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ONTOLOGY REPORT - ANNOTATIONS


Term:endocrine hormone secretion
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Accession:GO:0060986 term browser browse the term
Definition:The regulated release of a hormone into the circulatory system.


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aldosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (MGI:3618038|PMID:9557921) MGI PMID:9557921 MGI:3618038 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:1566502 RGD:6903876 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
corticosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (MGI:3721200|PMID:17660684) MGI PMID:17660684 MGI:3721200 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G Selenom selenoprotein M acts_upstream_of_or_within ISO (MGI:5527224|PMID:23880772) MGI PMID:23880772 MGI:5527224 NCBI chrNW_004936755:285,836...288,501 JBrowse link
corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) acts_upstream_of_or_within ISO (MGI:3805139|PMID:18511498) MGI PMID:18511498 MGI:3805139 NCBI chrNW_004936478:7,146,997...7,160,369 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISO (MGI:1267130|PMID:9655498) UniProt PMID:9655498 MGI:1267130 NCBI chrNW_004936541:2,288,847...2,333,129 JBrowse link
cortisol secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin involved_in ISO (PMID:15201064) AgBase PMID:15201064 NCBI chrNW_004936493:7,060,747...7,065,276 JBrowse link
follicle-stimulating hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO (MGI:1316794|PMID:12114718) MGI PMID:12114718 MGI:1316794 NCBI chrNW_004936510:4,679,349...4,696,511 JBrowse link
G Tbx3 T-box transcription factor 3 involved_in ISO (PMID:12116211) UniProt PMID:12116211 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
gonadotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Niban2 niban apoptosis regulator 2 involved_in ISO (PMID:18628527)
(PMID:14602737)
UniProt PMID:14602737 PMID:18628527 NCBI chrNW_004936487:15,221,207...15,269,515 JBrowse link
luteinizing hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO (MGI:1316794|PMID:12114718) MGI PMID:12114718 MGI:1316794 NCBI chrNW_004936510:4,679,349...4,696,511 JBrowse link
G Tbx3 T-box transcription factor 3 involved_in ISO (PMID:12116211) UniProt PMID:12116211 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
G Tmf1 TATA element modulatory factor 1 acts_upstream_of_or_within ISO (MGI:5469555|PMID:23000399) MGI PMID:23000399 MGI:5469555 NCBI chrNW_004936603:1,577,519...1,602,022 JBrowse link
negative regulation of adiponectin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta involved_in ISO (MGI:3828398|PMID:16865359) BHF-UCL PMID:16865359 MGI:3828398 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 involved_in ISO (PMID:24040321) CACAO PMID:24040321 NCBI chrNW_004936710:1,306,430...1,338,502 JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 involved_in ISO (PMID:24040321) CACAO PMID:24040321 NCBI chrNW_004936501:470,307...535,958 JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:24040321) CACAO PMID:24040321 NCBI chrNW_004936491:16,883,972...16,919,539 JBrowse link
negative regulation of corticosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrg1 neuregulin 1 ISO RGD PMID:21092742 RGD:10449008 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Tspo translocator protein ISO RGD PMID:29074640 RGD:150429771 NCBI chrNW_004936718:992,301...995,172 JBrowse link
negative regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101956765 corticotropin releasing hormone binding protein involved_in ISO (PMID:1846945) UniProt PMID:1846945 RGD:69816 NCBI chrNW_004936549:64,866...78,272 JBrowse link
negative regulation of cortisol secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 acts_upstream_of_or_within ISO (MGI:3513751|PMID:15520383) MGI PMID:15520383 MGI:3513751 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
negative regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19193717 RGD:2317015 NCBI chrNW_004936478:6,901,098...6,947,719 JBrowse link
G Inha inhibin subunit alpha ISO immature male rats
female rats during diestrus-1
RGD PMID:2500324 PMID:8015360 RGD:2290442 RGD:2290444 NCBI chrNW_004936569:1,949,747...1,954,179 JBrowse link
G Inhbb inhibin subunit beta B involved_in ISO (PMID:3122219) UniProt PMID:3122219 NCBI chrNW_004936469:50,186,036...50,191,455 JBrowse link
G Ucn2 urocortin 2 ISO RGD PMID:19193717 RGD:2317015 NCBI chrNW_004936529:347,411...348,040 JBrowse link
negative regulation of glucocorticoid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (MGI:5495865|PMID:23531614) UniProt PMID:23531614 MGI:5495865 NCBI chrNW_004936492:7,929,138...7,994,797 JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISO (MGI:5495865|PMID:23531614) UniProt PMID:23531614 MGI:5495865 NCBI chrNW_004936562:3,133,849...3,168,472 JBrowse link
negative regulation of gonadotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein alpha 1 involved_in ISO (PMID:30599359) ARUK-UCL PMID:30599359 NCBI chrNW_004936658:3,920,043...3,932,987 JBrowse link
G Npvf neuropeptide VF precursor involved_in ISO (PMID:20027225) UniProt PMID:20027225 NCBI chrNW_004936478:2,107,835...2,111,188 JBrowse link
negative regulation of luteinizing hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO RGD PMID:20663987 RGD:5508201 NCBI chrNW_004936496:7,759,656...7,761,555 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19193717 RGD:2317015 NCBI chrNW_004936478:6,901,098...6,947,719 JBrowse link
G Oprk1 opioid receptor kappa 1 ISO RGD PMID:23391862 RGD:9831393 NCBI chrNW_004936496:280,593...305,900 JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:9376629 RGD:5147487 NCBI chrNW_004936521:9,053,179...9,065,790 JBrowse link
G Ucn2 urocortin 2 ISO RGD PMID:19193717 RGD:2317015 NCBI chrNW_004936529:347,411...348,040 JBrowse link
negative regulation of progesterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:18703674) AgBase PMID:18703674 NCBI chrNW_004936595:919,807...935,367 JBrowse link
parathyroid hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4460059|PMID:20484821) MGI PMID:20484821 MGI:4460059 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Trpv6 transient receptor potential cation channel subfamily V member 6 acts_upstream_of_or_within ISO (MGI:3777868|PMID:17129178) MGI PMID:17129178 MGI:3777868 NCBI chrNW_004936527:345,237...359,877 JBrowse link
positive regulation of adiponectin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf3 C1q and TNF related 3 involved_in ISO (PMID:18421280)
(MGI:5442507|PMID:17299102)
UniProt PMID:17299102 PMID:18421280 MGI:5442507 NCBI chrNW_004936518:7,039,590...7,060,463 JBrowse link
G LOC101978400 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chrNW_004936558:1,899,313...1,901,409 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO PMID:29695452 BHF-UCL PMID:29695452 RGD:150521636 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
positive regulation of aldosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:22538126 RGD:7242193 NCBI chrNW_004936534:4,707,658...4,871,865 JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:18171693) UniProt PMID:18171693 NCBI chrNW_004936594:3,338,863...3,358,137 JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
positive regulation of androgen secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:19886863) UniProt PMID:19886863 NCBI chrNW_004936555:7,087,677...7,091,334 JBrowse link
positive regulation of corticosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO RGD PMID:12606499 PMID:20663987 RGD:5508201 RGD:704397 NCBI chrNW_004936496:7,759,656...7,761,555 JBrowse link
G Tac1 tachykinin precursor 1 ISO RGD PMID:8391371 RGD:5147624 NCBI chrNW_004936585:2,932,783...2,941,141 JBrowse link
positive regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin ISO RGD PMID:16896162 RGD:1626228 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Crh corticotropin releasing hormone involved_in ISO (PMID:11329063) RGD
UniProt
PMID:7477349 PMID:11329063 PMID:20663987 RGD:5508201 RGD:70047 NCBI chrNW_004936496:7,759,656...7,761,555 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:12566947) BHF-UCL PMID:12566947 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Lif LIF interleukin 6 family cytokine ISO RGD PMID:20160138 RGD:2326054 NCBI chrNW_004936904:410,043...413,256 JBrowse link
G Pex5l peroxisomal biogenesis factor 5 like ISO RGD PMID:11278749 RGD:737646 NCBI chrNW_004936566:3,195,110...3,411,037 JBrowse link
G Rab8b RAB8B, member RAS oncogene family ISO RGD PMID:11278749 RGD:737646 NCBI chrNW_004936471:23,768,460...23,832,072 JBrowse link
G Ucn urocortin involved_in ISO (PMID:11329063) RGD
UniProt
PMID:7477349 PMID:11329063 RGD:70047 NCBI chrNW_004936493:5,258,574...5,260,692 JBrowse link
positive regulation of cortisol secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone involved_in ISO (PMID:18329818) BHF-UCL PMID:18329818 NCBI chrNW_004936496:7,759,656...7,761,555 JBrowse link
G Gal galanin and GMAP prepropeptide involved_in ISO (PMID:17982695) UniProt PMID:17982695 NCBI chrNW_004936599:1,563,270...1,567,618 JBrowse link
G Galr1 galanin receptor 1 involved_in ISO (PMID:17982695) UniProt PMID:17982695 NCBI chrNW_004936616:2,007,339...2,020,737 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:12566947), (PMID:18329818) BHF-UCL PMID:12566947 PMID:18329818 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
positive regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A ISO RGD PMID:11861519 RGD:2325238 NCBI chrNW_004936469:29,195,329...29,273,237 JBrowse link
G Foxl2 forkhead box L2 acts_upstream_of_or_within ISO (MGI:5604269|PMID:24739304) MGI PMID:24739304 MGI:5604269 NCBI chrNW_004936540:1,136,403...1,137,984 JBrowse link
G Inhbb inhibin subunit beta B involved_in ISO (PMID:3122219) UniProt PMID:3122219 NCBI chrNW_004936469:50,186,036...50,191,455 JBrowse link
G LOC101968976 leptin ISO RGD PMID:19112389 RGD:5128709 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G Smad4 SMAD family member 4 acts_upstream_of_or_within ISO (MGI:5604269|PMID:24739304) MGI PMID:24739304 MGI:5604269 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
positive regulation of luteinizing hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxl2 forkhead box L2 acts_upstream_of_or_within ISO (MGI:5604269|PMID:24739304) MGI PMID:24739304 MGI:5604269 NCBI chrNW_004936540:1,136,403...1,137,984 JBrowse link
G Kiss1 KiSS-1 metastasis suppressor ISO RGD PMID:17213691 PMID:17532794 RGD:2292143 RGD:2292159 NCBI chrNW_004936567:584,443...595,045 JBrowse link
G LOC101968976 leptin ISO RGD PMID:19112389 RGD:5128709 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G Smad4 SMAD family member 4 acts_upstream_of_or_within ISO (MGI:5604269|PMID:24739304) MGI PMID:24739304 MGI:5604269 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
positive regulation of parathyroid hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:5548021|PMID:24259513) MGI PMID:24259513 MGI:5548021 NCBI chrNW_004936710:1,760,365...1,815,269 JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO (MGI:5548021|PMID:24259513) MGI PMID:24259513 MGI:5548021 NCBI chrNW_004936597:1,388,394...1,397,731 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO RGD PMID:32231239 RGD:32716373 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Vdr vitamin D receptor ISO RGD PMID:32231239 RGD:32716373 NCBI chrNW_004936512:5,741,836...5,800,999 JBrowse link
positive regulation of progesterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfn2 mitofusin 2 ISO RGD PMID:25120590 RGD:13204819 NCBI chrNW_004936474:767,754...795,258 JBrowse link
G Retn resistin ISO RGD PMID:21239528 RGD:7207233 NCBI chrNW_004936588:4,705,295...4,706,653 JBrowse link
progesterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within ISO (MGI:3692134|PMID:16093361) MGI PMID:16093361 MGI:3692134 NCBI chrNW_004936498:14,657,641...14,666,853 JBrowse link
G Inhba inhibin subunit beta A involved_in ISO (PMID:10932194) UniProt PMID:10932194 NCBI chrNW_004936478:16,878,725...16,884,065 JBrowse link
regulation of corticosterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISO (MGI:1267130|PMID:9655498) UniProt PMID:9655498 MGI:1267130 NCBI chrNW_004936541:2,288,847...2,333,129 JBrowse link
G Pomc proopiomelanocortin acts_upstream_of_or_within ISO (MGI:5302462|PMID:21184805) MGI PMID:21184805 MGI:5302462 NCBI chrNW_004936493:7,060,747...7,065,276 JBrowse link
regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101956765 corticotropin releasing hormone binding protein involved_in ISO (PMID:13150566) UniProt PMID:13150566 NCBI chrNW_004936549:64,866...78,272 JBrowse link
regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inhba inhibin subunit beta A involved_in ISO (PMID:10932194) UniProt PMID:10932194 NCBI chrNW_004936478:16,878,725...16,884,065 JBrowse link
regulation of parathyroid hormone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101971027 neuroendocrine secretory protein 55 acts_upstream_of_or_within ISO (MGI:3574969|PMID:15811946) MGI PMID:15811946 MGI:3574969 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
regulation of progesterone secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:12050262)
(PMID:20660033)
UniProt PMID:12050262 PMID:20660033 NCBI chrNW_004936647:2,351,604...2,357,043 JBrowse link
renin-angiotensin regulation of aldosterone production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (MGI:1332965|PMID:10076178), (MGI:2385818|PMID:9852267) RGD
MGI
PMID:9852267 PMID:10076178 PMID:21318332 MGI:1332965 MGI:2385818 RGD:5129178 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:21318332 RGD:5129178 NCBI chrNW_004936519:6,831,096...6,873,977 JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:21318332 RGD:5129178 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
G Ren renin acts_upstream_of_or_within ISO (MGI:3848759|PMID:19293336) MGI PMID:19293336 MGI:3848759 NCBI chrNW_004936567:598,044...607,628 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12298
    multicellular organismal process 6390
      system process 1652
        endocrine process 101
          endocrine hormone secretion 66
            adiponectin secretion + 7
            corticotropin secretion + 10
            gonadotropin secretion + 19
            inhibin secretion + 0
            juvenile hormone secretion + 0
            parathyroid hormone secretion + 7
            steroid hormone secretion + 28
Path 2
Term Annotations click to browse term
  biological_process 12298
    localization 4949
      establishment of localization 3527
        transport 3366
          secretion 975
            secretion by cell 826
              signal release 560
                hormone secretion 368
                  endocrine hormone secretion 66
                    adiponectin secretion + 7
                    corticotropin secretion + 10
                    gonadotropin secretion + 19
                    inhibin secretion + 0
                    juvenile hormone secretion + 0
                    parathyroid hormone secretion + 7
                    steroid hormone secretion + 28
paths to the root