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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of gene silencing
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Accession:GO:0060969 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.


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negative regulation of chromatin silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad2 ATPase family, AAA domain containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atad2b ATPase family, AAA domain containing 2B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:28,998,080...29,066,850
Ensembl chr 6:29,012,007...29,163,134
JBrowse link
G H1f0 H1.0 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H1f1 H1.1 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,614,101...43,614,844
Ensembl chr17:43,614,101...43,614,844
JBrowse link
G H1f10 H1.10 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:119,889,016...119,892,661
Ensembl chr 4:119,889,371...119,889,949
JBrowse link
G H1f2 H1.2 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H1f4 H1.4 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H1f5 H1.5 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H1f6 H1.6 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,675,190...43,675,934
Ensembl chr17:43,675,190...43,675,934
JBrowse link
G H1f8 H1.8 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:147,844,658...147,849,779
Ensembl chr 4:147,844,658...147,849,779
JBrowse link
G H4f3 H1.3 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,775,691...82,776,487
Ensembl chr10:82,775,691...82,776,487
JBrowse link
negative regulation of gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in ISO
IBA
(PMID:18155131)
PMID:21873635
RGD PMID:18155131, PMID:21873635 RGD:13792537 NCBI chr18:29,608,588...29,611,212
Ensembl chr18:29,608,588...29,611,212
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in ISO
ISS
RNAcentral:URS000024463E_9606 (PMID:26595526), (PMID:27089893)
GO_REF:0000024
RGD
UniProt
PMID:26595526 PMID:27089893 GO_REF:0000024 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19409607) RGD PMID:19409607 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:141,132,106...141,136,700
Ensembl chr 7:141,132,133...141,136,700
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 acts_upstream_of ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 involved_in ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20388878)
Ensembl
RGD
PMID:20388878 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:5562625 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343 PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 involved_in ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:2,968,428...2,972,521
Ensembl chr 7:2,968,435...2,972,521
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(PMID:22055188)
UniProt
RGD
PMID:22055188 GO_REF:0000024 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tert telomerase reverse transcriptase involved_in ISO (PMID:19701182) RGD PMID:19701182 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
negative regulation of RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3573853|PMID:15556947)
Ensembl
RGD
PMID:15556947 GO_REF:0000107 MGI:3573853 NCBI chr 2:189,045,551...189,085,448
Ensembl chr 2:189,062,443...189,083,236
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    negative regulation of biological process 5614
      negative regulation of cellular process 5102
        negative regulation of gene silencing 33
          negative regulation of chromatin silencing + 12
          negative regulation of gene silencing by RNA + 21
          negative regulation of posttranscriptional gene silencing + 21
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological process 12857
        regulation of metabolic process 6808
          regulation of macromolecule metabolic process 6320
            negative regulation of macromolecule metabolic process 2975
              negative regulation of gene expression 1119
                gene silencing 250
                  regulation of gene silencing 75
                    negative regulation of gene silencing 33
                      negative regulation of chromatin silencing + 12
                      negative regulation of gene silencing by RNA + 21
                      negative regulation of posttranscriptional gene silencing + 21
paths to the root