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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.



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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA 21 involved_in IDA (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G PDCD4 programmed cell death 4 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:123,396,795...123,403,760
Ensembl chr 4:123,396,795...123,403,760
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19656
    developmental process 7515
      anatomical structure morphogenesis 3222
        animal organ morphogenesis 1284
          heart morphogenesis 302
            cardiac epithelial to mesenchymal transition 39
              epithelial to mesenchymal transition involved in cardiac fibroblast development 3
Path 2
Term Annotations click to browse term
  biological_process 19656
    developmental process 7515
      anatomical structure development 6875
        multicellular organism development 5795
          system development 5324
            circulatory system development 1434
              heart development 760
                cardiocyte differentiation 216
                  cardiac cell development 127
                    cardiac fibroblast cell development 6
                      epicardium-derived cardiac fibroblast cell development 4
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 3
paths to the root