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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac fibroblast cell differentiation
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Accession:GO:0060935 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


show annotations for term's descendants           Sort by:
cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:27477354 RGD:151665478 NCBI chr12:36,765,655...36,811,355
Ensembl chr12:37,541,867...37,566,660 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27477354 RGD:151665478 NCBI chr 7:42,538,591...42,556,578
Ensembl chr 7:42,580,730...42,595,097 		JBrowse link
epicardium-derived cardiac fibroblast cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) BHF-UCL PMID:17704211 MGI:3818140 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587 		JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr10:107,465,084...107,493,285
Ensembl chr10:110,914,222...110,942,394 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15680
    developmental process 6222
      cellular developmental process 4114
        cell differentiation 4113
          cardiocyte differentiation 186
            cardiac fibroblast cell differentiation 5
              cardiac fibroblast cell development + 5
              cardiac fibroblast cell fate commitment + 0
              epicardium-derived cardiac fibroblast cell differentiation + 3
              neural crest-derived cardiac fibroblast cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 15680
    developmental process 6222
      anatomical structure development 5858
        multicellular organism development 4762
          system development 4115
            circulatory system development 1208
              heart development 687
                cardiocyte differentiation 186
                  cardiac fibroblast cell differentiation 5
                    cardiac fibroblast cell development + 5
                    cardiac fibroblast cell fate commitment + 0
                    epicardium-derived cardiac fibroblast cell differentiation + 3
                    neural crest-derived cardiac fibroblast cell differentiation + 0
paths to the root