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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004936475 10,302,091 10,384,945 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004936573 6,288,397 6,305,984 RGD:9068941
G Cnot8 CCR4-NOT transcription complex subunit 8 JBrowse link NW_004936515 7,971,504 7,988,257 RGD:9068941
G Gtpbp1 GTP binding protein 1 JBrowse link NW_004936492 2,627,881 2,648,295 RGD:9068941
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link NW_004936474 8,531,434 8,567,734 RGD:9068941
G Khsrp KH-type splicing regulatory protein JBrowse link NW_004936588 3,764,401 3,774,492 RGD:9068941
G Mov10 Mov10 RISC complex RNA helicase JBrowse link NW_004936690 1,229,249 1,254,754 RGD:9068941
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link NW_004936491 1,989,429 2,032,430 RGD:9068941
G Prr5l proline rich 5 like JBrowse link NW_004936533 1,895,594 1,975,442 RGD:9068941
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link NW_004936481 13,919,006 13,973,868 RGD:9068941
G Upf1 UPF1 RNA helicase and ATPase JBrowse link NW_004936596 2,469,444 2,505,688 RGD:9068941
G Zc3h12a zinc finger CCCH-type containing 12A JBrowse link NW_004936474 19,714,145 19,722,512 RGD:9068941
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link NW_004936592 3,321,564 3,379,015 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004936661 2,251,148 2,253,527 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004936601 2,470,021 2,616,451 RGD:9068941
G Dhx36 DEAH-box helicase 36 JBrowse link NW_004936519 1,946,684 1,987,036 RGD:9068941
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link NW_004936531 9,607,678 9,610,245 RGD:9068941
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link NW_004936738 2,096,370 2,115,135 RGD:9068941
G Khsrp KH-type splicing regulatory protein JBrowse link NW_004936588 3,764,401 3,774,492 RGD:9068941
G Mov10 Mov10 RISC complex RNA helicase JBrowse link NW_004936690 1,229,249 1,254,754 RGD:9068941
G Plekhn1 pleckstrin homology domain containing N1 JBrowse link NW_004936737 2,072,857 2,079,855 RGD:9068941
G Qki QKI, KH domain containing RNA binding JBrowse link NW_004936489 13,901,066 14,000,652 RGD:9068941
G Rbm24 RNA binding motif protein 24 JBrowse link NW_004936552 3,291,727 3,304,332 RGD:9068941
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link NW_004936481 13,919,006 13,973,868 RGD:9068941
G Tardbp TAR DNA binding protein JBrowse link NW_004936474 90,813 103,713 RGD:9068941
G Trim71 tripartite motif containing 71 JBrowse link NW_004936473 23,223,984 23,290,177 RGD:9068941
G Upf1 UPF1 RNA helicase and ATPase JBrowse link NW_004936596 2,469,444 2,505,688 RGD:9068941
G Zc3h12a zinc finger CCCH-type containing 12A JBrowse link NW_004936474 19,714,145 19,722,512 RGD:9068941
G Zc3h12d zinc finger CCCH-type containing 12D JBrowse link NW_004936489 2,454,889 2,472,392 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004936661 2,251,148 2,253,527 RGD:9068941
G Zfp36l1 ZFP36 ring finger protein like 1 JBrowse link NW_004936495 12,045,679 12,050,737 RGD:9068941
G Zfp36l2 ZFP36 ring finger protein like 2 JBrowse link NW_004936508 8,617,185 8,620,823 RGD:9068941
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex subunit 6 like JBrowse link NW_004936676 1,401,428 1,474,167 RGD:9068941
G Fto FTO alpha-ketoglutarate dependent dioxygenase JBrowse link NW_004936475 6,321,725 6,689,410 RGD:9068941
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link NW_004936525 4,301,003 4,432,125 RGD:9068941
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link NW_004936474 8,531,434 8,567,734 RGD:9068941
G Mettl14 methyltransferase like 14 JBrowse link NW_004936869 568,324 589,972 RGD:9068941
G Mettl16 methyltransferase like 16 JBrowse link NW_004936538 8,470,057 8,541,620 RGD:9068941
G Mettl3 methyltransferase like 3 JBrowse link NW_004936880 646,835 661,312 RGD:9068941
G Pum1 pumilio RNA binding family member 1 JBrowse link NW_004936474 14,243,325 14,363,461 RGD:9068941
G Rbm24 RNA binding motif protein 24 JBrowse link NW_004936552 3,291,727 3,304,332 RGD:9068941
G Rida reactive intermediate imine deaminase A homolog JBrowse link NW_004936470 44,710,481 44,721,159 RGD:9068941
G Rock1 Rho associated coiled-coil containing protein kinase 1 JBrowse link NW_004936550 730,462 874,601 RGD:9068941
G Rock2 Rho associated coiled-coil containing protein kinase 2 JBrowse link NW_004936532 7,142,580 7,284,722 RGD:9068941
G Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link NW_004936474 12,791,121 12,827,122 RGD:9068941
G Ythdf3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link NW_004936496 10,323,338 10,362,150 RGD:9068941
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl16 methyltransferase like 16 JBrowse link NW_004936538 8,470,057 8,541,620 RGD:9068941
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004936661 2,251,148 2,253,527 RGD:9068941
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004936470 10,641,109 10,690,587 RGD:9068941
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004936475 10,302,091 10,384,945 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004936573 6,288,397 6,305,984 RGD:9068941
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004936601 2,470,021 2,616,451 RGD:9068941
G Dhx36 DEAH-box helicase 36 JBrowse link NW_004936519 1,946,684 1,987,036 RGD:9068941
G Nanos2 nanos C2HC-type zinc finger 2 JBrowse link NW_004936706 2,232,265 2,232,657 RGD:9068941
G Nanos3 nanos C2HC-type zinc finger 3 JBrowse link NW_004936659 2,590,291 2,593,482 RGD:9068941
G Pabpc1 poly(A) binding protein cytoplasmic 1 JBrowse link NW_004936470 42,628,890 42,670,311 RGD:9068941
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link NW_004936492 1,461,572 1,697,500 RGD:9068941
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link NW_004936594 2,656,079 2,741,254 RGD:9068941
G Tob1 transducer of ERBB2, 1 JBrowse link NW_004936490 10,876,113 10,880,267 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004936661 2,251,148 2,253,527 RGD:9068941
G Zfp36l1 ZFP36 ring finger protein like 1 JBrowse link NW_004936495 12,045,679 12,050,737 RGD:9068941
G Zfp36l2 ZFP36 ring finger protein like 2 JBrowse link NW_004936508 8,617,185 8,620,823 RGD:9068941
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004936470 10,641,109 10,690,587 RGD:9068941
G Btg2 BTG anti-proliferation factor 2 JBrowse link NW_004936567 1,310,525 1,314,469 RGD:9068941
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004936475 10,302,091 10,384,945 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004936573 6,288,397 6,305,984 RGD:9068941
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004936601 2,470,021 2,616,451 RGD:9068941
G Pabpc1 poly(A) binding protein cytoplasmic 1 JBrowse link NW_004936470 42,628,890 42,670,311 RGD:9068941
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link NW_004936492 1,461,572 1,697,500 RGD:9068941
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link NW_004936594 2,656,079 2,741,254 RGD:9068941
G Tob1 transducer of ERBB2, 1 JBrowse link NW_004936490 10,876,113 10,880,267 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004936661 2,251,148 2,253,527 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11930
    metabolic process 7629
      catabolic process 1620
        positive regulation of catabolic process 407
          positive regulation of cellular catabolic process 350
            positive regulation of mRNA catabolic process 46
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 31
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 15
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 11930
    metabolic process 7629
      cellular metabolic process 7037
        cellular aromatic compound metabolic process 3731
          nucleobase-containing compound metabolic process 3564
            nucleic acid metabolic process 3279
              RNA metabolic process 2909
                RNA catabolic process 189
                  mRNA catabolic process 159
                    regulation of mRNA catabolic process 106
                      positive regulation of mRNA catabolic process 46
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 31
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 15
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.