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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac vascular smooth muscle cell differentiation
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Accession:GO:0060947 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
Synonyms:exact_synonym: heart vascular smooth muscle cell differentiation


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cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755 		JBrowse link
G MIR143 microRNA mir-143 acts_upstream_of_or_within ISO (PMID:19816508) MGI PMID:19816508 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of_or_within ISO (PMID:19816508) MGI PMID:19816508 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G MYOCD myocardin involved_in ISO PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G SRF serum response factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15569937) Ensembl
MGI		 PMID:15569937 GO_REF:0000107 NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533 		JBrowse link
cardiac vascular smooth muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20619341) Ensembl
MGI		 PMID:20619341 GO_REF:0000107 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (MGI:4461879|PMID:18093989) BHF-UCL PMID:18093989 MGI:4461879 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr 1:64,630,656...64,646,546 JBrowse link
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      cellular developmental process 4594
        cell differentiation 4593
          cardiocyte differentiation 206
            cardiac vascular smooth muscle cell differentiation 10
              cardiac vascular smooth muscle cell development + 3
              cardiac vascular smooth muscle cell fate commitment + 0
              epicardium-derived cardiac vascular smooth muscle cell differentiation + 0
              negative regulation of cardiac vascular smooth muscle cell differentiation 1
              positive regulation of cardiac vascular smooth muscle cell differentiation 1
              regulation of cardiac vascular smooth muscle cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      anatomical structure development 6414
        multicellular organism development 5174
          system development 4502
            circulatory system development 1359
              vasculature development 887
                blood vessel development 843
                  coronary vasculature development 64
                    cardiac vascular smooth muscle cell differentiation 10
                      cardiac vascular smooth muscle cell development + 3
                      cardiac vascular smooth muscle cell fate commitment + 0
                      epicardium-derived cardiac vascular smooth muscle cell differentiation + 0
                      negative regulation of cardiac vascular smooth muscle cell differentiation 1
                      positive regulation of cardiac vascular smooth muscle cell differentiation 1
                      regulation of cardiac vascular smooth muscle cell differentiation + 2
paths to the root