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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of gene silencing by RNA
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Accession:GO:0060966 term browser browse the term
Definition:Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


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negative regulation of miRNA maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:23674172 RGD:150540303 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:20388878) BHF-UCL PMID:20388878 NCBI chr12:59,256,868...59,392,564 JBrowse link
G NCOR2 nuclear receptor corepressor 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:28,642,774...28,819,404
Ensembl chr14:28,624,702...28,819,404 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 8:119,429,181...119,754,615
Ensembl chr 8:119,428,743...119,754,650 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:22269326) BHF-UCL PMID:22269326 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31124343), (PMID:31824476) Ensembl
Ensembl
ARUK-UCL		 PMID:31124343 PMID:31824476 GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5013521|PMID:21522133) Ensembl
Ensembl
MGI		 PMID:21522133 GO_REF:0000107 MGI:5013521 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819 		JBrowse link
G ZC3H10 zinc finger CCCH-type containing 10 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:21,506,510...21,513,972
Ensembl chr 5:21,508,218...21,514,626 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,195 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5013521|PMID:21522133) MGI
Ensembl
Ensembl		 PMID:21522133 GO_REF:0000107 MGI:5013521 NCBI chr 6:96,008,307...96,057,131
Ensembl chr 6:96,008,455...96,062,951 		JBrowse link
negative regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DND1 DND microRNA-mediated repression inhibitor 1 involved_in ISS
IBA
IEA		 (PMID:21873635) AgBase
GO_Central
Ensembl
AgBase
GO_Central		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:142,384,526...142,387,407
Ensembl chr 2:142,384,532...142,387,199 		JBrowse link
G ELAVL1 ELAV like RNA binding protein 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:71,207,141...71,245,863
Ensembl chr 2:71,207,124...71,248,916 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (PMID:19409607) UniProt PMID:19409607 NCBI chr 7:23,564,654...23,570,691 JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28522568) BHF-UCL PMID:28522568 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:22269326) BHF-UCL PMID:22269326 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048 		JBrowse link
negative regulation of post-transcriptional gene silencing by RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3573853|PMID:15556947) Ensembl
Ensembl
MGI		 PMID:15556947 GO_REF:0000107 MGI:3573853 NCBI chr 4:95,154,230...95,197,308
Ensembl chr 4:95,154,358...95,197,305 		JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCDIN3D BCDIN3 domain containing RNA methyltransferase involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 5:15,755,307...15,761,645
Ensembl chr 5:15,751,312...15,761,537 		JBrowse link
G LIN28B lin-28 homolog B involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:71,173,291...71,296,131
Ensembl chr 1:71,166,786...71,296,861 		JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6 interleukin 6 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:31507089) ARUK-UCL
Ensembl
Ensembl		 PMID:31507089 GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263 		JBrowse link
G LIN28B lin-28 homolog B involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:71,173,291...71,296,131
Ensembl chr 1:71,166,786...71,296,861 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:24636259 RGD:12789709 NCBI chr  X:124,735,523...124,789,063
Ensembl chr  X:124,735,656...124,789,110 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993 		JBrowse link
negative regulation of siRNA production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERT telomerase reverse transcriptase involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421 		JBrowse link
positive regulation of miRNA maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,134...183,792,417 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:14,571,712...14,580,740
Ensembl chr12:14,571,310...14,601,576 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,478,882 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:27252421) ARUK-UCL
Ensembl
Ensembl		 PMID:27252421 GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263 		JBrowse link
G LIN28A lin-28 homolog A involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:83,806,178...83,818,550
Ensembl chr 6:83,806,122...83,818,631 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,626,739...74,651,352
Ensembl chr 2:74,626,658...74,651,348 		JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,538 		JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 acts_upstream_of_or_within ISO (MGI:5574156|PMID:24349493) MGI PMID:24349493 MGI:5574156 NCBI chr 2:100,447,661...100,457,510
Ensembl chr 2:100,447,847...100,457,904 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,236...1,880,699 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819 		JBrowse link
positive regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 7:76,063,009...76,072,884
Ensembl chr 7:76,063,034...76,076,594 		JBrowse link
G DHX9 DExH-box helicase 9 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 9:124,141,929...124,183,838
Ensembl chr 9:124,093,667...124,185,352 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,229...120,399,835 		JBrowse link
G FXR1 FMR1 autosomal homolog 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr13:118,839,314...118,899,804
Ensembl chr13:118,839,338...118,900,138 		JBrowse link
G LIMD1 LIM domain containing 1 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr13:28,730,192...28,811,584
Ensembl chr13:28,730,260...28,811,616 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO PMID:24676391 BHF-UCL PMID:24676391 RGD:10400879 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,637...118,506,691 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:87,546,388...87,687,483
Ensembl chr 6:87,547,320...87,687,442 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:117,857,930...117,965,564
Ensembl chr 3:117,858,031...117,965,566 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993 		JBrowse link
G TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:129,441,209...129,467,150
Ensembl chr14:129,441,208...129,467,132 		JBrowse link
G TRIM71 tripartite motif containing 71 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4438512|PMID:19898466) Ensembl
Ensembl
MGI		 PMID:19898466 GO_REF:0000107 MGI:4438512 NCBI chr13:18,762,043...18,835,788
Ensembl chr13:18,761,445...18,830,563 		JBrowse link
G WTIP WT1 interacting protein involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 6:44,150,875...44,178,378
Ensembl chr 6:44,150,092...44,190,547 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:48,063,732...48,066,235
Ensembl chr 6:48,052,137...48,066,257 		JBrowse link
positive regulation of post-transcriptional gene silencing by RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XPO5 exportin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,530,725...38,569,570 		JBrowse link
positive regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRUB1 TruB pseudouridine synthase family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:125,262,142...125,328,604
Ensembl chr14:125,262,195...125,329,452 		JBrowse link
regulation of miRNA maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARBP2 TARBP2 subunit of RISC loading complex involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:6094668|PMID:27159388) InterPro
MGI
InterPro
Ensembl
Ensembl		 PMID:27159388 GO_REF:0000002 GO_REF:0000107 MGI:6094668 NCBI chr 5:18,718,588...18,723,843
Ensembl chr 5:18,718,158...18,723,843 		JBrowse link
regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,229...120,399,835 		JBrowse link
G LIN28A lin-28 homolog A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4438512|PMID:19898466) MGI
Ensembl		 PMID:19898466 GO_REF:0000107 MGI:4438512 NCBI chr 6:83,806,178...83,818,550
Ensembl chr 6:83,806,122...83,818,631 		JBrowse link
G MAEL maelstrom spermatogenic transposon silencer involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr 4:83,990,266...84,040,465
Ensembl chr 4:83,975,347...84,040,709 		JBrowse link
G MIRLET7A-1 microRNA let-7a-1 acts_upstream_of_or_within ISO (MGI:4438512|PMID:19898466) MGI PMID:19898466 MGI:4438512 NCBI chr 9:49,152,586...49,152,665
Ensembl chr 9:49,152,586...49,152,665 		JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO (MGI:5315650|PMID:22187428) MGI PMID:22187428 MGI:5315650 NCBI chr12:3,847,522...3,939,054
Ensembl chr12:3,846,428...3,935,391 		JBrowse link
G TRIM71 tripartite motif containing 71 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4438512|PMID:19898466) MGI
Ensembl		 PMID:19898466 GO_REF:0000107 MGI:4438512 NCBI chr13:18,762,043...18,835,788
Ensembl chr13:18,761,445...18,830,563 		JBrowse link
regulation of production of small RNA involved in gene silencing by RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:84,134,273...84,156,596
Ensembl chr15:84,133,679...84,156,508 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:18,718,588...18,723,843
Ensembl chr 5:18,718,158...18,723,843 		JBrowse link
regulation of siRNA production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:18,718,588...18,723,843
Ensembl chr 5:18,718,158...18,723,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17268
    regulation of biological process 12126
      regulation of metabolic process 6693
        regulation of macromolecule metabolic process 6182
          regulation of gene expression 4812
            regulation of gene silencing by RNA 50
              negative regulation of gene silencing by RNA + 21
              regulation of post-transcriptional gene silencing by RNA + 47
              regulation of production of small RNA involved in gene silencing by RNA + 29
Path 2
Term Annotations click to browse term
  biological_process 17268
    biological regulation 12761
      regulation of biological process 12126
        regulation of metabolic process 6693
          negative regulation of metabolic process 3271
            negative regulation of macromolecule metabolic process 3033
              negative regulation of gene expression 1294
                gene silencing by RNA 331
                  regulation of gene silencing by RNA 50
                    negative regulation of gene silencing by RNA + 21
                    regulation of post-transcriptional gene silencing by RNA + 47
                    regulation of production of small RNA involved in gene silencing by RNA + 29
paths to the root