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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 6 20,271,593 20,372,300 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 17 4,934,379 4,950,093 RGD:9068941
G CNOT8 CCR4-NOT transcription complex subunit 8 JBrowse link 16 68,329,785 68,352,020 RGD:14298760
G GTPBP1 GTP binding protein 1 JBrowse link 5 9,294,329 9,322,192 RGD:9068941
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 6 81,203,067 81,239,823 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 2 72,656,951 72,668,854 RGD:9068941
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 4 107,738,089 107,763,873 RGD:9068941
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 3 85,595,356 85,639,665 RGD:14298760
G PRR5L proline rich 5 like JBrowse link 2 24,646,865 24,812,642 RGD:14298760
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 9 116,204,807 116,292,455 RGD:9068941
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 2 58,975,013 59,013,546 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 6 93,541,334 93,551,200 RGD:9068941
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 18 10,529,805 10,588,913 RGD:14298760
G ZFP36 ZFP36 ring finger protein JBrowse link 6 48,063,732 48,066,235 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 14 103,675,164 103,871,245 RGD:14298760
G DHX36 DEAH-box helicase 36 JBrowse link 13 94,298,790 94,350,333 RGD:14298760
G DND1 DND microRNA-mediated repression inhibitor 1 JBrowse link 2 142,384,526 142,387,407 RGD:14298760
G HNRNPD heterogeneous nuclear ribonucleoprotein D JBrowse link 8 135,844,492 135,862,633 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 2 72,656,951 72,668,854 RGD:9068941
G KLHL17 kelch like family member 17 JBrowse link 6 63,320,898 63,328,093 RGD:14298760
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 4 107,738,089 107,763,873 RGD:14298760
G PLEKHN1 pleckstrin homology domain containing N1 JBrowse link 6 63,328,054 63,336,140 RGD:14298760
G QKI QKI, KH domain containing RNA binding JBrowse link 1 4,732,575 4,883,386 RGD:9068941
G RBM24 RNA binding motif protein 24 JBrowse link 7 13,126,518 13,139,504 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 9 116,204,807 116,292,455 RGD:14298760
G TARDBP TAR DNA binding protein JBrowse link 6 71,213,584 71,227,707 RGD:14298760
G TRIM71 tripartite motif containing 71 JBrowse link 13 18,762,043 18,835,788 RGD:14298760
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 2 58,975,013 59,013,546 RGD:14298760
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 6 93,541,334 93,551,200 RGD:14298760
G ZC3H12D zinc finger CCCH-type containing 12D JBrowse link 1 16,463,532 16,498,974 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 6 48,063,732 48,066,235 RGD:14298760
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 7 92,490,069 92,495,864 RGD:14298760
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 3 97,200,395 97,203,094 RGD:9068941
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT6L CCR4-NOT transcription complex subunit 6 like JBrowse link 8 73,191,721 73,335,779 RGD:14298760
G FTO FTO alpha-ketoglutarate dependent dioxygenase JBrowse link 6 31,177,112 31,564,674 RGD:14298760
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 15 133,180,638 133,313,307 RGD:14298760
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 6 81,203,067 81,239,823 RGD:9068941
G METTL14 methyltransferase like 14 JBrowse link 8 105,019,539 105,053,603 RGD:14298760
G METTL16 methyltransferase like 16 JBrowse link 12 48,491,254 48,567,253 RGD:14298760
G METTL3 methyltransferase like 3 JBrowse link 7 77,661,945 77,679,459 RGD:9068941
G PUM1 pumilio RNA binding family member 1 JBrowse link 6 87,546,388 87,687,483 RGD:14298760
G RBM24 RNA binding motif protein 24 JBrowse link 7 13,126,518 13,139,504 RGD:9068941
G RIDA reactive intermediate imine deaminase A homolog JBrowse link 4 38,656,270 38,665,863 RGD:14298760
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 6 106,163,899 106,314,998 RGD:14298760
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 3 125,353,063 125,493,368 RGD:9068941
G YTHDF1 YTH N6-methyladenosine RNA binding protein 1 JBrowse link 17 62,329,302 62,341,312 RGD:14298760
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 6 85,717,147 85,756,750 RGD:14298760
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link 4 70,887,101 70,928,839 RGD:14298760
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL16 methyltransferase like 16 JBrowse link 12 48,491,254 48,567,253 RGD:14298760
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFP36 ZFP36 ring finger protein JBrowse link 6 48,063,732 48,066,235 RGD:9068941
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 4 2,966,794 3,012,388 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 6 20,271,593 20,372,300 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 17 4,934,379 4,950,093 RGD:9068941
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 14 103,675,164 103,871,245 RGD:9068941
G DHX36 DEAH-box helicase 36 JBrowse link 13 94,298,790 94,350,333 RGD:14298760
G NANOS1 nanos C2HC-type zinc finger 1 JBrowse link 14 128,962,311 128,964,207 RGD:14298760
G NANOS2 nanos C2HC-type zinc finger 2 JBrowse link 6 52,218,889 52,219,834 RGD:14298760
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 4 36,137,644 36,228,075 RGD:9068941
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 5 8,052,434 8,311,811 RGD:9068941
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 12 3,847,522 3,939,054 RGD:9068941
G TOB1 transducer of ERBB2, 1 JBrowse link 12 27,116,579 27,119,906 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 6 48,063,732 48,066,235 RGD:9068941
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 7 92,490,069 92,495,864 RGD:9068941
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 3 97,200,395 97,203,094 RGD:9068941
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 4 2,966,794 3,012,388 RGD:9068941
G BTG2 BTG anti-proliferation factor 2 JBrowse link 9 64,033,853 64,037,795 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 6 20,271,593 20,372,300 RGD:14298760
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 17 4,934,379 4,950,093 RGD:14298760
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 14 103,675,164 103,871,245 RGD:14298760
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 4 36,137,644 36,228,075 RGD:9068941
G POLR2G RNA polymerase II subunit G JBrowse link 2 9,004,388 9,008,631 RGD:14298760
G TNRC6A trinucleotide repeat containing adaptor 6A RGD:14298760
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 5 8,052,434 8,311,811 RGD:14298760
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 12 3,847,522 3,939,054 RGD:14298760
G TOB1 transducer of ERBB2, 1 JBrowse link 12 27,116,579 27,119,906 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 6 48,063,732 48,066,235 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      catabolic process 2177
        positive regulation of catabolic process 455
          positive regulation of cellular catabolic process 386
            positive regulation of mRNA catabolic process 50
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 33
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 17
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      cellular metabolic process 9428
        cellular aromatic compound metabolic process 4993
          nucleobase-containing compound metabolic process 4795
            nucleic acid metabolic process 4388
              RNA metabolic process 3922
                RNA catabolic process 247
                  mRNA catabolic process 212
                    regulation of mRNA catabolic process 128
                      positive regulation of mRNA catabolic process 50
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 33
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 17
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.