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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 2 58,038,456 58,138,364 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 16 40,554,214 40,571,841 RGD:9068941
G CNOT8 CCR4-NOT transcription complex subunit 8 JBrowse link 4 54,935,476 54,956,000 RGD:13508589
G GTPBP1 GTP binding protein 1 JBrowse link 10 26,074,969 26,103,520 RGD:9068941
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 2 76,073,553 76,108,763 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 20 53,746,656 53,755,388 RGD:9068941
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 17 62,872,607 62,896,208 RGD:9068941
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 10 56,478,771 56,520,992 RGD:13508589
G PRR5L proline rich 5 like JBrowse link 18 31,708,888 31,849,365 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 7 25,265,836 25,312,417 RGD:9068941
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 20 44,234,411 44,271,129 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 15 4,972,369 4,984,218 RGD:9068941
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 16 9,598,339 9,660,540 RGD:13508589
G ZFP36 ZFP36 ring finger protein JBrowse link 1 113,815,972 113,818,093 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 28 6,523,894 6,724,010 RGD:9068941
G DHX36 DEAH-box helicase 36 JBrowse link 23 48,404,351 48,456,360 RGD:13508589
G DND1 DND microRNA-mediated repression inhibitor 1 JBrowse link 2 35,825,154 35,827,913 RGD:13508589
G HNRNPD heterogeneous nuclear ribonucleoprotein D JBrowse link 32 6,323,444 6,341,238 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 20 53,746,656 53,755,388 RGD:13508589
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 17 62,872,607 62,896,208 RGD:9068941
G PLEKHN1 pleckstrin homology domain containing N1 JBrowse link 5 56,193,824 56,202,340 RGD:13508589
G QKI QKI, KH domain containing RNA binding JBrowse link 1 51,800,294 51,956,891 RGD:9068941
G RBM24 RNA binding motif protein 24 JBrowse link 35 16,255,076 16,294,967 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 7 25,265,836 25,312,417 RGD:13508589
G TARDBP TAR DNA binding protein JBrowse link 2 84,987,752 84,998,136 RGD:13508589
G TRIM71 tripartite motif containing 71 JBrowse link 23 3,888,287 3,959,910 RGD:13508589
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 20 44,234,411 44,271,129 RGD:13508589
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 15 4,972,369 4,984,218 RGD:13508589
G ZC3H12D zinc finger CCCH-type containing 12D JBrowse link 1 40,249,856 40,279,344 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 1 113,815,972 113,818,093 RGD:13508589
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 8 42,663,287 42,668,665 RGD:13508589
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 10 45,746,952 45,751,268 RGD:13508589
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT6L CCR4-NOT transcription complex subunit 6 like JBrowse link 32 2,192,800 2,305,526 RGD:13508589
G FTO FTO alpha-ketoglutarate dependent dioxygenase JBrowse link 2 61,699,864 62,080,199 RGD:9068941
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 25 44,317,540 44,453,761 RGD:13508589
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 2 76,073,553 76,108,763 RGD:9068941
G METTL14 methyltransferase like 14 JBrowse link 32 37,653,163 37,679,577 RGD:13508589
G METTL16 methyltransferase like 16 JBrowse link 9 46,491,503 46,566,752 RGD:13508589
G METTL3 methyltransferase like 3 JBrowse link 15 18,528,755 18,546,303 RGD:9068941
G PUM1 pumilio RNA binding family member 1 JBrowse link 2 69,907,655 70,044,055 RGD:13508589
G RBM24 RNA binding motif protein 24 JBrowse link 35 16,255,076 16,294,967 RGD:9068941
G RIDA reactive intermediate imine deaminase A homolog JBrowse link 13 348,744 361,063 RGD:13508589
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 7 66,862,614 67,001,538 RGD:9068941
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 17 7,931,786 8,012,484 RGD:9068941
G YTHDF1 YTH N6-methyladenosine RNA binding protein 1 JBrowse link 24 46,927,218 46,940,015 RGD:13508589
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 2 71,760,232 71,791,420 RGD:13508589
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link 29 13,239,900 13,280,035 RGD:9068941
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL16 methyltransferase like 16 JBrowse link 9 46,491,503 46,566,752 RGD:13508589
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFP36 ZFP36 ring finger protein JBrowse link 1 113,815,972 113,818,093 RGD:9068941
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 13 35,169,243 35,230,252 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 2 58,038,456 58,138,364 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 16 40,554,214 40,571,841 RGD:9068941
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 28 6,523,894 6,724,010 RGD:9068941
G DHX36 DEAH-box helicase 36 JBrowse link 23 48,404,351 48,456,360 RGD:13508589
G NANOS1 nanos C2HC-type zinc finger 1 JBrowse link 28 29,285,422 29,287,236 RGD:9068941
G NANOS2 nanos C2HC-type zinc finger 2 JBrowse link 1 109,716,634 109,717,701 RGD:13508589
G NANOS3 nanos C2HC-type zinc finger 3 RGD:13508589
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 13 2,563,698 2,580,610 RGD:9068941
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 10 24,852,168 25,094,400 RGD:9068941
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 9 3,018,599 3,122,664 RGD:9068941
G TOB1 transducer of ERBB2, 1 JBrowse link 9 26,736,805 26,741,119 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 1 113,815,972 113,818,093 RGD:9068941
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 8 42,663,287 42,668,665 RGD:9068941
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 10 45,746,952 45,751,268 RGD:13508589
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 13 35,169,243 35,230,252 RGD:9068941
G BTG2 BTG anti-proliferation factor 2 JBrowse link 38 70,921 75,149 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 2 58,038,456 58,138,364 RGD:13508589
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 16 40,554,214 40,571,841 RGD:13508589
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 28 6,523,894 6,724,010 RGD:9068941
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 13 2,563,698 2,580,610 RGD:9068941
G POLR2G RNA polymerase II subunit G JBrowse link 18 53,916,431 53,919,724 RGD:13508589
G TNRC6A trinucleotide repeat containing adaptor 6A JBrowse link 6 21,247,492 21,454,424 RGD:13508589
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 10 24,852,168 25,094,400 RGD:13508589
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 9 3,018,599 3,122,664 RGD:13508589
G TOB1 transducer of ERBB2, 1 JBrowse link 9 26,736,805 26,741,119 RGD:13508589
G ZFP36 ZFP36 ring finger protein JBrowse link 1 113,815,972 113,818,093 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16041
    metabolic process 10496
      catabolic process 2192
        positive regulation of catabolic process 454
          positive regulation of cellular catabolic process 384
            positive regulation of mRNA catabolic process 50
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 32
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 16041
    metabolic process 10496
      cellular metabolic process 9494
        cellular aromatic compound metabolic process 4995
          nucleobase-containing compound metabolic process 4798
            nucleic acid metabolic process 4363
              RNA metabolic process 3906
                RNA catabolic process 249
                  mRNA catabolic process 216
                    regulation of mRNA catabolic process 129
                      positive regulation of mRNA catabolic process 50
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 32
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 18
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.