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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac fibroblast cell differentiation
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Accession:GO:0060935 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


show annotations for term's descendants           Sort by:
cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:27477354 RGD:151665478 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27477354 RGD:151665478 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) BHF-UCL PMID:17704211 MGI:3818140 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA mir-21 involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr28:22,198,274...22,227,184
Ensembl chr28:22,198,322...22,226,717 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr19:16,969,869...16,976,573
Ensembl chr19:16,970,904...16,972,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16839
    developmental process 6433
      cellular developmental process 4285
        cell differentiation 4284
          cardiocyte differentiation 201
            cardiac fibroblast cell differentiation 6
              cardiac fibroblast cell development + 6
              cardiac fibroblast cell fate commitment + 0
              epicardium-derived cardiac fibroblast cell differentiation + 4
              neural crest-derived cardiac fibroblast cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 16839
    developmental process 6433
      anatomical structure development 6065
        multicellular organism development 4941
          system development 4269
            circulatory system development 1321
              heart development 714
                cardiocyte differentiation 201
                  cardiac fibroblast cell differentiation 6
                    cardiac fibroblast cell development + 6
                    cardiac fibroblast cell fate commitment + 0
                    epicardium-derived cardiac fibroblast cell differentiation + 4
                    neural crest-derived cardiac fibroblast cell differentiation + 0
paths to the root