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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chrNW_004936486:1,684,167...1,705,387 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chrNW_004936662:2,241,928...2,245,616 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    developmental process 5969
      anatomical structure morphogenesis 2643
        animal organ morphogenesis 1063
          heart morphogenesis 265
            cardiac epithelial to mesenchymal transition 37
              epithelial to mesenchymal transition involved in cardiac fibroblast development 2
Path 2
Term Annotations click to browse term
  biological_process 14973
    developmental process 5969
      anatomical structure development 5591
        multicellular organism development 4819
          system development 4403
            circulatory system development 1153
              heart development 655
                cardiocyte differentiation 181
                  cardiac cell development 108
                    cardiac fibroblast cell development 5
                      epicardium-derived cardiac fibroblast cell development 3
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 2
paths to the root