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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of dendritic spine development
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Accession:GO:0061000 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


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negative regulation of dendritic spine development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) RGD PMID:24328732 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5464048|PMID:23050017)
Ensembl
RGD
PMID:23050017 GO_REF:0000107 MGI:5464048 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754
JBrowse link
G Fstl4 follistatin-like 4 acts_upstream_of_or_within ISO (MGI:5566541|PMID:24573299) RGD PMID:24573299 MGI:5566541 NCBI chr10:36,911,228...37,338,665
Ensembl chr10:36,911,420...37,338,588
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A involved_in IDA PMID:24297929 UniProt PMID:24297929 RGD:42721994 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:23485013 RGD:9590265 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:22548193 RGD:10413901 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5431284|PMID:22519304)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22519304 GO_REF:0000024 GO_REF:0000107 MGI:5431284 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
negative regulation of dendritic spine morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnm3 dynamin 3 IDA RGD PMID:17880892 RGD:8553820 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IMP
IDA
RGD PMID:20531346 PMID:20531346 RGD:11251757, RGD:11251757 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Efna1 ephrin A1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3696283|PMID:17143272)
UniProt
RGD
PMID:17143272 GO_REF:0000024 MGI:3696283 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISS
ISO
GO_REF:0000024
(MGI:3696283|PMID:17143272)
UniProt
RGD
PMID:17143272 GO_REF:0000024 MGI:3696283 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
JBrowse link
G Nlgn1 neuroligin 1 involved_in ISO
ISS
UniProtKB:Q99K10 (PMID:23143522)
(MGI:5493186|PMID:23143522)
GO_REF:0000024
RGD
BHF-UCL
PMID:23143522 GO_REF:0000024 MGI:5493186 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISO (MGI:5286761|PMID:21808020) RGD PMID:21808020 MGI:5286761 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3629385|PMID:16675393) RGD PMID:16675393 MGI:3629385 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ube3a ubiquitin protein ligase E3A IMP RGD PMID:25867122 RGD:11079590 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      negative regulation of developmental process 1023
        negative regulation of dendritic spine development 17
          negative regulation of dendritic spine morphogenesis 8
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      anatomical structure development 6196
        multicellular organism development 5633
          system development 5301
            nervous system development 2733
              neurogenesis 1953
                generation of neurons 1795
                  neuron differentiation 1624
                    neuron development 1335
                      neuron projection development 1169
                        dendrite development 321
                          dendritic spine development 131
                            regulation of dendritic spine development 85
                              negative regulation of dendritic spine development 17
                                negative regulation of dendritic spine morphogenesis 8
paths to the root