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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.



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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr10:107,465,084...107,493,285
Ensembl chr10:110,914,222...110,942,394
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G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15332
    developmental process 6158
      anatomical structure morphogenesis 2694
        animal organ morphogenesis 1082
          heart morphogenesis 268
            cardiac epithelial to mesenchymal transition 37
              epithelial to mesenchymal transition involved in cardiac fibroblast development 2
Path 2
Term Annotations click to browse term
  biological_process 15332
    developmental process 6158
      anatomical structure development 5749
        multicellular organism development 4937
          system development 4508
            circulatory system development 1172
              heart development 663
                cardiocyte differentiation 183
                  cardiac cell development 110
                    cardiac fibroblast cell development 5
                      epicardium-derived cardiac fibroblast cell development 3
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 2
paths to the root