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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac fibroblast cell differentiation
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Accession:GO:0060935 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


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epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) BHF-UCL PMID:17704211 MGI:3818140 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121
JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr28:22,198,274...22,227,184
Ensembl chr28:22,198,322...22,226,717
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr19:16,969,869...16,976,573
Ensembl chr19:16,970,904...16,972,089
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16216
    developmental process 6377
      cellular developmental process 4224
        cell differentiation 4129
          cardiocyte differentiation 184
            cardiac fibroblast cell differentiation 3
              cardiac fibroblast cell development + 3
              cardiac fibroblast cell fate commitment + 0
              epicardium-derived cardiac fibroblast cell differentiation + 3
              neural crest-derived cardiac fibroblast cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 16216
    developmental process 6377
      anatomical structure development 5910
        multicellular organism development 5376
          system development 5069
            circulatory system development 1208
              heart development 684
                cardiocyte differentiation 184
                  cardiac fibroblast cell differentiation 3
                    cardiac fibroblast cell development + 3
                    cardiac fibroblast cell fate commitment + 0
                    epicardium-derived cardiac fibroblast cell differentiation + 3
                    neural crest-derived cardiac fibroblast cell differentiation + 0
paths to the root