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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of miRNA-mediated gene silencing
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Accession:GO:0060965 term browser browse the term
Definition:A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA).
Synonyms:exact_synonym: https://github.com/geneontology/go-ontology/issues/22888;   negative regulation of gene silencing by miRNA;   negative regulation of gene silencing by microRNA



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negative regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in ISO
IBA
(PMID:18155131)
PMID:21873635
RGD PMID:18155131 PMID:21873635 RGD:13792537 NCBI chr18:28,378,692...28,381,316
Ensembl chr18:28,378,692...28,381,316
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in ISO
ISS
RNAcentral:URS000024463E_9606 (PMID:26595526), (PMID:27089893)
GO_REF:0000024
RGD
UniProt
PMID:26595526 PMID:27089893 GO_REF:0000024 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19409607) RGD PMID:19409607 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
negative regulation of miRNA maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 involved_in ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:23674172 RGD:150540303 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:5562625 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343 PMID:31824476 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 involved_in ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:973,415...977,742
Ensembl chr 7:972,855...979,349
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(PMID:22055188)
UniProt
RGD
PMID:22055188 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 acts_upstream_of ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    negative regulation of biological process 5780
      negative regulation of post-transcriptional gene silencing 21
        negative regulation of post-transcriptional gene silencing by RNA 21
          negative regulation of miRNA-mediated gene silencing 20
            negative regulation of miRNA maturation + 16
Path 2
Term Annotations click to browse term
  biological_process 18872
    biological regulation 13378
      regulation of biological process 12642
        regulation of metabolic process 6786
          negative regulation of metabolic process 3314
            negative regulation of macromolecule metabolic process 3082
              negative regulation of gene expression 1268
                gene silencing by RNA 312
                  regulation of gene silencing by RNA 50
                    negative regulation of gene silencing by RNA 21
                      negative regulation of post-transcriptional gene silencing by RNA 21
                        negative regulation of miRNA-mediated gene silencing 20
                          negative regulation of miRNA maturation + 16
paths to the root