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ONTOLOGY REPORT - ANNOTATIONS
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Term:
epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:
GO:0060940
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Definition:
A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.
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Rat (3)
Mouse (3)
Human (3)
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Squirrel (2)
Pig (3)
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Genes (2)
epithelial to mesenchymal transition involved in cardiac fibroblast development
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Pdcd4
programmed cell death 4
involved_in
ISO
PMID:23441172
BHF-UCL
PMID:23441172
RGD:10400865
NCBI chrNW_004955485:530,642...553,508
Ensembl chrNW_004955485:529,860...553,601
G
Spry1
sprouty RTK signaling antagonist 1
involved_in
ISO
PMID:23441172
BHF-UCL
PMID:23441172
RGD:10400865
NCBI chrNW_004955428:17,451,703...17,455,695
Ensembl chrNW_004955428:17,451,703...17,455,695
Term paths to the root
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Path 1
Term
Annotations
biological_process
12182
developmental process
5761
anatomical structure morphogenesis
2561
animal organ morphogenesis
1046
heart morphogenesis
260
cardiac epithelial to mesenchymal transition
37
epithelial to mesenchymal transition involved in cardiac fibroblast development
2
Path 2
Term
Annotations
biological_process
12182
developmental process
5761
anatomical structure development
5413
multicellular organism development
4686
system development
4283
circulatory system development
1121
heart development
644
cardiocyte differentiation
179
cardiac cell development
109
cardiac fibroblast cell development
5
epicardium-derived cardiac fibroblast cell development
3
epithelial to mesenchymal transition involved in cardiac fibroblast development
2