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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:1624291
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Cnot8 CCR4-NOT transcription complex, subunit 8 JBrowse link 10 43,538,150 43,551,271 RGD:1624291
G Gtpbp1 GTP binding protein 1 JBrowse link 7 120,923,274 120,947,723 RGD:8553842
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 5 154,668,194 154,699,967 RGD:9854643
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1624291
RGD:1600115
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:1624291
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 14 113,530,470 113,561,645 RGD:11554176
RGD:1624291
G Prr5l proline rich 5 like JBrowse link 3 91,290,207 91,461,208 RGD:1600115
RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 4 66,012,111 66,062,160 RGD:8553432
RGD:1624291
RGD:1600115
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 29,608,588 29,611,212 RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:10042974
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1600115
RGD:1624291
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:1624291
G Plekhn1 pleckstrin homology domain containing N1 JBrowse link 5 173,646,055 173,654,140 RGD:1624291
RGD:13792537
G Qk quaking JBrowse link 1 50,983,647 51,050,692 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:13792537
RGD:1600115
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 1 1,937,620 1,972,919 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1600115
RGD:1624291
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 14 15,059,101 15,148,255 RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 9 94,425,191 94,550,431 RGD:1624291
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 5 154,668,194 154,699,967 RGD:9854643
G Mettl14 methyltransferase like 14 JBrowse link 2 227,566,811 227,583,047 RGD:1624291
G Mettl16 methyltransferase like 16 JBrowse link 10 61,626,595 61,682,947 RGD:1624291
RGD:1600115
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rida reactive intermediate imine deaminase A homolog JBrowse link 7 73,256,506 73,270,308 RGD:1600115
RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
G Ythdf1 YTH N(6)-methyladenosine RNA binding protein 1 JBrowse link 3 176,415,911 176,431,423 RGD:13792537
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
RGD:13792537
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 JBrowse link 2 100,677,388 100,711,365 RGD:1624291
RGD:13792537
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl16 methyltransferase like 16 JBrowse link 10 61,626,595 61,682,947 RGD:1624291
RGD:1600115
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1624291
RGD:1600115
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:1624291
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
G Nanos1 nanos C2HC-type zinc finger 1 JBrowse link 1 282,134,676 282,140,370 RGD:1624291
G Nanos2 nanos C2HC-type zinc finger 2 JBrowse link 1 79,894,450 79,895,910 RGD:1624291
G Nanos3 nanos C2HC-type zinc finger 3 JBrowse link 19 25,284,907 25,288,680 RGD:1624291
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 7 75,409,581 75,421,874 RGD:1624291
RGD:1600115
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link 7 121,930,610 122,147,934 RGD:1624291
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link 10 106,698,359 106,763,639 RGD:1624291
G Tob1 transducer of ErbB-2.1 JBrowse link 10 81,913,689 81,915,727 RGD:1624291
RGD:1600115
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:11344945
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
RGD:1624291
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:1624291
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:1624291
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 7 75,409,581 75,421,874 RGD:1624291
RGD:1600115
G Polr2g RNA polymerase II subunit G JBrowse link 1 224,991,250 224,998,355 RGD:13792537
G Tnrc6a trinucleotide repeat containing adaptor 6A JBrowse link 1 192,991,584 193,146,403 RGD:13792537
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link 7 121,930,610 122,147,934 RGD:1624291
RGD:13792537
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link 10 106,698,359 106,763,639 RGD:1624291
RGD:13792537
G Tob1 transducer of ErbB-2.1 JBrowse link 10 81,913,689 81,915,727 RGD:1600115
RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      catabolic process 2515
        positive regulation of catabolic process 479
          positive regulation of cellular catabolic process 411
            positive regulation of mRNA catabolic process 50
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 32
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                RNA catabolic process 261
                  mRNA catabolic process 225
                    regulation of mRNA catabolic process 129
                      positive regulation of mRNA catabolic process 50
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 32
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.