3839710|PMID:19047045)
GO_REF:0000024
RGD
UniProt
PMID:19047045 PMID:21401405 PMID:29503843 GO_REF:0000024 MGI:3839710 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3823145|PMID:18991062)
Ensembl
RGD
PMID:18991062 GO_REF:0000107 MGI:3823145 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS
(PMID:21547890)
GO_REF:0000024
RGD
UniProt
PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 IDA RGD PMID:23077084 RGD:7242190 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:95524 (MGI:3584218|PMID:15781473)
Ensembl
RGD
PMID:15781473 GO_REF:0000107 MGI:3584218 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within
ISO (PMID:21976273), (PMID:24098149)
MGI:1927616 (MGI:1329266|PMID:9885252), (MGI:3819026|PMID:18363966)
RGD PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 MGI:1329266 MGI:3819026 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
ISS
(PMID:26643732)
GO_REF:0000024
RGD
UniProt
PMID:26643732 GO_REF:0000024 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:1856276 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5320274|PMID:21071451)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21071451 GO_REF:0000024 GO_REF:0000107 MGI:5320274 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161
JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) RGD PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:17884819 RGD:2298851 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176465 (MGI:1332911|PMID:10072783)
Ensembl
RGD
PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (MGI:5285145|PMID:21035443) RGD PMID:21035443 MGI:5285145 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO
IBA
(PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635
RGD PMID:20940257 PMID:21401405 PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852
JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IBA
(PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635
RGD PMID:20940257 PMID:21401405 PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
ISS
IBA
(PMID:20676705), (PMID:21401405)
(MGI:4950303|PMID:21367821), (MGI:5285147|PMID:20940257)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405 PMID:21873635 GO_REF:0000024 MGI:4950303 MGI:5285147, RGD:13792537 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Thrb thyroid hormone receptor beta IDA RGD PMID:15647824 RGD:1601663 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS
(PMID:21547890)
GO_REF:0000024
RGD
UniProt
PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zfp219 zinc finger protein 219 involved_in ISO (MGI:5285147|PMID:20940257) RGD PMID:20940257 MGI:5285147 NCBI chr15:24,695,831...24,710,039
Ensembl chr15:24,695,837...24,710,030
JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:6377914|PMID:29503843)
Ensembl
RGD
PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    positive regulation of biological process 6745
      positive regulation of multicellular organismal process 1679
        positive regulation of cartilage development 32
          positive regulation of chondrocyte differentiation + 21
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        multicellular organism development 5800
          system development 5439
            skeletal system development 573
              cartilage development 221
                regulation of cartilage development 73
                  positive regulation of cartilage development 32
                    positive regulation of chondrocyte differentiation + 21
paths to the root