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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mRNA catabolic process
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Accession:GO:0061014 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
Synonyms:related_synonym: positive regulation of mRNA decay


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positive regulation of mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 38,793,212 38,902,686 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 16,439,014 16,459,636 RGD:9068941
G CNOT8 CCR4-NOT transcription complex subunit 8 JBrowse link 5 150,262,907 150,280,215 RGD:9068941
G GTPBP1 GTP binding protein 1 JBrowse link 22 19,621,159 19,648,848 RGD:9068941
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 1 22,501,816 22,536,050 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 19 5,433,989 5,445,721 RGD:9068941
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 1 115,327,051 115,353,483 RGD:9068941
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 2A 55,792,412 55,848,242 RGD:9068941
G PRR5L proline rich 5 like JBrowse link 11 36,269,291 36,438,954 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 149,454,748 149,539,566 RGD:9068941
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 19 18,269,878 18,306,199 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 36,743,341 36,753,261 RGD:9068941
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 7 131,002,580 131,068,513 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 19 36,505,056 36,507,693 RGD:9068941
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 88,794,186 89,038,808 RGD:9068941
G DHX36 DEAH-box helicase 36 JBrowse link 3 151,331,468 151,382,406 RGD:9068941
G DND1 DND microRNA-mediated repression inhibitor 1 JBrowse link 5 136,035,464 136,038,524 RGD:9068941
G HNRNPD heterogeneous nuclear ribonucleoprotein D JBrowse link 4 41,825,518 41,846,166 RGD:9068941
G KHSRP KH-type splicing regulatory protein JBrowse link 19 5,433,989 5,445,721 RGD:9068941
G MOV10 Mov10 RISC complex RNA helicase JBrowse link 1 115,327,051 115,353,483 RGD:9068941
G PLEKHN1 pleckstrin homology domain containing N1 RGD:9068941
G QKI QKI, KH domain containing RNA binding JBrowse link 6 161,361,413 161,523,414 RGD:9068941
G RBM24 RNA binding motif protein 24 JBrowse link 6 17,140,450 17,153,035 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 149,454,748 149,539,566 RGD:9068941
G TARDBP TAR DNA binding protein JBrowse link 1 9,775,084 9,786,710 RGD:9068941
G TRIM71 tripartite motif containing 71 JBrowse link 3 32,745,217 32,824,985 RGD:9068941
G UPF1 UPF1 RNA helicase and ATPase JBrowse link 19 18,269,878 18,306,199 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 36,743,341 36,753,261 RGD:9068941
G ZC3H12D zinc finger CCCH-type containing 12D JBrowse link 6 147,266,039 147,304,289 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 19 36,505,056 36,507,693 RGD:9068941
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 14 49,372,058 49,379,116 RGD:9068941
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 2A 43,311,744 43,315,928 RGD:9068941
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNOT6L CCR4-NOT transcription complex subunit 6 like JBrowse link 4 46,374,255 46,482,552 RGD:9068941
G FTO FTO alpha-ketoglutarate dependent dioxygenase JBrowse link 16 33,939,300 34,343,419 RGD:9068941
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 2B 119,929,004 120,090,367 RGD:9068941
G HNRNPR heterogeneous nuclear ribonucleoprotein R JBrowse link 1 22,501,816 22,536,050 RGD:9068941
G METTL14 methyltransferase like 14 JBrowse link 4 110,879,137 110,905,131 RGD:9068941
G METTL16 methyltransferase like 16 JBrowse link 17 2,407,331 2,500,418 RGD:9068941
G METTL3 methyltransferase like 3 JBrowse link 14 2,315,868 2,329,460 RGD:9068941
G PUM1 pumilio RNA binding family member 1 JBrowse link 1 30,205,584 30,341,979 RGD:9068941
G RBM24 RNA binding motif protein 24 JBrowse link 6 17,140,450 17,153,035 RGD:9068941
G RIDA reactive intermediate imine deaminase A homolog JBrowse link 8 94,739,120 94,753,934 RGD:9068941
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 18 14,192,293 14,352,357 RGD:9068941
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2A 11,167,353 11,331,339 RGD:9068941
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 JBrowse link 1 28,007,592 28,041,179 RGD:9068941
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 JBrowse link 8 59,701,341 59,742,865 RGD:9068941
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL16 methyltransferase like 16 JBrowse link 17 2,407,331 2,500,418 RGD:9068941
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFP36 ZFP36 ring finger protein JBrowse link 19 36,505,056 36,507,693 RGD:9068941
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 137,192,037 137,308,059 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 38,793,212 38,902,686 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 16,439,014 16,459,636 RGD:9068941
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 88,794,186 89,038,808 RGD:9068941
G DHX36 DEAH-box helicase 36 JBrowse link 3 151,331,468 151,382,406 RGD:9068941
G NANOS1 nanos C2HC-type zinc finger 1 JBrowse link 10 115,603,040 115,607,245 RGD:9068941
G NANOS2 nanos C2HC-type zinc finger 2 JBrowse link 19 42,922,655 42,924,679 RGD:9068941
G NANOS3 nanos C2HC-type zinc finger 3 JBrowse link 19 13,427,661 13,443,218 RGD:9068941
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 8 97,346,433 97,365,628 RGD:9068941
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 22 21,149,646 21,240,006 RGD:9068941
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 17 72,035,737 72,185,489 RGD:9068941
G TOB1 transducer of ERBB2, 1 JBrowse link 17 44,953,343 44,957,465 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 19 36,505,056 36,507,693 RGD:9068941
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 14 49,372,058 49,379,116 RGD:9068941
G ZFP36L2 ZFP36 ring finger protein like 2 JBrowse link 2A 43,311,744 43,315,928 RGD:9068941
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 137,192,037 137,308,059 RGD:9068941
G BTG2 BTG anti-proliferation factor 2 JBrowse link 1 178,907,317 178,911,410 RGD:9068941
G CNOT1 CCR4-NOT transcription complex subunit 1 JBrowse link 16 38,793,212 38,902,686 RGD:9068941
G CNOT7 CCR4-NOT transcription complex subunit 7 JBrowse link 8 16,439,014 16,459,636 RGD:9068941
G CPEB3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 10 88,794,186 89,038,808 RGD:9068941
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 8 97,346,433 97,365,628 RGD:9068941
G TNRC6B trinucleotide repeat containing adaptor 6B JBrowse link 22 21,149,646 21,240,006 RGD:9068941
G TNRC6C trinucleotide repeat containing adaptor 6C JBrowse link 17 72,035,737 72,185,489 RGD:9068941
G TOB1 transducer of ERBB2, 1 JBrowse link 17 44,953,343 44,957,465 RGD:9068941
G ZFP36 ZFP36 ring finger protein JBrowse link 19 36,505,056 36,507,693 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    metabolic process 7937
      catabolic process 1686
        positive regulation of catabolic process 416
          positive regulation of cellular catabolic process 355
            positive regulation of mRNA catabolic process 47
              induction by virus of catabolism of host mRNA + 0
              mRNA destabilization + 31
              negative regulation of 3'-UTR-mediated mRNA stabilization 1
              positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
              positive regulation of mitochondrial mRNA catabolic process 0
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 16
              positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
Path 2
Term Annotations click to browse term
  biological_process 12490
    metabolic process 7937
      cellular metabolic process 7295
        cellular aromatic compound metabolic process 3854
          nucleobase-containing compound metabolic process 3680
            nucleic acid metabolic process 3378
              RNA metabolic process 3000
                RNA catabolic process 197
                  mRNA catabolic process 164
                    regulation of mRNA catabolic process 108
                      positive regulation of mRNA catabolic process 47
                        induction by virus of catabolism of host mRNA + 0
                        mRNA destabilization + 31
                        negative regulation of 3'-UTR-mediated mRNA stabilization 1
                        positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA 1
                        positive regulation of mitochondrial mRNA catabolic process 0
                        positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + 16
                        positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.