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ONTOLOGY REPORT - ANNOTATIONS


Term:epicardium-derived cardiac fibroblast cell differentiation
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Accession:GO:0060938 term browser browse the term
Definition:The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


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epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) RGD PMID:17704211 MGI:3818140 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd4 programmed cell death 4 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
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G Spry1 sprouty RTK signaling antagonist 1 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      cellular developmental process 4463
        cell differentiation 4367
          cardiocyte differentiation 185
            cardiac fibroblast cell differentiation 3
              epicardium-derived cardiac fibroblast cell differentiation 3
                epicardium-derived cardiac fibroblast cell development + 3
                epicardium-derived cardiac fibroblast cell fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      anatomical structure development 6182
        multicellular organism development 5619
          system development 5290
            circulatory system development 1231
              heart development 694
                cardiocyte differentiation 185
                  cardiac fibroblast cell differentiation 3
                    epicardium-derived cardiac fibroblast cell differentiation 3
                      epicardium-derived cardiac fibroblast cell development + 3
                      epicardium-derived cardiac fibroblast cell fate commitment 0
paths to the root