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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 8 95,718,931 95,808,113 RGD:2290270
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 8 40,492,538 40,515,847 RGD:2290270
G Cnot8 CCR4-NOT transcription complex, subunit 8 JBrowse link 11 58,092,794 58,118,597 RGD:2290270
G Gtpbp1 GTP binding protein 1 JBrowse link 15 79,690,001 79,721,479 RGD:2290270
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 4 136,310,942 136,345,981 RGD:2290270
G Khsrp KH-type splicing regulatory protein JBrowse link 17 57,021,049 57,031,507 RGD:2290270
G Mir7578 microRNA 7578 JBrowse link 2 27,450,549 27,450,630 RGD:2290270
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 3 104,794,828 104,818,619 RGD:2290270
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 11 29,130,129 29,161,827 RGD:2290270
G Prr5l proline rich 5 like JBrowse link 2 101,713,110 101,883,052 RGD:2290270
G Rc3h1 RING CCCH (C3H) domains 1 JBrowse link 1 160,906,411 160,974,976 RGD:2290270
G Upf1 UPF1 regulator of nonsense transcripts homolog (yeast) JBrowse link 8 70,331,493 70,353,423 RGD:2290270
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 4 125,118,414 125,127,881 RGD:2290270
G Zc3hav1 zinc finger CCCH type, antiviral 1 JBrowse link 6 38,305,286 38,355,352 RGD:2290270
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 19 37,019,341 37,207,620 RGD:2290270
G Dhx36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 JBrowse link 3 62,468,015 62,507,034 RGD:2290270
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 36,763,671 36,766,214 RGD:2290270
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 5 99,955,935 99,979,130 RGD:2290270
G Khsrp KH-type splicing regulatory protein JBrowse link 17 57,021,049 57,031,507 RGD:2290270
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 3 104,794,828 104,818,619 RGD:2290270
G Plekhn1 pleckstrin homology domain containing, family N member 1 JBrowse link 4 156,221,456 156,228,542 RGD:2290270
G Qk quaking JBrowse link 17 10,206,471 10,319,361 RGD:2290270
G Rbm24 RNA binding motif protein 24 JBrowse link 13 46,418,102 46,431,099 RGD:2290270
G Rc3h1 RING CCCH (C3H) domains 1 JBrowse link 1 160,906,411 160,974,976 RGD:2290270
G Tardbp TAR DNA binding protein JBrowse link 4 148,612,382 148,627,084 RGD:2290270
G Trim71 tripartite motif-containing 71 JBrowse link 9 114,511,268 114,564,369 RGD:2290270
G Upf1 UPF1 regulator of nonsense transcripts homolog (yeast) JBrowse link 8 70,331,493 70,353,423 RGD:2290270
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 4 125,118,414 125,127,881 RGD:2290270
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 10 7,832,323 7,870,397 RGD:2290270
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 12 80,107,760 80,113,013 RGD:2290270
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 17 84,183,924 84,187,947 RGD:2290270
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 5 96,070,333 96,164,198 RGD:2290270
G Fto fat mass and obesity associated JBrowse link 8 91,313,367 91,668,433 RGD:2290270
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 1 87,326,931 87,450,810 RGD:2290270
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 4 136,310,942 136,345,981 RGD:2290270
G Mettl14 methyltransferase like 14 JBrowse link 3 123,368,295 123,385,990 RGD:2290270
G Mettl16 methyltransferase like 16 JBrowse link 11 74,770,815 74,826,855 RGD:2290270
G Mettl3 methyltransferase like 3 JBrowse link 14 52,294,841 52,308,741 RGD:2290270
G Mex3d mex3 RNA binding family member D JBrowse link 10 80,380,355 80,387,651 RGD:2290270
G Pum1 pumilio RNA-binding family member 1 JBrowse link 4 130,663,238 130,781,564 RGD:2290270
G Rbm24 RNA binding motif protein 24 JBrowse link 13 46,418,102 46,431,099 RGD:2290270
G Rida reactive intermediate imine deaminase A homolog JBrowse link 15 34,484,022 34,495,246 RGD:2290270
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 10,064,401 10,182,251 RGD:2290270
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 12 16,894,978 16,988,274 RGD:2290270
G Ythdf1 YTH N6-methyladenosine RNA binding protein 1 JBrowse link 2 180,904,377 180,920,936 RGD:2290270
G Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 4 132,184,916 132,212,256 RGD:2290270
G Ythdf3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link 3 16,183,148 16,217,037 RGD:2290270
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl16 methyltransferase like 16 JBrowse link 11 74,770,815 74,826,855 RGD:2290270
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic subunit 2 JBrowse link 15 73,101,625 73,184,947 RGD:2290270
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 8 95,718,931 95,808,113 RGD:2290270
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 8 40,492,538 40,515,847 RGD:2290270
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 19 37,019,341 37,207,620 RGD:2290270
G Dhx36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 JBrowse link 3 62,468,015 62,507,034 RGD:2290270
G Nanos1 nanos C2HC-type zinc finger 1 JBrowse link 19 60,755,987 60,759,914 RGD:2290270
G Nanos2 nanos C2HC-type zinc finger 2 JBrowse link 7 18,987,524 18,988,962 RGD:2290270
G Nanos3 nanos C2HC-type zinc finger 3 JBrowse link 8 84,173,733 84,176,552 RGD:2290270
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 15 36,595,658 36,609,581 RGD:2290270
G Tnrc6b trinucleotide repeat containing 6b JBrowse link 15 80,711,313 80,941,086 RGD:2290270
G Tnrc6c trinucleotide repeat containing 6C JBrowse link 11 117,653,703 117,763,439 RGD:2290270
G Tob1 transducer of ErbB-2.1 JBrowse link 11 94,209,842 94,215,495 RGD:2290270
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 12 80,107,760 80,113,013 RGD:2290270
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 17 84,183,924 84,187,947 RGD:2290270
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic subunit 2 JBrowse link 15 73,101,625 73,184,947 RGD:2290270
G Btg2 BTG anti-proliferation factor 2 JBrowse link 1 134,074,865 134,079,155 RGD:2290270
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 8 95,718,931 95,808,113 RGD:2290270
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 8 40,492,538 40,515,847 RGD:2290270
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 19 37,019,341 37,207,620 RGD:2290270
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 15 36,595,658 36,609,581 RGD:2290270
G Polr2g polymerase (RNA) II (DNA directed) polypeptide G JBrowse link 19 8,793,129 8,798,557 RGD:2290270
G Tnrc6a trinucleotide repeat containing 6a JBrowse link 7 123,031,101 123,195,296 RGD:2290270
G Tnrc6b trinucleotide repeat containing 6b JBrowse link 15 80,711,313 80,941,086 RGD:2290270
G Tnrc6c trinucleotide repeat containing 6C JBrowse link 11 117,653,703 117,763,439 RGD:2290270
G Tob1 transducer of ErbB-2.1 JBrowse link 11 94,209,842 94,215,495 RGD:2290270
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23311
    metabolic process 11217
      catabolic process 2388
        positive regulation of catabolic process 471
          positive regulation of cellular catabolic process 401
            positive regulation of mRNA catabolic process 52
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 33
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 23311
    metabolic process 11217
      cellular metabolic process 10030
        cellular aromatic compound metabolic process 5395
          nucleobase-containing compound metabolic process 5166
            nucleic acid metabolic process 4728
              RNA metabolic process 4245
                RNA catabolic process 262
                  mRNA catabolic process 224
                    regulation of mRNA catabolic process 128
                      positive regulation of mRNA catabolic process 52
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 33
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.