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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chrNW_004955485:530,642...553,508
Ensembl chrNW_004955485:529,860...553,601
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G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chrNW_004955428:17,451,703...17,455,695
Ensembl chrNW_004955428:17,451,703...17,455,695
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12182
    developmental process 5761
      anatomical structure morphogenesis 2561
        animal organ morphogenesis 1046
          heart morphogenesis 260
            cardiac epithelial to mesenchymal transition 37
              epithelial to mesenchymal transition involved in cardiac fibroblast development 2
Path 2
Term Annotations click to browse term
  biological_process 12182
    developmental process 5761
      anatomical structure development 5413
        multicellular organism development 4686
          system development 4283
            circulatory system development 1121
              heart development 644
                cardiocyte differentiation 179
                  cardiac cell development 109
                    cardiac fibroblast cell development 5
                      epicardium-derived cardiac fibroblast cell development 3
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 2
paths to the root