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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004955433 15,938,791 16,027,547 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004955463 285,228 306,077 RGD:9068941
G Cnot8 CCR4-NOT transcription complex subunit 8 JBrowse link NW_004955408 9,112,208 9,132,650 RGD:9068941
G Gtpbp1 GTP binding protein 1 JBrowse link NW_004955413 24,823,113 24,849,522 RGD:9068941
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link NW_004955452 3,318,536 3,354,725 RGD:9068941
G Khsrp KH-type splicing regulatory protein JBrowse link NW_004955495 3,183,083 3,194,356 RGD:9068941
G Mov10 Mov10 RISC complex RNA helicase JBrowse link NW_004955435 16,093,471 16,114,735 RGD:9068941
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link NW_004955424 27,407,451 27,449,830 RGD:9068941
G Prr5l proline rich 5 like JBrowse link NW_004955422 9,972,588 10,069,411 RGD:9068941
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link NW_004955406 14,053,122 14,123,023 RGD:9068941
G Upf1 UPF1 RNA helicase and ATPase JBrowse link NW_004955524 2,798,336 2,814,063 RGD:9068941
G Zc3h12a zinc finger CCCH-type containing 12A JBrowse link NW_004955452 15,306,398 15,314,959 RGD:9068941
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link NW_004955494 3,925,478 3,985,469 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004955468 152,744 155,140 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004955425 1,032,446 1,224,300 RGD:9068941
G Dhx36 DEAH-box helicase 36 JBrowse link NW_004955448 5,634,072 5,676,272 RGD:9068941
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link NW_004955418 30,795 33,394 RGD:9068941
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link NW_004955433 6,452,931 6,470,209 RGD:9068941
G Khsrp KH-type splicing regulatory protein JBrowse link NW_004955495 3,183,083 3,194,356 RGD:9068941
G Mov10 Mov10 RISC complex RNA helicase JBrowse link NW_004955435 16,093,471 16,114,735 RGD:9068941
G Plekhn1 pleckstrin homology domain containing N1 JBrowse link NW_004955486 9,736,801 9,744,659 RGD:9068941
G Qki QKI, KH domain containing RNA binding JBrowse link NW_004955439 17,925,205 18,079,727 RGD:9068941
G Rbm24 RNA binding motif protein 24 JBrowse link NW_004955483 8,705,533 8,716,772 RGD:9068941
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link NW_004955406 14,053,122 14,123,023 RGD:9068941
G Tardbp TAR DNA binding protein JBrowse link NW_004955486 2,656,121 2,674,808 RGD:9068941
G Trim71 tripartite motif containing 71 JBrowse link NW_004955421 97,130 174,326 RGD:9068941
G Upf1 UPF1 RNA helicase and ATPase JBrowse link NW_004955524 2,798,336 2,814,063 RGD:9068941
G Zc3h12a zinc finger CCCH-type containing 12A JBrowse link NW_004955452 15,306,398 15,314,959 RGD:9068941
G Zc3h12d zinc finger CCCH-type containing 12D JBrowse link NW_004955439 11,761,099 11,787,508 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004955468 152,744 155,140 RGD:9068941
G Zfp36l1 ZFP36 ring finger protein like 1 JBrowse link NW_004955466 1,541,367 1,546,617 RGD:9068941
G Zfp36l2 ZFP36 ring finger protein like 2 JBrowse link NW_004955441 10,467,608 10,469,885 RGD:9068941
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex subunit 6 like JBrowse link NW_004955433 2,206,462 2,290,773 RGD:9068941
G Fto FTO alpha-ketoglutarate dependent dioxygenase JBrowse link NW_004955433 11,424,069 11,834,955 RGD:9068941
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link NW_004955453 3,201,593 3,301,541 RGD:9068941
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link NW_004955452 3,318,536 3,354,725 RGD:9068941
G Mettl14 methyltransferase like 14 JBrowse link NW_004955428 21,475,981 21,507,730 RGD:9068941
G Mettl16 methyltransferase like 16 JBrowse link NW_004955481 762,030 836,299 RGD:9068941
G Mettl3 methyltransferase like 3 JBrowse link NW_004955550 2,211,270 2,227,715 RGD:9068941
G Pum1 pumilio RNA binding family member 1 JBrowse link NW_004955452 9,487,725 9,623,565 RGD:9068941
G Rbm24 RNA binding motif protein 24 JBrowse link NW_004955483 8,705,533 8,716,772 RGD:9068941
G Rida reactive intermediate imine deaminase A homolog JBrowse link NW_004955417 13,810,596 13,822,982 RGD:9068941
G Rock1 Rho associated coiled-coil containing protein kinase 1 JBrowse link NW_004955402 9,752,101 9,864,317 RGD:9068941
G Rock2 Rho associated coiled-coil containing protein kinase 2 JBrowse link NW_004955487 5,856,190 5,972,408 RGD:9068941
G Ythdf2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link NW_004955452 7,783,398 7,815,468 RGD:9068941
G Ythdf3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link NW_004955444 15,758,596 15,789,979 RGD:9068941
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl16 methyltransferase like 16 JBrowse link NW_004955481 762,030 836,299 RGD:9068941
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004955468 152,744 155,140 RGD:9068941
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004955461 14,194,268 14,260,949 RGD:9068941
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004955433 15,938,791 16,027,547 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004955463 285,228 306,077 RGD:9068941
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004955425 1,032,446 1,224,300 RGD:9068941
G Dhx36 DEAH-box helicase 36 JBrowse link NW_004955448 5,634,072 5,676,272 RGD:9068941
G Nanos1 nanos C2HC-type zinc finger 1 JBrowse link NW_004955431 23,538,224 23,540,039 RGD:9068941
G Nanos2 nanos C2HC-type zinc finger 2 JBrowse link NW_004955574 333,007 333,529 RGD:9068941
G Nanos3 nanos C2HC-type zinc finger 3 JBrowse link NW_004955415 32,648,455 32,651,909 RGD:9068941
G Pabpc1 poly(A) binding protein cytoplasmic 1 JBrowse link NW_004955417 15,872,906 15,885,246 RGD:9068941
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link NW_004955413 25,820,428 26,060,681 RGD:9068941
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link NW_004955506 4,440,555 4,579,642 RGD:9068941
G Tob1 transducer of ERBB2, 1 JBrowse link NW_004955451 10,950,270 10,963,183 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004955468 152,744 155,140 RGD:9068941
G Zfp36l1 ZFP36 ring finger protein like 1 JBrowse link NW_004955466 1,541,367 1,546,617 RGD:9068941
G Zfp36l2 ZFP36 ring finger protein like 2 JBrowse link NW_004955441 10,467,608 10,469,885 RGD:9068941
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004955461 14,194,268 14,260,949 RGD:9068941
G Btg2 BTG anti-proliferation factor 2 JBrowse link NW_004955406 39,303,221 39,307,308 RGD:9068941
G Cnot1 CCR4-NOT transcription complex subunit 1 JBrowse link NW_004955433 15,938,791 16,027,547 RGD:9068941
G Cnot7 CCR4-NOT transcription complex subunit 7 JBrowse link NW_004955463 285,228 306,077 RGD:9068941
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link NW_004955425 1,032,446 1,224,300 RGD:9068941
G Pabpc1 poly(A) binding protein cytoplasmic 1 JBrowse link NW_004955417 15,872,906 15,885,246 RGD:9068941
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link NW_004955413 25,820,428 26,060,681 RGD:9068941
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link NW_004955506 4,440,555 4,579,642 RGD:9068941
G Tob1 transducer of ERBB2, 1 JBrowse link NW_004955451 10,950,270 10,963,183 RGD:9068941
G Zfp36 ZFP36 ring finger protein JBrowse link NW_004955468 152,744 155,140 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    metabolic process 7569
      catabolic process 1621
        positive regulation of catabolic process 409
          positive regulation of cellular catabolic process 349
            positive regulation of mRNA catabolic process 47
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 31
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 16
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 11825
    metabolic process 7569
      cellular metabolic process 6989
        cellular aromatic compound metabolic process 3713
          nucleobase-containing compound metabolic process 3544
            nucleic acid metabolic process 3258
              RNA metabolic process 2891
                RNA catabolic process 193
                  mRNA catabolic process 162
                    regulation of mRNA catabolic process 107
                      positive regulation of mRNA catabolic process 47
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 31
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 16
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.