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ONTOLOGY REPORT - ANNOTATIONS


Term:epicardium-derived cardiac fibroblast cell development
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Accession:GO:0060939 term browser browse the term
Definition:The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.



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epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) RGD PMID:17704211 MGI:3818140 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir21 microRNA 21 involved_in ISO (PMID:23441172) RGD PMID:23441172 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Pdcd4 programmed cell death 4 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular developmental process 4533
        cell development 2535
          cardiac cell development 120
            cardiac fibroblast cell development 6
              epicardium-derived cardiac fibroblast cell development 4
                epithelial to mesenchymal transition involved in cardiac fibroblast development 3
Path 2
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      anatomical structure development 6368
        multicellular organism development 5437
          system development 4939
            circulatory system development 1324
              heart development 716
                cardiocyte differentiation 202
                  cardiac fibroblast cell differentiation 6
                    cardiac fibroblast cell development 6
                      epicardium-derived cardiac fibroblast cell development 4
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 3
paths to the root