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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 58,519,951 58,629,826 RGD:2290271
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 17,221,981 17,246,909 RGD:2290271
G CNOT8 CCR4-NOT transcription complex subunit 8 JBrowse link 5 154,857,952 154,876,792 RGD:2290271
G GTPBP1 GTP binding protein 1 JBrowse link 22 38,704,561 38,738,265 RGD:2290271
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 1 23,304,688 23,344,316 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 19 6,413,102 6,424,811 RGD:2290271
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 1 112,674,312 112,702,377 RGD:2290271
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 2 55,634,061 55,693,853 RGD:2290271
G PRR5L proline rich 5 like JBrowse link 11 36,296,288 36,465,204 RGD:2290271
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 173,931,084 174,022,357 RGD:2290271
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 19 18,831,405 18,868,230 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 7 139,043,515 139,109,720 RGD:2290271
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 92,046,692 92,291,499 RGD:2290271
G DHX36 DEAH-box helicase 36 JBrowse link 3 154,272,546 154,324,497 RGD:2290271
G DND1 DND microRNA-mediated repression inhibitor 1 JBrowse link 5 140,670,794 140,673,576 RGD:2290271
G HNRNPD heterogeneous nuclear ribonucleoprotein D JBrowse link 4 82,352,498 82,373,996 RGD:2290271
G KHSRP KH-type splicing regulatory protein JBrowse link 19 6,413,102 6,424,811 RGD:2290271
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 1 112,674,312 112,702,377 RGD:2290271
G PLEKHN1 pleckstrin homology domain containing N1 JBrowse link 1 965,820 975,865 RGD:2290271
G QKI QKI, KH domain containing RNA binding JBrowse link 6 163,414,486 163,578,592 RGD:9068941
G RBM24 RNA binding motif protein 24 JBrowse link 6 17,281,361 17,293,875 RGD:2290271
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 173,931,084 174,022,357 RGD:2290271
G TARDBP TAR DNA binding protein JBrowse link 1 11,012,654 11,030,528 RGD:2290271
G TRIM71 tripartite motif containing 71 JBrowse link 3 32,817,997 32,897,824 RGD:2290271
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 19 18,831,405 18,868,230 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
G ZC3H12D zinc finger CCCH-type containing 12D JBrowse link 6 149,446,795 149,485,014 RGD:2290271
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:2290271
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 14 68,787,655 68,796,243 RGD:2290271
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 2 43,222,402 43,226,606 RGD:2290271
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT6L CCR4-NOT transcription complex subunit 6 like JBrowse link 4 77,713,387 77,820,269 RGD:2290271
G FTO FTO alpha-ketoglutarate dependent dioxygenase JBrowse link 16 53,703,963 54,121,941 RGD:2290271
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 2 232,697,331 232,860,605 RGD:2290271
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 1 23,304,688 23,344,316 RGD:2290271
G METTL14 methyltransferase like 14 JBrowse link 4 118,685,375 118,715,430 RGD:2290271
G METTL16 methyltransferase like 16 JBrowse link 17 2,416,049 2,511,901 RGD:2290271
G METTL3 methyltransferase like 3 JBrowse link 14 21,498,138 21,511,340 RGD:2290271
G MEX3D mex-3 RNA binding family member D JBrowse link 19 1,554,669 1,568,325 RGD:2290271
G PUM1 pumilio RNA binding family member 1 JBrowse link 1 30,931,506 31,065,717 RGD:2290271
G RBM24 RNA binding motif protein 24 JBrowse link 6 17,281,361 17,293,875 RGD:2290271
G RIDA reactive intermediate imine deaminase A homolog JBrowse link 8 98,102,344 98,117,171 RGD:2290271
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 18 20,946,906 21,111,813 RGD:2290271
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2 11,179,759 11,345,437 RGD:2290271
G YTHDF1 YTH N6-methyladenosine RNA binding protein 1 JBrowse link 20 63,195,429 63,216,131 RGD:2290271
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 1 28,736,621 28,769,775 RGD:2290271
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link 8 63,168,553 63,212,788 RGD:2290271
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL16 methyltransferase like 16 JBrowse link 17 2,416,049 2,511,901 RGD:2290271
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:2290271
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 140,520,156 140,642,406 RGD:2290271
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 58,519,951 58,629,826 RGD:2290271
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 17,221,981 17,246,909 RGD:2290271
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 92,046,692 92,291,499 RGD:2290271
G DHX36 DEAH-box helicase 36 JBrowse link 3 154,272,546 154,324,497 RGD:2290271
G NANOS1 nanos C2HC-type zinc finger 1 JBrowse link 10 119,029,714 119,033,730 RGD:2290271
G NANOS2 nanos C2HC-type zinc finger 2 JBrowse link 19 45,913,214 45,914,778 RGD:2290271
G NANOS3 nanos C2HC-type zinc finger 3 JBrowse link 19 13,862,036 13,880,757 RGD:2290271
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 8 100,702,916 100,722,088 RGD:2290271
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 22 40,044,817 40,335,808 RGD:2290271
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 17 77,958,853 78,108,835 RGD:2290271
G TOB1 transducer of ERBB2, 1 JBrowse link 17 50,862,223 50,867,978 RGD:2290271
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:2290271
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 14 68,787,655 68,796,243 RGD:2290271
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 2 43,222,402 43,226,606 RGD:2290271
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 140,520,156 140,642,406 RGD:2290271
G BTG2 BTG anti-proliferation factor 2 JBrowse link 1 203,305,519 203,309,602 RGD:2290271
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 58,519,951 58,629,826 RGD:2290271
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 17,221,981 17,246,909 RGD:2290271
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 92,046,692 92,291,499 RGD:2290271
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 8 100,702,916 100,722,088 RGD:2290271
G POLR2G RNA polymerase II subunit G JBrowse link 11 62,761,580 62,766,710 RGD:2290271
G TNRC6A trinucleotide repeat containing adaptor 6A JBrowse link 16 24,610,205 24,826,223 RGD:2290271
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 22 40,044,817 40,335,808 RGD:2290271
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 17 77,958,853 78,108,835 RGD:2290271
G TOB1 transducer of ERBB2, 1 JBrowse link 17 50,862,223 50,867,978 RGD:2290271
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18542
    metabolic process 12199
      catabolic process 2833
        positive regulation of catabolic process 494
          positive regulation of cellular catabolic process 419
            positive regulation of mRNA catabolic process 51
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 33
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 18542
    metabolic process 12199
      cellular metabolic process 11192
        cellular aromatic compound metabolic process 6143
          nucleobase-containing compound metabolic process 5895
            nucleic acid metabolic process 5350
              RNA metabolic process 4826
                RNA catabolic process 432
                  mRNA catabolic process 390
                    regulation of mRNA catabolic process 217
                      positive regulation of mRNA catabolic process 51
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 33
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.