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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac fibroblast cell differentiation
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Accession:GO:0060935 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


show annotations for term's descendants           Sort by:
cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:27477354 RGD:151665478 NCBI chr 5:17,314,322...17,350,726
Ensembl chr 5:17,314,276...17,350,722 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27477354 RGD:151665478 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967 		JBrowse link
epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) BHF-UCL PMID:17704211 MGI:3818140 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,110,072...125,316,796 		JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA mir-21 involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr14:121,271,824...121,334,767
Ensembl chr14:121,305,629...121,338,740 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 8:100,449,476...100,863,780
Ensembl chr 8:100,450,266...100,863,446 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17410
    developmental process 6531
      cellular developmental process 4376
        cell differentiation 4375
          cardiocyte differentiation 201
            cardiac fibroblast cell differentiation 6
              cardiac fibroblast cell development + 6
              cardiac fibroblast cell fate commitment + 0
              epicardium-derived cardiac fibroblast cell differentiation + 4
              neural crest-derived cardiac fibroblast cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 17410
    developmental process 6531
      anatomical structure development 6148
        multicellular organism development 4959
          system development 4298
            circulatory system development 1311
              heart development 714
                cardiocyte differentiation 201
                  cardiac fibroblast cell differentiation 6
                    cardiac fibroblast cell development + 6
                    cardiac fibroblast cell fate commitment + 0
                    epicardium-derived cardiac fibroblast cell differentiation + 4
                    neural crest-derived cardiac fibroblast cell differentiation + 0
paths to the root