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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac fibroblast cell differentiation
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Accession:GO:0060935 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.



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cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor, type 1B involved_in ISO RGD
MGI
PMID:27477354 GO_REF:0000096 MGI:4417868 RGD:151665478 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565
JBrowse link
G Inhba inhibin beta-A involved_in ISO RGD
MGI
PMID:27477354 GO_REF:0000096 MGI:4417868 RGD:151665478 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
JBrowse link
epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfbr3 transforming growth factor, beta receptor III involved_in IMP (MGI:3818140|PMID:17704211) BHF-UCL PMID:17704211 MGI:3818140 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495
JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir21a microRNA 21a involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 3:37,694,096...37,698,748
Ensembl chr 3:37,694,096...37,698,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28698
    developmental process 7338
      cellular developmental process 5023
        cell differentiation 5022
          cardiocyte differentiation 221
            cardiac fibroblast cell differentiation 6
              cardiac fibroblast cell development + 6
              cardiac fibroblast cell fate commitment + 0
              epicardium-derived cardiac fibroblast cell differentiation + 4
              neural crest-derived cardiac fibroblast cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 28698
    developmental process 7338
      anatomical structure development 6812
        multicellular organism development 5401
          system development 4625
            circulatory system development 1418
              heart development 753
                cardiocyte differentiation 221
                  cardiac fibroblast cell differentiation 6
                    cardiac fibroblast cell development + 6
                    cardiac fibroblast cell fate commitment + 0
                    epicardium-derived cardiac fibroblast cell differentiation + 4
                    neural crest-derived cardiac fibroblast cell differentiation + 0
paths to the root