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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of miRNA-mediated gene silencing
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Accession:GO:0060964 term browser browse the term
Definition:A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs).
Synonyms:exact_synonym: regulation of gene silencing by miRNA;   regulation of gene silencing by microRNA

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regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lin28a lin-28 homolog A acts_upstream_of_or_within ISO (PMID:19898466) MGI PMID:19898466 NCBI chrNW_004936474:10,896,153...10,909,247 JBrowse link
G Mael maelstrom spermatogenic transposon silencer involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936481:18,903,153...18,928,195
Ensembl chrNW_004936481:18,903,153...18,928,195 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO (PMID:22187428) MGI PMID:22187428 NCBI chrNW_004936594:2,656,079...2,741,254
Ensembl chrNW_004936594:2,656,045...2,741,233 		JBrowse link
G Trim71 tripartite motif containing 71 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19898466) Ensembl
MGI		 PMID:19898466 GO_REF:0000107 NCBI chrNW_004936473:23,223,984...23,290,177
Ensembl chrNW_004936473:23,224,588...23,290,169 		JBrowse link
negative regulation of miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A ISO RGD PMID:23674172 RGD:150540303 NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21522133) Ensembl
MGI		 PMID:21522133 GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425 		JBrowse link
G Zc3h10 zinc finger CCCH-type containing 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:528,455...534,267
Ensembl chrNW_004936646:528,455...532,694 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21522133) Ensembl
MGI		 PMID:21522133 GO_REF:0000107 NCBI chrNW_004936474:22,035,059...22,077,846
Ensembl chrNW_004936474:22,034,801...22,077,986 		JBrowse link
negative regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936531:9,607,678...9,610,245
Ensembl chrNW_004936531:9,607,906...9,609,965 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,931,665...4,959,032
Ensembl chrNW_004936588:4,927,950...4,959,064 		JBrowse link
G Fmr1 Fragile X messenger ribonucleoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:1,290,038...1,327,850
Ensembl chrNW_004936513:1,289,558...1,327,856 		JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936512:7,516,324...7,521,063
Ensembl chrNW_004936512:7,514,348...7,521,017 		JBrowse link
G Lin28a lin-28 homolog A involved_in ISO (PMID:21247876) UniProt PMID:21247876 NCBI chrNW_004936474:10,896,153...10,909,247 JBrowse link
G Lin28b lin-28 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936564:1,646,469...1,768,879
Ensembl chrNW_004936564:1,663,068...1,768,283 		JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 acts_upstream_of ISO (PMID:31507089) ARUK-UCL PMID:31507089 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Lin28b lin-28 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936564:1,646,469...1,768,879
Ensembl chrNW_004936564:1,663,068...1,768,283 		JBrowse link
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:24636259 RGD:12789709 NCBI chrNW_004936809:902,938...967,771
Ensembl chrNW_004936809:911,764...966,839 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402 		JBrowse link
positive regulation of miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripk1 receptor interacting serine/threonine kinase 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:26020802) ARUK-UCL
Ensembl		 PMID:26020802 GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
positive regulation of miRNA-mediated gene silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ajuba ajuba LIM protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936722:1,331,568...1,341,854
Ensembl chrNW_004936722:1,331,566...1,341,863 		JBrowse link
G Fmr1 Fragile X messenger ribonucleoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:1,290,038...1,327,850
Ensembl chrNW_004936513:1,289,558...1,327,856 		JBrowse link
G Fxr1 FMR1 autosomal homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936566:2,354,301...2,425,140
Ensembl chrNW_004936566:2,354,441...2,425,176 		JBrowse link
G Limd1 LIM domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936695:260,586...314,521
Ensembl chrNW_004936695:259,209...314,535 		JBrowse link
G Pum1 pumilio RNA binding family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:14,243,325...14,363,461
Ensembl chrNW_004936474:14,243,296...14,363,500 		JBrowse link
G Pum2 pumilio RNA binding family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:11,067,318...11,154,133
Ensembl chrNW_004936493:11,067,202...11,155,377 		JBrowse link
G Tial1 TIA1 cytotoxic granule associated RNA binding protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:8,925,819...8,947,872
Ensembl chrNW_004936486:8,924,738...8,947,877 		JBrowse link
G Trim71 tripartite motif containing 71 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19898466) Ensembl
MGI		 PMID:19898466 GO_REF:0000107 NCBI chrNW_004936473:23,223,984...23,290,177
Ensembl chrNW_004936473:23,224,588...23,290,169 		JBrowse link
G Wtip WT1 interacting protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936570:1,469,181...1,494,574
Ensembl chrNW_004936570:1,470,368...1,494,580 		JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936661:2,251,148...2,253,527
Ensembl chrNW_004936661:2,250,665...2,253,787 		JBrowse link
positive regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgcr8 DGCR8 microprocessor complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:3,977,307...4,014,490
Ensembl chrNW_004936619:3,977,144...4,014,273
Ensembl chrNW_004936619:3,977,144...4,014,273 		JBrowse link
G Trub1 TruB pseudouridine synthase family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:5,135,379...5,166,858
Ensembl chrNW_004936486:5,135,398...5,164,901 		JBrowse link
positive regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:1,054,237...1,061,468
Ensembl chrNW_004936697:1,056,636...1,061,468 		JBrowse link
G Prpf6 pre-mRNA processing factor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936514:11,175,410...11,220,928
Ensembl chrNW_004936514:11,175,526...11,220,241 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    metabolic process 9527
      regulation of metabolic process 5499
        regulation of macromolecule metabolic process 4971
          regulation of macromolecule biosynthetic process 4233
            regulation of gene expression 4121
              regulation of post-transcriptional gene silencing 33
                regulation of post-transcriptional gene silencing by regulatory ncRNA 32
                  regulation of miRNA-mediated gene silencing 30
                    negative regulation of miRNA-mediated gene silencing + 13
                    positive regulation of miRNA-mediated gene silencing + 16
Path 2
Term Annotations click to browse term
  biological_process 15871
    biological regulation 11036
      regulation of biological process 10703
        regulation of metabolic process 5499
          regulation of cellular metabolic process 5071
            regulation of cellular biosynthetic process 4365
              regulation of macromolecule biosynthetic process 4233
                negative regulation of macromolecule biosynthetic process 2006
                  negative regulation of gene expression 1049
                    regulatory ncRNA-mediated gene silencing 108
                      regulatory ncRNA-mediated post-transcriptional gene silencing 49
                        regulation of post-transcriptional gene silencing by regulatory ncRNA 32
                          regulation of miRNA-mediated gene silencing 30
                            negative regulation of miRNA-mediated gene silencing + 13
                            positive regulation of miRNA-mediated gene silencing + 16
paths to the root