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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.



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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir21a microRNA 21a involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 3:37,694,096...37,698,748
Ensembl chr 3:37,694,096...37,698,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28746
    developmental process 7254
      anatomical structure morphogenesis 3062
        animal organ morphogenesis 1195
          heart morphogenesis 292
            cardiac epithelial to mesenchymal transition 38
              epithelial to mesenchymal transition involved in cardiac fibroblast development 3
Path 2
Term Annotations click to browse term
  biological_process 28746
    developmental process 7254
      anatomical structure development 6680
        multicellular organism development 5634
          system development 5123
            circulatory system development 1387
              heart development 732
                cardiocyte differentiation 217
                  cardiac cell development 125
                    cardiac fibroblast cell development 6
                      epicardium-derived cardiac fibroblast cell development 4
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 3
paths to the root